Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIGD1A
  • Mouse genes Higd1a
  • Rat genes Higd1a
  • Zfish genes higd1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Higd1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0016020	membrane	Higd1a	IDA		Mouse	PMID:16815968
Cellular Component	GO:0005743	mitochondrial inner membrane	Higd1a	IDA		Mouse	PMID:16815968
Cellular Component	GO:0005739	mitochondrion	HIGD1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Higd1a	IDA		Mouse	MGI:MGI:5619730|PMID:23646141
Cellular Component	GO:0005739	mitochondrion	Higd1a	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Higd1a	IDA		Mouse	PMID:21856340
Cellular Component	GO:0005654	nucleoplasm	HIGD1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Higd1a	IDA		Mouse	MGI:MGI:5619730|PMID:23646141
Cellular Component	GO:0032991	protein-containing complex	HIGD1A	IDA		Human	GO_REF:0000054
Biological Process	GO:0042149	cellular response to glucose starvation	Higd1a	IMP		Mouse	PMID:25683712
Biological Process	GO:0042149	cellular response to glucose starvation	Higd1a	IDA		Mouse	PMID:16815968
Biological Process	GO:0071456	cellular response to hypoxia	Higd1a	IMP		Mouse	PMID:25683712
Biological Process	GO:0071456	cellular response to hypoxia	Higd1a	IDA		Mouse	PMID:21856340
Biological Process	GO:0071456	cellular response to hypoxia	Higd1a	IDA		Mouse	PMID:16815968
Biological Process	GO:0043066	negative regulation of apoptotic process	HIGD1A	IDA		Human	PMID:21856340
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	Higd1a	IDA		Mouse	PMID:21856340
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	Higd1a	IMP		Mouse	PMID:25683712

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern