Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hexb

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HEXB
- Mouse genes Hexb
- Rat genes Hexb
- Zfish genes hexb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hexb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008375	acetylglucosaminyltransferase activity	HEXB	IDA		Human	PMID:25645918
Molecular Function	GO:0016231	beta-N-acetylglucosaminidase activity	Hexb	IDA		Rat	PMID:1397486\|RGD:1599434
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	HEXB	IDA		Human	PMID:8123671
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	HEXB	IDA		Human	PMID:8672428
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	MGI:MGI:6508661\|PMID:8253842
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:22451654
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:11707436
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:28728022
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:7203014
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:8269854
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:8789434
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:26681805
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:35482418
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:11854359
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:9122231
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexb	IDA		Mouse	PMID:9417048
Molecular Function	GO:0030246	carbohydrate binding	Hexb	IDA		Rat	PMID:8702598\|RGD:1625498
Molecular Function	GO:0015929	hexosaminidase activity	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:22451654
Molecular Function	GO:0015929	hexosaminidase activity	Hexb	IDA		Rat	PMID:8702598\|RGD:1625498
Molecular Function	GO:0015929	hexosaminidase activity	hexb	IMP	ZFIN:ZDB-CRISPR-200130-3	Zfish	PMID:31140649
Molecular Function	GO:0015929	hexosaminidase activity	hexb	IMP	ZFIN:ZDB-GENO-200609-7	Zfish	PMID:31140649
Molecular Function	GO:0016787	hydrolase activity	Hexb	IDA		Mouse	PMID:19710420
Molecular Function	GO:0042802	identical protein binding	HEXB	IDA		Human	PMID:6230359
Molecular Function	GO:0042802	identical protein binding	Hexb	IPI	PR:P20060	Mouse	PMID:8269854
Molecular Function	GO:0042802	identical protein binding	Hexb	IPI	RGD:1307607	Rat	PMID:1397486\|RGD:1599434
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:P06865	Human	PMID:16698036
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:P06865	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:O00308	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:O75808	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:O75925	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:O95164	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:P98170	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q04724	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q05516	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q13064	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q13564	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q6NW29	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q7KZS0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q8IWV7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q8IYU4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q8N4N3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q8NFH3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q8TBB1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q96D59	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q96FW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q96PM5-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q9GZY0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q9H347	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q9UHD9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q9UNS2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HEXB	IPI	UniProtKB:Q9Y575-3	Human	PMID:32814053
Molecular Function	GO:0044877	protein-containing complex binding	Hexb	IDA		Rat	PMID:1397486\|RGD:1599434
Cellular Component	GO:0001669	acrosomal vesicle	Hexb	IDA		Mouse	PMID:8269854
Cellular Component	GO:0042582	azurophil granule	HEXB	IDA		Human	PMID:25645918
Cellular Component	GO:1905379	beta-N-acetylhexosaminidase complex	HEXB	IPI		Human	PMID:16698036
Cellular Component	GO:0060473	cortical granule	Hexb	IDA		Mouse	MGI:MGI:6508661\|PMID:8253842
Cellular Component	GO:0070062	extracellular exosome	HEXB	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Hexb	IDA		Mouse	PMID:19710420
Cellular Component	GO:0005615	extracellular space	Hexb	IDA		Mouse	PMID:35482418
Cellular Component	GO:0005764	lysosome	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:22451654
Cellular Component	GO:0005764	lysosome	Hexb	IDA		Mouse	PMID:9774663
Cellular Component	GO:0005764	lysosome	Hexb	IDA		Mouse	PMID:8286571
Cellular Component	GO:0005764	lysosome	Hexb	IDA		Mouse	PMID:29514215
Cellular Component	GO:0005764	lysosome	Hexb	IDA		Mouse	PMID:11854359
Cellular Component	GO:0005764	lysosome	Hexb	IDA		Rat	PMID:8702598\|RGD:1625498
Cellular Component	GO:0005764	lysosome	Hexb	IDA		Rat	PMID:9041125\|RGD:1599437
Cellular Component	GO:0016020	membrane	HEXB	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Hexb	IDA		Mouse	PMID:11854359
Biological Process	GO:0001525	angiogenesis	hexb	IMP	ZFIN:ZDB-MRPHLNO-090617-7	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	hexb	IMP	ZFIN:ZDB-MRPHLNO-090617-8	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	hexb	IMP	ZFIN:ZDB-MRPHLNO-090617-7,ZFIN:ZDB-MRPHLNO-090617-8	Zfish	PMID:19389629
Biological Process	GO:0043615	astrocyte cell migration	Hexb	IMP		Mouse	MGI:MGI:3044466\|PMID:15155903
Biological Process	GO:0030207	chondroitin sulfate catabolic process	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:22451654
Biological Process	GO:0030209	dermatan sulfate catabolic process	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:11707436
Biological Process	GO:0006689	ganglioside catabolic process	HEXB	IDA		Human	PMID:8123671
Biological Process	GO:0006689	ganglioside catabolic process	HEXB	IDA		Human	PMID:8672428
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:12657883
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:15748167
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:10021458
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:12756243
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:8789434
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:9223328
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP		Mouse	PMID:8566348
Biological Process	GO:0006689	ganglioside catabolic process	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:9645704
Biological Process	GO:0030203	glycosaminoglycan metabolic process	HEXB	IDA		Human	PMID:11707436
Biological Process	GO:0030203	glycosaminoglycan metabolic process	HEXB	IDA		Human	PMID:25645918
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Hexb	IMP		Mouse	MGI:MGI:3722584\|PMID:11707436
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Biological Process	GO:0006687	glycosphingolipid metabolic process	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:8789434
Biological Process	GO:0030214	hyaluronan catabolic process	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:22451654
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Hexb	IGI	MGI:MGI:88110	Mouse	PMID:12756243
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:12756243
Biological Process	GO:0019915	lipid storage	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:8789434
Biological Process	GO:0019915	lipid storage	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:7550345
Biological Process	GO:0019915	lipid storage	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:9223328
Biological Process	GO:0019915	lipid storage	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:10021458
Biological Process	GO:0019915	lipid storage	Hexb	IGI	MGI:MGI:1342057	Mouse	PMID:10021458
Biological Process	GO:0007626	locomotory behavior	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:7550345
Biological Process	GO:0007626	locomotory behavior	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Biological Process	GO:0007040	lysosome organization	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:9184660
Biological Process	GO:0007040	lysosome organization	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Biological Process	GO:0007040	lysosome organization	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:9645704
Biological Process	GO:0007040	lysosome organization	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:8789434
Biological Process	GO:0051651	maintenance of location in cell	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:8789434
Biological Process	GO:0051651	maintenance of location in cell	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:7550345
Biological Process	GO:0051651	maintenance of location in cell	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:9223328
Biological Process	GO:0008049	male courtship behavior	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:12617783
Biological Process	GO:0042552	myelination	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:9184660
Biological Process	GO:0006044	N-acetylglucosamine metabolic process	Hexb	IDA		Rat	PMID:1397486\|RGD:1599434
Biological Process	GO:0050905	neuromuscular process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:10021458
Biological Process	GO:0050905	neuromuscular process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:9584189
Biological Process	GO:0050905	neuromuscular process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:7550345
Biological Process	GO:0050885	neuromuscular process controlling balance	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:7550345
Biological Process	GO:0050885	neuromuscular process controlling balance	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:10021458
Biological Process	GO:0050885	neuromuscular process controlling balance	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:9584189
Biological Process	GO:0050885	neuromuscular process controlling balance	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Biological Process	GO:0070050	neuron cellular homeostasis	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:12756243
Biological Process	GO:0070050	neuron cellular homeostasis	Hexb	IGI	MGI:MGI:88110	Mouse	PMID:12756243
Biological Process	GO:0009313	oligosaccharide catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:10021458
Biological Process	GO:0009313	oligosaccharide catabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:15748167
Biological Process	GO:0048477	oogenesis	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:9223328
Biological Process	GO:0007341	penetration of zona pellucida	Hexb	IMP		Mouse	PMID:8269854
Biological Process	GO:0008654	phospholipid biosynthetic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:15198669
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hexb	IMP		Mouse	MGI:MGI:3044466\|PMID:15155903
Biological Process	GO:0019538	protein metabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:12657883
Biological Process	GO:0008360	regulation of cell shape	Hexb	IMP		Mouse	MGI:MGI:3044466\|PMID:15155903
Biological Process	GO:0031323	regulation of cellular metabolic process	Hexb	IMP	MGI:MGI:1857438	Mouse	PMID:15198669
Biological Process	GO:0007605	sensory perception of sound	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Biological Process	GO:0019953	sexual reproduction	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:9645704
Biological Process	GO:0007338	single fertilization	Hexb	IDA		Mouse	MGI:MGI:6508661\|PMID:8253842
Biological Process	GO:0007338	single fertilization	Hexb	IMP	MGI:MGI:2429701	Mouse	PMID:12756243
Biological Process	GO:0001501	skeletal system development	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:8896570
Biological Process	GO:0001501	skeletal system development	Hexb	IGI	MGI:MGI:96073	Mouse	PMID:9184660

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.