Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HEXIM2
  • Mouse genes Hexim2
  • Rat genes Hexim2
  • Zfish genes hexim1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hexim2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097322	7SK snRNA binding	HEXIM2	IDA		Human	PMID:19883659
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	HEXIM2	IDA		Human	PMID:15713662
Molecular Function	GO:0042802	identical protein binding	HEXIM2	IPI	UniProtKB:Q96MH2	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	HEXIM2	IPI	UniProtKB:Q96MH2	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	HEXIM2	IPI	UniProtKB:Q96MH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O94992	Human	PMID:15713661
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P50750	Human	PMID:15713662
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O60563	Human	PMID:19883659
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O60583-2	Human	PMID:19883659
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P52292	Human	PMID:19883659
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q99081	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q9GZV8	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:D3DU92	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O43597	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O43609	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O75528	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P11309	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P15976	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q13526	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q8IYA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q99081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q9GZV8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O43865	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O94992	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q99081-3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O00505	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O43310-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O43865	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O60304	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O94992	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P27918	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q08289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q13526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q13829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q14142	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q15287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q32M78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q3B820	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q3SY46	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q5FWF6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q7Z699	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q8IYX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q8NFT6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q96CW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q96NG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q9BUY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HEXIM2	IPI	UniProtKB:Q9UHF1	Human	PMID:32296183
Molecular Function	GO:0017069	snRNA binding	HEXIM2	IDA		Human	PMID:15713662
Cellular Component	GO:0005829	cytosol	HEXIM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	HEXIM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HEXIM2	IDA		Human	GO_REF:0000052
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	HEXIM2	IDA		Human	PMID:15713662
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HEXIM2	IDA		Human	PMID:15713662
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HEXIM2	IDA		Human	PMID:15713662
Biological Process	GO:0065003	protein-containing complex assembly	hexim1	IPI	ZFIN:ZDB-GENE-030131-321,ZFIN:ZDB-GENE-030131-4637,ZFIN:ZDB-GENE-030131-6397	Zfish	PMID:31183407

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern