Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIF1AN
  • Mouse genes Hif1an
  • Rat genes Hif1an
  • Zfish genes hif1an
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hif1an

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036140	[protein]-asparagine 3-dioxygenase activity	HIF1AN	IDA		Human	PMID:12080085
Molecular Function	GO:0036140	[protein]-asparagine 3-dioxygenase activity	HIF1AN	IDA		Human	PMID:12215170
Molecular Function	GO:0036140	[protein]-asparagine 3-dioxygenase activity	HIF1AN	IDA		Human	PMID:14734545
Molecular Function	GO:0036140	[protein]-asparagine 3-dioxygenase activity	HIF1AN	IMP		Human	PMID:19245366
Molecular Function	GO:0036140	[protein]-asparagine 3-dioxygenase activity	HIF1AN	IDA		Human	PMID:21177872
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:P25963	Human	PMID:17003112
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:Q9BZF9	Human	PMID:17003112
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:Q9UK73	Human	PMID:17003112
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:Q9WV71	Human	PMID:17636018
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:P16157	Human	PMID:21177872
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:Q01484	Human	PMID:21177872
Molecular Function	GO:0071532	ankyrin repeat binding	HIF1AN	IPI	UniProtKB:Q9H2K2	Human	PMID:21251231
Molecular Function	GO:0031406	carboxylic acid binding	HIF1AN	IDA		Human	PMID:17135241
Molecular Function	GO:0008198	ferrous iron binding	HIF1AN	IDA		Human	PMID:12446723
Molecular Function	GO:0051059	NF-kappaB binding	HIF1AN	IPI	UniProtKB:P19838	Human	PMID:17003112
Molecular Function	GO:0005112	Notch binding	HIF1AN	IPI	UniProtKB:O35516	Human	PMID:17573339
Molecular Function	GO:0005112	Notch binding	HIF1AN	IPI	UniProtKB:Q61982	Human	PMID:17573339
Molecular Function	GO:0005112	Notch binding	HIF1AN	IPI	UniProtKB:Q01705	Human	PMID:18299578
Molecular Function	GO:0062101	peptidyl-aspartic acid 3-dioxygenase activity	HIF1AN	IDA		Human	PMID:21177872
Molecular Function	GO:0036139	peptidyl-histidine dioxygenase activity	HIF1AN	IDA		Human	PMID:21251231
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O15379	Human	PMID:11641274
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P40337	Human	PMID:11641274
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q13547	Human	PMID:11641274
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:11641274
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q92769	Human	PMID:11641274
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:12446723
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q96DX5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O75832	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O95271	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P19838	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P25963	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q13418	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q8WVL7	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9BZF9	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9UK73	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q01705	Human	PMID:17573339
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q96DX5	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:19071119
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O96018	Human	PMID:19726677
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O95271	Human	PMID:21251231
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9H2K2	Human	PMID:21251231
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P19838	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:26751287
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:26752685
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q96FW1	Human	PMID:26752685
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O96018	Human	PMID:26948053
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O75832	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O95271	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P25963	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P57078	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q13418	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q16665	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9H2K2	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O95271	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O96018	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:P25963	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q8WVL7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q96DX5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q96FW1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9H2K2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:O96018	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q8WVL7	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q96DX5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q6PG48	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q7Z713	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q8NFD2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9H672-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q9ULJ7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIF1AN	IPI	UniProtKB:Q8NFD2	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Hif1an	IPI	UniProtKB:Q9CZK6	Mouse	MGI:MGI:5621197|PMID:25671767
Molecular Function	GO:0042803	protein homodimerization activity	HIF1AN	IDA		Human	PMID:12446723
Molecular Function	GO:0008270	zinc ion binding	HIF1AN	IDA		Human	PMID:12446723
Cellular Component	GO:0005737	cytoplasm	HIF1AN	IDA		Human	PMID:14734545
Cellular Component	GO:0005829	cytosol	HIF1AN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HIF1AN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HIF1AN	IDA		Human	PMID:18299578
Cellular Component	GO:0048471	perinuclear region of cytoplasm	HIF1AN	IDA		Human	PMID:19726677
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	HIF1AN	IDA		Human	PMID:11641274
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	HIF1AN	IDA		Human	PMID:12080085
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	HIF1AN	IDA		Human	PMID:18299578
Biological Process	GO:1901343	negative regulation of vasculature development	hif1an	IDA		Zfish	PMID:25347788
Biological Process	GO:1901343	negative regulation of vasculature development	hif1an	IMP	ZFIN:ZDB-MRPHLNO-150205-3	Zfish	PMID:25347788
Biological Process	GO:0045663	positive regulation of myoblast differentiation	HIF1AN	IMP		Human	PMID:18299578
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	hif1an	IGI	ZFIN:ZDB-GENE-990415-273	Zfish	PMID:25347788
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	hif1an	IGI	ZFIN:ZDB-GENE-030826-19	Zfish	PMID:25347788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern