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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hhip

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hhip
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0097108hedgehog family protein bindingHHIPIPIUniProtKB:O43323HumanPMID:19561611
Molecular FunctionGO:0097108hedgehog family protein bindingHHIPIPIUniProtKB:Q62226HumanPMID:19561611
Molecular FunctionGO:0005515protein bindingHHIPIPIUniProtKB:Q15465HumanPMID:19561609
Molecular FunctionGO:0005515protein bindingHhipIPIPR:P97812MousePMID:10050855
Molecular FunctionGO:0005515protein bindingHhipIPIPR:Q62226MousePMID:10050855
Molecular FunctionGO:0005515protein bindingHhipIPIPR:Q61488MousePMID:10050855
Molecular FunctionGO:0008270zinc ion bindingHHIPIDAHumanPMID:19561609
Cellular ComponentGO:0009986cell surfaceHhipIDAMousePMID:15576403
Cellular ComponentGO:0005737cytoplasmHhipIDARatPMID:19515211|RGD:11552601
Cellular ComponentGO:0005634nucleusHhipIDARatPMID:19515211|RGD:11552601
Cellular ComponentGO:0005886plasma membraneHhipIDAMousePMID:10050855
Cellular ComponentGO:0005886plasma membraneHhipIDARatPMID:19515211|RGD:11552601
Cellular ComponentGO:0005886plasma membranehhipIDAZfishPMID:16765934
Biological ProcessGO:0009887animal organ morphogenesisHhipIMPMGI:MGI:2450891MousePMID:12917290
Biological ProcessGO:0009953dorsal/ventral pattern formationHhipIGIMGI:MGI:105373MousePMID:15576403
Biological ProcessGO:0060441epithelial tube branching involved in lung morphogenesisHhipIMPMGI:MGI:2450891MousePMID:12569124
Biological ProcessGO:0033333fin developmenthhipIMPZfishPMID:9007245
Biological ProcessGO:0043066negative regulation of apoptotic processHhipIMPRatPMID:19515211|RGD:11552601
Biological ProcessGO:0048635negative regulation of muscle organ developmenthhipIGIZFIN:ZDB-MRPHLNO-050308-1,ZFIN:ZDB-MRPHLNO-050308-3ZfishPMID:16765934
Biological ProcessGO:0048635negative regulation of muscle organ developmenthhipIGIZFIN:ZDB-GENE-980526-44ZfishPMID:16765934
Biological ProcessGO:0048635negative regulation of muscle organ developmenthhipIDAZfishPMID:16765934
Biological ProcessGO:0048635negative regulation of muscle organ developmenthhipIMPZFIN:ZDB-MRPHLNO-061130-1,ZFIN:ZDB-MRPHLNO-061130-2ZfishPMID:16765934
Biological ProcessGO:0009968negative regulation of signal transductionHHIPIDAHumanPMID:19561609
Biological ProcessGO:0009968negative regulation of signal transductionhhipIDAZfishPMID:16765934
Biological ProcessGO:0009968negative regulation of signal transductionhhipIMPZFIN:ZDB-MRPHLNO-061130-1,ZFIN:ZDB-MRPHLNO-061130-2ZfishPMID:16765934
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayHhipIDAMouseMGI:MGI:5284801|PMID:15294024
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayHhipIMPMGI:MGI:2450891MousePMID:12569124
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayHhipIDAMousePMID:10050855
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayhhipIMPZFIN:ZDB-GENO-060825-17ZfishPMID:16121254
Biological ProcessGO:0007405neuroblast proliferationHhipIGIMGI:MGI:105373MousePMID:15576403
Biological ProcessGO:0040036regulation of fibroblast growth factor receptor signaling pathwayHhipIMPMGI:MGI:2450891MousePMID:12569124
Biological ProcessGO:0007165signal transductionHhipIDAMousePMID:10050855
Biological ProcessGO:0048705skeletal system morphogenesisHhipIMPMouseMGI:MGI:1333378|PMID:10050855

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory