Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIF1A
  • Mouse genes Hif1a
  • Rat genes Hif1a
  • Zfish genes hif1aa,hif1ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hif1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	hif1ab	IDA		Zfish	PMID:23421720
Molecular Function	GO:0003677	DNA binding	Hif1a	IDA		Mouse	PMID:15456877
Molecular Function	GO:0001216	DNA-binding transcription activator activity	HIF1A	IMP		Human	PMID:33108349
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HIF1A	IDA		Human	PMID:19782034
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HIF1A	IMP		Human	PMID:24983504
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hif1a	IMP		Mouse	MGI:MGI:6430928|PMID:25587068
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hif1a	IDA		Mouse	PMID:21856340
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HIF1A	IDA		Human	PMID:11782478
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HIF1A	IDA		Human	PMID:15261140
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HIF1A	IDA		Human	PMID:18658046
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HIF1A	IDA		Human	PMID:25043030
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HIF1A	IDA		Human	PMID:30125331
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hif1a	IDA		Mouse	PMID:15456877
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	HIF1A	IDA		Human	PMID:7539918
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	HIF1A	IDA		Human	PMID:8756616
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	HIF1A	IDA		Human	PMID:8387214
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	HIF1A	IDA		Human	PMID:9079689
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Hif1a	IDA		Mouse	PMID:24030251
Molecular Function	GO:0070888	E-box binding	Hif1a	IMP		Mouse	MGI:MGI:5528778|PMID:24011070
Molecular Function	GO:0019899	enzyme binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:11641274
Molecular Function	GO:0042826	histone deacetylase binding	Hif1a	IPI	UniProtKB:P56524|UniProtKB:Q9UQL6	Mouse	MGI:MGI:3821919|PMID:19071119
Molecular Function	GO:0051879	Hsp90 protein binding	HIF1A	IDA		Human	PMID:9079689
Molecular Function	GO:0016922	nuclear receptor binding	HIF1A	IPI	UniProtKB:P35398	Human	PMID:18658046
Molecular Function	GO:0002039	p53 binding	HIF1A	EXP		Human	PMID:15629713
Molecular Function	GO:0002039	p53 binding	HIF1A	IDA		Human	PMID:15629713
Molecular Function	GO:0002039	p53 binding	HIF1A	IPI	UniProtKB:P04637	Human	PMID:15629713
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:11292862
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P45481	Human	PMID:11959977
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:12004076
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:12050673
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:12446723
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:14668441
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:15261140
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:15721254
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q13438	Human	PMID:15721254
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9H6Z9	Human	PMID:15721254
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9UHD8-1	Human	PMID:16424018
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q13330	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q96KS0	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9GZT9	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9H6Z9	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q92831	Human	PMID:16543236
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P08047	Human	PMID:17024177
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q96KS0	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9GZT9	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9H6Z9	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:17382325
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q92793	Human	PMID:17382325
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P10275	Human	PMID:17426252
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:18268343
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:18323857
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P46531	Human	PMID:18427106
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P11474	Human	PMID:18509053
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q61539	Human	PMID:18509053
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:O94888	Human	PMID:18775313
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:19071119
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:19071119
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:19680224
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:20603618
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:20603618
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P63165	Human	PMID:20661221
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q8N2W9	Human	PMID:20661221
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9GZT9	Human	PMID:20840591
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:20932347
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:21602890
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q92793	Human	PMID:21602890
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P14618-1	Human	PMID:21620138
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:21620138
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P49407	Human	PMID:21685944
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P51450-2	Human	PMID:21871655
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q8BIF2	Human	PMID:21871655
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:O94966	Human	PMID:22128162
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P25789	Human	PMID:22801492
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q99PV5	Human	PMID:22801492
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9C0J9	Human	PMID:22801492
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q5RIX9	Human	PMID:22903062
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q6S7F2	Human	PMID:22903062
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337,UniProtKB:P62877,UniProtKB:Q13617	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337,UniProtKB:P62877,UniProtKB:Q13617,UniProtKB:Q15370	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337,UniProtKB:P62877,UniProtKB:Q13617,UniProtKB:Q16665	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337,UniProtKB:Q13617,UniProtKB:Q96GG9	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q96GG9	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9Y3V2	Human	PMID:23469069
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:23746844
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40818	Human	PMID:24378640
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:24421387
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q96CJ1	Human	PMID:24421387
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:O00257	Human	PMID:24434214
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:24434214
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P63165	Human	PMID:24434214
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P35222	Human	PMID:24650032
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P17861	Human	PMID:24670641
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q8IXJ6	Human	PMID:24681946
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9GZT9	Human	PMID:24681946
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:24899725
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P09467	Human	PMID:25043030
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:25438054
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:O75081	Human	PMID:25974097
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9GZT9	Human	PMID:25974097
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P07900	Human	PMID:26517842
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P08238	Human	PMID:26517842
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:26751287
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:26751287
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:26752685
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9H6Z9	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9NWT6	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P23771	Human	PMID:28263977
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P84022	Human	PMID:28471448
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q9H6Z9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:9704006
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:9887100
Molecular Function	GO:0005515	protein binding	HIF1A	IPI	UniProtKB:Q92793	Human	PMID:9887100
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	UniProtKB:P51450-2|UniProtKB:Q8BIF2	Mouse	MGI:MGI:5289736|PMID:21871655
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	UniProtKB:P35583|UniProtKB:Q09472	Mouse	MGI:MGI:4461337|PMID:20609350
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	UniProtKB:Q6NY15	Mouse	MGI:MGI:3640039|PMID:16777103
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	UniProtKB:Q0VBL6-2	Mouse	MGI:MGI:5526927|PMID:21546903
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	UniProtKB:Q0VBL6	Mouse	MGI:MGI:5526927|PMID:21546903
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	UniProtKB:P40337	Mouse	MGI:MGI:5572900|PMID:11292862
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	PR:P53762	Mouse	PMID:20440072
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	PR:P53762	Mouse	PMID:26245371
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	PR:P53762	Mouse	PMID:8702901
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	PR:Q8K4M5	Mouse	PMID:17371845
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	RGD:1310644	Rat	PMID:19950214|RGD:2317359
Molecular Function	GO:0005515	protein binding	Hif1a	IPI	RGD:3960	Rat	PMID:19950214|RGD:2317359
Molecular Function	GO:0019904	protein domain specific binding	HIF1A	IPI	UniProtKB:P45481	Human	PMID:14594809
Molecular Function	GO:0046982	protein heterodimerization activity	HIF1A	IPI	UniProtKB:Q9HBZ2	Human	PMID:12239177
Molecular Function	GO:0046982	protein heterodimerization activity	HIF1A	IPI	UniProtKB:P27540	Human	PMID:9079689
Molecular Function	GO:0046982	protein heterodimerization activity	Hif1a	IDA		Mouse	MGI:MGI:5927132|PMID:26245371
Molecular Function	GO:0019901	protein kinase binding	HIF1A	IPI	UniProtKB:Q9H4B4	Human	PMID:20889502
Molecular Function	GO:0044877	protein-containing complex binding	Hif1a	IMP		Rat	PMID:10559391|RGD:2313660
Molecular Function	GO:0044877	protein-containing complex binding	Hif1a	IDA		Rat	PMID:11029639|RGD:2301215
Molecular Function	GO:0044877	protein-containing complex binding	Hif1a	IPI	RGD:2126|RGD:620036	Rat	PMID:15084519|RGD:2312278
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HIF1A	IMP		Human	PMID:33108349
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hif1a	IDA		Mouse	MGI:MGI:6430928|PMID:25587068
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hif1a	IGI	MGI:MGI:88071	Mouse	PMID:9113979
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HIF1A	IDA		Human	PMID:19782034
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	HIF1A	IPI	UniProtKB:P27540	Human	PMID:7539918
Molecular Function	GO:0043565	sequence-specific DNA binding	HIF1A	IDA		Human	PMID:7539918
Molecular Function	GO:0043565	sequence-specific DNA binding	HIF1A	IDA		Human	PMID:8756616
Molecular Function	GO:0043565	sequence-specific DNA binding	HIF1A	IDA		Human	PMID:9079689
Molecular Function	GO:0043565	sequence-specific DNA binding	Hif1a	IDA		Mouse	MGI:MGI:5927132|PMID:26245371
Molecular Function	GO:0043565	sequence-specific DNA binding	Hif1a	IDA		Mouse	PMID:9368100
Molecular Function	GO:0043565	sequence-specific DNA binding	Hif1a	IDA		Mouse	PMID:24030251
Molecular Function	GO:0043565	sequence-specific DNA binding	Hif1a	IDA		Rat	PMID:18614764|RGD:2301848
Molecular Function	GO:0000976	transcription cis-regulatory region binding	hif1ab	IDA		Zfish	PMID:27222589
Molecular Function	GO:0001223	transcription coactivator binding	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:15261140
Molecular Function	GO:0140537	transcription regulator activator activity	HIF1A	IPI	UniProtKB:Q09472	Human	PMID:11063749
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HIF1A	IPI	UniProtKB:P40337	Human	PMID:11641274
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Hif1a	IPI	RGD:1305332	Rat	PMID:19950214|RGD:2317359
Cellular Component	GO:0000785	chromatin	HIF1A	IDA		Human	PMID:19782034
Cellular Component	GO:0005737	cytoplasm	HIF1A	IDA		Human	PMID:19651758
Cellular Component	GO:0005737	cytoplasm	HIF1A	IDA		Human	PMID:24048733
Cellular Component	GO:0005737	cytoplasm	Hif1a	IDA		Rat	PMID:11237857|RGD:68201
Cellular Component	GO:0005829	cytosol	HIF1A	IDA		Human	PMID:24681946
Cellular Component	GO:0000791	euchromatin	Hif1a	IDA		Mouse	MGI:MGI:6430928|PMID:25587068
Cellular Component	GO:0031514	motile cilium	Hif1a	IDA		Mouse	PMID:11818497
Cellular Component	GO:0016604	nuclear body	HIF1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	Hif1a	IDA		Mouse	MGI:MGI:5526927|PMID:21546903
Cellular Component	GO:0005654	nucleoplasm	HIF1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:15261140
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:18658046
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:20810912
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:20972335
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:24048733
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:25043030
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:8089148
Cellular Component	GO:0005634	nucleus	HIF1A	IDA		Human	PMID:22848707
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	MGI:MGI:5526927|PMID:21546903
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	MGI:MGI:5558956|PMID:24553947
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	MGI:MGI:5315694|PMID:18295594
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	PMID:20440072
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	PMID:22009797
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	PMID:15016652
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	PMID:15456877
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	PMID:24030251
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Mouse	PMID:11691837
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Rat	PMID:11313887|RGD:1581932
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Rat	PMID:12675925|RGD:632652
Cellular Component	GO:0005634	nucleus	Hif1a	IDA		Rat	PMID:18614764|RGD:2301848
Cellular Component	GO:0032991	protein-containing complex	HIF1A	IMP		Human	PMID:14594809
Cellular Component	GO:0032991	protein-containing complex	HIF1A	IMP		Human	PMID:15629713
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	HIF1A	IDA		Human	PMID:7539918
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	HIF1A	IDA		Human	PMID:8756616
Biological Process	GO:0006953	acute-phase response	Hif1a	IEP		Rat	PMID:19840250|RGD:10395370
Biological Process	GO:0001525	angiogenesis	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15073147
Biological Process	GO:0001525	angiogenesis	Hif1a	IMP	MGI:MGI:2179429	Mouse	PMID:14659802
Biological Process	GO:0006915	apoptotic process	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:17181398
Biological Process	GO:0019896	axonal transport of mitochondrion	HIF1A	IMP		Human	PMID:19528298
Biological Process	GO:0001922	B-1 B cell homeostasis	Hif1a	IMP		Mouse	PMID:11854513
Biological Process	GO:0001568	blood vessel development	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:9436976
Biological Process	GO:0048514	blood vessel morphogenesis	Hif1a	IMP	MGI:MGI:2385358	Mouse	PMID:9606183
Biological Process	GO:0030282	bone mineralization	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:17181398
Biological Process	GO:0048593	camera-type eye morphogenesis	Hif1a	IGI	MGI:MGI:103223	Mouse	PMID:22627278
Biological Process	GO:0003208	cardiac ventricle morphogenesis	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:9436976
Biological Process	GO:0051216	cartilage development	Hif1a	IMP	MGI:MGI:2386649,MGI:MGI:2386679	Mouse	PMID:11691837
Biological Process	GO:0030154	cell differentiation	Hif1a	IGI	MGI:MGI:109169	Mouse	PMID:16287860
Biological Process	GO:0071245	cellular response to carbon monoxide	Hif1a	IEP		Rat	PMID:17475674|RGD:9068879
Biological Process	GO:0071279	cellular response to cobalt ion	Hif1a	IEP		Rat	PMID:10559391|RGD:2313660
Biological Process	GO:1903928	cellular response to cyanide	Hif1a	IEP		Rat	PMID:21854848|RGD:9068914
Biological Process	GO:0071257	cellular response to electrical stimulus	Hif1a	IEP		Rat	PMID:12193088|RGD:9068876
Biological Process	GO:0071391	cellular response to estrogen stimulus	Hif1a	IEP		Rat	PMID:17272396|RGD:152177689
Biological Process	GO:0071333	cellular response to glucose stimulus	Hif1a	IEP		Rat	PMID:12234775|RGD:9068918
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Hif1a	IEP		Rat	PMID:16735674|RGD:8693740
Biological Process	GO:0071456	cellular response to hypoxia	HIF1A	IDA		Human	PMID:11573933
Biological Process	GO:0071456	cellular response to hypoxia	HIF1A	IDA		Human	PMID:19528298
Biological Process	GO:0071456	cellular response to hypoxia	HIF1A	IEP		Human	PMID:19782034
Biological Process	GO:0071456	cellular response to hypoxia	HIF1A	IEP		Human	PMID:20810912
Biological Process	GO:0071456	cellular response to hypoxia	HIF1A	IDA		Human	PMID:20889502
Biological Process	GO:0071456	cellular response to hypoxia	Hif1a	IGI	MGI:MGI:101884	Mouse	PMID:24011070
Biological Process	GO:0071456	cellular response to hypoxia	Hif1a	IGI	MGI:MGI:3618742	Mouse	PMID:24011070
Biological Process	GO:0071456	cellular response to hypoxia	Hif1a	IGI	MGI:MGI:2676890	Mouse	PMID:24011070
Biological Process	GO:0071456	cellular response to hypoxia	Hif1a	IMP		Rat	PMID:18248612|RGD:9068884
Biological Process	GO:0071456	cellular response to hypoxia	Hif1a	IEP		Rat	PMID:19220706|RGD:9068456
Biological Process	GO:0032869	cellular response to insulin stimulus	Hif1a	IEP		Rat	PMID:16506055|RGD:1626318
Biological Process	GO:0071347	cellular response to interleukin-1	HIF1A	IEP		Human	PMID:12958148
Biological Process	GO:0071347	cellular response to interleukin-1	Hif1a	IEP		Rat	PMID:12101082|RGD:9068871
Biological Process	GO:0071482	cellular response to light stimulus	Hif1a	IEP		Rat	PMID:17475674|RGD:9068879
Biological Process	GO:0071396	cellular response to lipid	Hif1a	IEP		Rat	PMID:19423865|RGD:9068890
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Hif1a	IEP		Rat	PMID:19940979|RGD:5147884
Biological Process	GO:0071260	cellular response to mechanical stimulus	Hif1a	IEP		Rat	PMID:15183444|RGD:9068913
Biological Process	GO:0071250	cellular response to nitrite	Hif1a	IEP		Rat	PMID:23227543|RGD:9068878
Biological Process	GO:0071407	cellular response to organic cyclic compound	Hif1a	IEP		Rat	PMID:9398602|RGD:625724
Biological Process	GO:0097237	cellular response to toxic substance	Hif1a	IEP		Rat	PMID:21854848|RGD:9068914
Biological Process	GO:0098586	cellular response to virus	HIF1A	IDA		Human	PMID:32697943
Biological Process	GO:1904568	cellular response to wortmannin	Hif1a	IEP		Rat	PMID:17272396|RGD:152177689
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Hif1a	IEP		Rat	PMID:20193759|RGD:9068889
Biological Process	GO:0021987	cerebral cortex development	Hif1a	IMP	MGI:MGI:2677899	Mouse	PMID:12972594
Biological Process	GO:0002062	chondrocyte differentiation	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15073147
Biological Process	GO:0032963	collagen metabolic process	Hif1a	IMP		Mouse	MGI:MGI:3772289|PMID:18037992
Biological Process	GO:0002248	connective tissue replacement involved in inflammatory response wound healing	Hif1a	IMP		Mouse	MGI:MGI:3772289|PMID:18037992
Biological Process	GO:0048546	digestive tract morphogenesis	Hif1a	IMP	MGI:MGI:2384429	Mouse	PMID:20808783
Biological Process	GO:0071542	dopaminergic neuron differentiation	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:17215402
Biological Process	GO:0071542	dopaminergic neuron differentiation	Hif1a	IGI	MGI:MGI:103178	Mouse	PMID:17215402
Biological Process	GO:0051541	elastin metabolic process	Hif1a	IMP		Mouse	MGI:MGI:3772289|PMID:18037992
Biological Process	GO:0035162	embryonic hemopoiesis	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:16787915
Biological Process	GO:0001892	embryonic placenta development	Hif1a	IGI	MGI:MGI:109169	Mouse	PMID:16287860
Biological Process	GO:0001892	embryonic placenta development	Hif1a	IMP	MGI:MGI:2179429	Mouse	PMID:16287860
Biological Process	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:12620994
Biological Process	GO:0001837	epithelial to mesenchymal transition	Hif1a	IMP		Mouse	MGI:MGI:3772289|PMID:18037992
Biological Process	GO:0002067	glandular epithelial cell differentiation	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:12620994
Biological Process	GO:0002071	glandular epithelial cell maturation	Hif1a	IMP	MGI:MGI:2384429	Mouse	PMID:20808783
Biological Process	GO:0042593	glucose homeostasis	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15328538
Biological Process	GO:0042593	glucose homeostasis	Hif1a	IMP		Mouse	PMID:17437992
Biological Process	GO:0001947	heart looping	Hif1a	IMP	MGI:MGI:2179429	Mouse	PMID:14659802
Biological Process	GO:0060218	hematopoietic stem cell differentiation	hif1ab	IGI	ZFIN:ZDB-GENE-080917-55	Zfish	PMID:29339404
Biological Process	GO:0060218	hematopoietic stem cell differentiation	hif1ab	IMP	ZFIN:ZDB-GENO-171116-6	Zfish	PMID:29339404
Biological Process	GO:0060218	hematopoietic stem cell differentiation	hif1aa	IMP	ZFIN:ZDB-GENO-171116-6	Zfish	PMID:29339404
Biological Process	GO:0060218	hematopoietic stem cell differentiation	hif1aa	IGI	ZFIN:ZDB-GENE-040426-706	Zfish	PMID:29339404
Biological Process	GO:0060218	hematopoietic stem cell differentiation	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-081120-4	Zfish	PMID:27751871
Biological Process	GO:0060218	hematopoietic stem cell differentiation	hif1ab	IGI	ZFIN:ZDB-GENE-030805-2	Zfish	PMID:27751871
Biological Process	GO:0042541	hemoglobin biosynthetic process	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:16787915
Biological Process	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway	Hif1a	IDA		Mouse	PMID:8470821
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	Hif1a	IMP	MGI:MGI:2677892	Mouse	PMID:20440072
Biological Process	GO:0060574	intestinal epithelial cell maturation	Hif1a	IMP	MGI:MGI:2384429	Mouse	PMID:20808783
Biological Process	GO:0001678	intracellular glucose homeostasis	HIF1A	IDA		Human	PMID:30125331
Biological Process	GO:0006879	intracellular iron ion homeostasis	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:16787915
Biological Process	GO:0032364	intracellular oxygen homeostasis	HIF1A	IDA		Human	PMID:16956324
Biological Process	GO:0032364	intracellular oxygen homeostasis	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:9436976
Biological Process	GO:0061072	iris morphogenesis	Hif1a	IGI	MGI:MGI:103223	Mouse	PMID:22627278
Biological Process	GO:0006089	lactate metabolic process	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15328538
Biological Process	GO:0007595	lactation	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:12620994
Biological Process	GO:1905517	macrophage migration	hif1ab	IGI	ZFIN:ZDB-GENE-080917-55	Zfish	PMID:28524872
Biological Process	GO:1905517	macrophage migration	hif1aa	IGI	ZFIN:ZDB-GENE-040426-706	Zfish	PMID:28524872
Biological Process	GO:0060135	maternal process involved in female pregnancy	Hif1a	IEP		Rat	PMID:20181619|RGD:5147883
Biological Process	GO:0097152	mesenchymal cell apoptotic process	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:10328919
Biological Process	GO:0008045	motor neuron axon guidance	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-130813-1	Zfish	PMID:26681691
Biological Process	GO:0008045	motor neuron axon guidance	hif1ab	IGI	ZFIN:ZDB-GENE-030519-2	Zfish	PMID:26681691
Biological Process	GO:0046716	muscle cell cellular homeostasis	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15328538
Biological Process	GO:0043066	negative regulation of apoptotic process	Hif1a	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0043066	negative regulation of apoptotic process	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:17181398
Biological Process	GO:0043066	negative regulation of apoptotic process	Hif1a	IMP		Rat	PMID:20498255|RGD:5147879
Biological Process	GO:0030502	negative regulation of bone mineralization	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:17181398
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-130813-1	Zfish	PMID:26681691
Biological Process	GO:0010629	negative regulation of gene expression	HIF1A	IMP		Human	PMID:26879375
Biological Process	GO:0045926	negative regulation of growth	Hif1a	IMP	MGI:MGI:2386649,MGI:MGI:2386679	Mouse	PMID:11691837
Biological Process	GO:2001054	negative regulation of mesenchymal cell apoptotic process	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:10328919
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Hif1a	IMP	MGI:MGI:2677899	Mouse	PMID:12972594
Biological Process	GO:0030279	negative regulation of ossification	Hif1a	IMP		Mouse	MGI:MGI:5300390|PMID:22081627
Biological Process	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	HIF1A	IDA		Human	PMID:24899725
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	Hif1a	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0070244	negative regulation of thymocyte apoptotic process	Hif1a	IMP	MGI:MGI:2386679,MGI:MGI:2448686	Mouse	PMID:15456877
Biological Process	GO:0032007	negative regulation of TOR signaling	Hif1a	IMP	MGI:MGI:2384429	Mouse	PMID:20808783
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hif1a	IMP		Rat	PMID:20496369|RGD:5147880
Biological Process	GO:0045906	negative regulation of vasoconstriction	Hif1a	IMP		Rat	PMID:21106323|RGD:5147878
Biological Process	GO:0001755	neural crest cell migration	Hif1a	IMP	MGI:MGI:2179429	Mouse	PMID:14659802
Biological Process	GO:0001755	neural crest cell migration	hif1ab	IGI	ZFIN:ZDB-GENE-030918-2	Zfish	PMID:30031069
Biological Process	GO:0001755	neural crest cell migration	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-130813-2	Zfish	PMID:30031069
Biological Process	GO:0001755	neural crest cell migration	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-130813-1	Zfish	PMID:23712262
Biological Process	GO:0021502	neural fold elevation formation	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:10328919
Biological Process	GO:0007405	neuroblast proliferation	Hif1a	IGI	MGI:MGI:103178	Mouse	PMID:17215402
Biological Process	GO:0051402	neuron apoptotic process	Hif1a	IMP	MGI:MGI:2677899	Mouse	PMID:12972594
Biological Process	GO:0051402	neuron apoptotic process	hif1ab	IGI	ZFIN:ZDB-MRPHLNO-100414-7,ZFIN:ZDB-MRPHLNO-100414-8,ZFIN:ZDB-MRPHLNO-100610-11	Zfish	PMID:19123687
Biological Process	GO:0007219	Notch signaling pathway	hif1aa	IMP	ZFIN:ZDB-GENO-171116-6	Zfish	PMID:29339404
Biological Process	GO:0007219	Notch signaling pathway	hif1ab	IMP	ZFIN:ZDB-GENO-171116-6	Zfish	PMID:29339404
Biological Process	GO:0007219	Notch signaling pathway	hif1aa	IGI	ZFIN:ZDB-GENE-040426-706	Zfish	PMID:29339404
Biological Process	GO:0007219	Notch signaling pathway	hif1ab	IGI	ZFIN:ZDB-GENE-080917-55	Zfish	PMID:29339404
Biological Process	GO:0003151	outflow tract morphogenesis	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:9436976
Biological Process	GO:0045766	positive regulation of angiogenesis	HIF1A	IMP		Human	PMID:24048733
Biological Process	GO:0045766	positive regulation of angiogenesis	HIF1A	IMP		Human	PMID:26879375
Biological Process	GO:0043065	positive regulation of apoptotic process	Hif1a	IMP		Rat	PMID:20224844|RGD:5147882
Biological Process	GO:0010508	positive regulation of autophagy	Hif1a	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	Hif1a	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	HIF1A	IMP		Human	PMID:26879375
Biological Process	GO:0008284	positive regulation of cell population proliferation	Hif1a	IMP		Rat	PMID:11029639|RGD:2301215
Biological Process	GO:0045793	positive regulation of cell size	Hif1a	IEP		Rat	PMID:22129453|RGD:9068885
Biological Process	GO:0070101	positive regulation of chemokine-mediated signaling pathway	HIF1A	IDA		Human	PMID:17178876
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	HIF1A	IDA		Human	PMID:32697943
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HIF1A	IMP		Human	PMID:21056661
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HIF1A	IDA		Human	PMID:25043030
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HIF1A	IDA		Human	PMID:9887100
Biological Process	GO:0010595	positive regulation of endothelial cell migration	Hif1a	IMP		Rat	PMID:30052311|RGD:155663378
Biological Process	GO:0010634	positive regulation of epithelial cell migration	Hif1a	IMP		Mouse	MGI:MGI:3772289|PMID:18037992
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:16787915
Biological Process	GO:0010628	positive regulation of gene expression	HIF1A	IDA		Human	PMID:15459207
Biological Process	GO:0010628	positive regulation of gene expression	HIF1A	IMP		Human	PMID:21817107
Biological Process	GO:0010628	positive regulation of gene expression	HIF1A	IMP		Human	PMID:22886504
Biological Process	GO:0010628	positive regulation of gene expression	HIF1A	IDA		Human	PMID:24244340
Biological Process	GO:0010628	positive regulation of gene expression	Hif1a	IMP		Rat	PMID:19220706|RGD:9068456
Biological Process	GO:0010628	positive regulation of gene expression	Hif1a	IMP		Rat	PMID:23485012|RGD:13506273
Biological Process	GO:0045722	positive regulation of gluconeogenesis	Hif1a	IMP		Rat	PMID:24177414|RGD:10445837
Biological Process	GO:0046886	positive regulation of hormone biosynthetic process	HIF1A	IDA		Human	PMID:1448077
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Hif1a	IMP	MGI:MGI:2677892	Mouse	PMID:20440072
Biological Process	GO:0016239	positive regulation of macroautophagy	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:19273585
Biological Process	GO:1902895	positive regulation of miRNA transcription	HIF1A	IMP		Human	PMID:19141645
Biological Process	GO:1902895	positive regulation of miRNA transcription	HIF1A	IDA		Human	PMID:19782034
Biological Process	GO:1902895	positive regulation of miRNA transcription	HIF1A	IMP		Human	PMID:24983504
Biological Process	GO:1902895	positive regulation of miRNA transcription	HIF1A	IMP		Human	PMID:33108349
Biological Process	GO:1902895	positive regulation of miRNA transcription	Hif1a	IMP		Mouse	MGI:MGI:6430928|PMID:25587068
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Hif1a	IGI	MGI:MGI:103178	Mouse	PMID:17215402
Biological Process	GO:2000273	positive regulation of signaling receptor activity	HIF1A	IMP		Human	PMID:17178876
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Hif1a	IMP		Rat	PMID:16489407|RGD:1626319
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	Hif1a	IMP		Rat	PMID:30052311|RGD:155663378
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIF1A	IGI	UniProtKB:Q9P0U3	Human	PMID:17981124
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIF1A	IDA		Human	PMID:11573933
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIF1A	IMP		Human	PMID:24048733
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIF1A	IDA		Human	PMID:32697943
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIF1A	IDA		Human	PMID:7539918
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIF1A	IDA		Human	PMID:8089148
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IDA		Mouse	MGI:MGI:5528778|PMID:24011070
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IDA		Mouse	PMID:24030251
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:17284606
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IGI	MGI:MGI:97856	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IGI	MGI:MGI:88071	Mouse	PMID:9113979
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IGI	MGI:MGI:97858	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IMP		Mouse	PMID:21856340
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IDA		Mouse	PMID:8702901
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IGI	MGI:MGI:97857	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IGI	MGI:MGI:88071	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IDA		Rat	PMID:11237857|RGD:68201
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hif1a	IMP		Rat	PMID:20496369|RGD:5147880
Biological Process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	HIF1A	IMP		Human	PMID:19652095
Biological Process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	HIF1A	IDA		Human	PMID:22735262
Biological Process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	HIF1A	IMP		Human	PMID:24681946
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	HIF1A	IMP		Human	PMID:18658046
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	HIF1A	IDA		Human	PMID:8756616
Biological Process	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	Hif1a	IMP	MGI:MGI:2386649,MGI:MGI:2386679	Mouse	PMID:11691837
Biological Process	GO:0035470	positive regulation of vascular wound healing	Hif1a	IMP		Rat	PMID:30052311|RGD:155663378
Biological Process	GO:1903715	regulation of aerobic respiration	Hif1a	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0045765	regulation of angiogenesis	hif1ab	IGI	ZFIN:ZDB-GENE-080917-55	Zfish	PMID:28524872
Biological Process	GO:0045765	regulation of angiogenesis	hif1aa	IGI	ZFIN:ZDB-GENE-040426-706	Zfish	PMID:28524872
Biological Process	GO:0050790	regulation of catalytic activity	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15328538
Biological Process	GO:0042127	regulation of cell population proliferation	Hif1a	IMP		Mouse	PMID:17437992
Biological Process	GO:1900037	regulation of cellular response to hypoxia	Hif1a	IEP		Rat	PMID:18054269|RGD:9068899
Biological Process	GO:0006355	regulation of DNA-templated transcription	HIF1A	IDA		Human	PMID:11782478
Biological Process	GO:0006355	regulation of DNA-templated transcription	HIF1A	IDA		Human	PMID:15261140
Biological Process	GO:0006355	regulation of DNA-templated transcription	Hif1a	IDA		Mouse	PMID:15456877
Biological Process	GO:0006355	regulation of DNA-templated transcription	hif1ab	IDA		Zfish	PMID:24613356
Biological Process	GO:0010468	regulation of gene expression	HIF1A	IDA		Human	PMID:18419598
Biological Process	GO:0010468	regulation of gene expression	HIF1A	IDA		Human	PMID:32697943
Biological Process	GO:0010468	regulation of gene expression	Hif1a	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0006110	regulation of glycolytic process	HIF1A	IDA		Human	PMID:32697943
Biological Process	GO:0006110	regulation of glycolytic process	Hif1a	IGI	MGI:MGI:96552	Mouse	PMID:17437992
Biological Process	GO:2000434	regulation of protein neddylation	HIF1A	IMP		Human	PMID:23401859
Biological Process	GO:0070243	regulation of thymocyte apoptotic process	Hif1a	IGI	MGI:MGI:103223	Mouse	PMID:15456877
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	HIF1A	IDA		Human	PMID:8089148
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	HIF1A	IDA		Human	PMID:8387214
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Hif1a	IMP	MGI:MGI:2385358	Mouse	PMID:12832481
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Hif1a	IMP		Rat	PMID:18614764|RGD:2301848
Biological Process	GO:0032909	regulation of transforming growth factor beta2 production	HIF1A	IMP		Human	PMID:12411310
Biological Process	GO:0014823	response to activity	Hif1a	IEP		Rat	PMID:19913571|RGD:9068915
Biological Process	GO:0043279	response to alkaloid	Hif1a	IEP		Rat	PMID:15067214|RGD:9068460
Biological Process	GO:0072347	response to anesthetic	Hif1a	IEP		Rat	PMID:18218685|RGD:9068462
Biological Process	GO:0010996	response to auditory stimulus	Hif1a	IEP		Rat	PMID:19840840|RGD:9068904
Biological Process	GO:0032025	response to cobalt ion	Hif1a	IEP		Rat	PMID:19384568|RGD:9068898
Biological Process	GO:0032355	response to estradiol	Hif1a	IEP		Rat	PMID:17716391|RGD:9068880
Biological Process	GO:0043627	response to estrogen	Hif1a	IEP		Rat	PMID:20487002|RGD:5147881
Biological Process	GO:0060992	response to fungicide	Hif1a	IMP		Rat	PMID:18347136|RGD:9068920
Biological Process	GO:0051384	response to glucocorticoid	Hif1a	IEP		Rat	PMID:18385541|RGD:9068478
Biological Process	GO:0009749	response to glucose	Hif1a	IEP		Rat	PMID:12189448|RGD:1626327
Biological Process	GO:0009749	response to glucose	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-081120-4	Zfish	PMID:23341543
Biological Process	GO:0001666	response to hypoxia	HIF1A	IDA		Human	PMID:11782478
Biological Process	GO:0001666	response to hypoxia	HIF1A	IMP		Human	PMID:12411310
Biological Process	GO:0001666	response to hypoxia	HIF1A	IDA		Human	PMID:15261140
Biological Process	GO:0001666	response to hypoxia	HIF1A	IDA		Human	PMID:18419598
Biological Process	GO:0001666	response to hypoxia	HIF1A	IDA		Human	PMID:8756616
Biological Process	GO:0001666	response to hypoxia	HIF1A	IDA		Human	PMID:9887100
Biological Process	GO:0001666	response to hypoxia	Hif1a	IMP		Mouse	MGI:MGI:6430928|PMID:25587068
Biological Process	GO:0001666	response to hypoxia	Hif1a	IMP	MGI:MGI:2385358	Mouse	PMID:9606183
Biological Process	GO:0001666	response to hypoxia	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:10074486
Biological Process	GO:0001666	response to hypoxia	Hif1a	IGI	MGI:MGI:96552	Mouse	PMID:17437992
Biological Process	GO:0001666	response to hypoxia	Hif1a	IDA		Mouse	PMID:8702901
Biological Process	GO:0001666	response to hypoxia	Hif1a	IMP	MGI:MGI:1857719	Mouse	PMID:11792862
Biological Process	GO:0001666	response to hypoxia	Hif1a	IDA		Mouse	PMID:11801735
Biological Process	GO:0001666	response to hypoxia	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:19273585
Biological Process	GO:0001666	response to hypoxia	Hif1a	IDA		Rat	PMID:12388599|RGD:628389
Biological Process	GO:0001666	response to hypoxia	Hif1a	IDA		Rat	PMID:12675925|RGD:632652
Biological Process	GO:0001666	response to hypoxia	hif1ab	IEP		Zfish	PMID:21343420
Biological Process	GO:0001666	response to hypoxia	hif1ab	IMP	ZFIN:ZDB-MRPHLNO-170222-1	Zfish	PMID:27802147
Biological Process	GO:0010039	response to iron ion	HIF1A	IEP		Human	PMID:28296633
Biological Process	GO:0009612	response to mechanical stimulus	Hif1a	IEP		Rat	PMID:21106323|RGD:5147878
Biological Process	GO:0014850	response to muscle activity	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:15328538
Biological Process	GO:0014074	response to purine-containing compound	Hif1a	IEP		Rat	PMID:18248612|RGD:9068884
Biological Process	GO:0000302	response to reactive oxygen species	HIF1A	IDA		Human	PMID:32697943
Biological Process	GO:0009651	response to salt stress	Hif1a	IEP		Rat	PMID:20232302|RGD:4889915
Biological Process	GO:0010165	response to X-ray	Hif1a	IEP		Rat	PMID:15161688|RGD:9068912
Biological Process	GO:0009410	response to xenobiotic stimulus	Hif1a	IEP		Rat	PMID:14574457|RGD:8694467
Biological Process	GO:0061298	retina vasculature development in camera-type eye	Hif1a	IMP	MGI:MGI:2386679	Mouse	PMID:21212189
Biological Process	GO:0007165	signal transduction	HIF1A	IMP		Human	PMID:12411310
Biological Process	GO:0031929	TOR signaling	Hif1a	IMP	MGI:MGI:2384429	Mouse	PMID:20808783
Biological Process	GO:0010573	vascular endothelial growth factor production	HIF1A	IDA		Human	PMID:12958148
Biological Process	GO:0001944	vasculature development	Hif1a	IGI	MGI:MGI:1306784	Mouse	PMID:18653562
Biological Process	GO:0008542	visual learning	Hif1a	IMP	MGI:MGI:2677899	Mouse	PMID:12972594

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern