Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIP1
  • Mouse genes Hip1
  • Rat genes Hip1
  • Zfish genes hip1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	HIP1	IDA		Human	PMID:18790740
Molecular Function	GO:0035612	AP-2 adaptor complex binding	HIP1	IPI	UniProtKB:P63010	Human	PMID:15533940
Molecular Function	GO:0030276	clathrin binding	HIP1	IDA		Human	PMID:11577110
Molecular Function	GO:0030276	clathrin binding	HIP1	IDA		Human	PMID:14732715
Molecular Function	GO:0030276	clathrin binding	Hip1	IDA		Rat	PMID:11889126|RGD:708337
Molecular Function	GO:0032051	clathrin light chain binding	HIP1	IPI	UniProtKB:P04973	Human	PMID:15533940
Molecular Function	GO:0032051	clathrin light chain binding	HIP1	IPI	UniProtKB:P04975	Human	PMID:15533940
Molecular Function	GO:0032051	clathrin light chain binding	HIP1	IPI	UniProtKB:P04975	Human	PMID:18790740
Molecular Function	GO:0035091	phosphatidylinositol binding	HIP1	IDA		Human	PMID:14732715
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	HIP1	IDA		Human	PMID:14732715
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	HIP1	IDA		Human	PMID:14732715
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	HIP1	IDA		Human	PMID:14732715
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9NWB7	Human	PMID:11788820
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:O75146	Human	PMID:11889126
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P09497	Human	PMID:11889126
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P42858	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P10275	Human	PMID:16027218
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9EPV5	Human	PMID:16979168
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9CR95	Human	PMID:17762867
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P42858	Human	PMID:22835334
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q15038	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q15038	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P54727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8N8B7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q92567-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q96M91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q99732	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9BSW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9NUQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9UI32	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:O00257-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:O15273	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:O43548	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:O43829	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:O60506-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P02458-1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P09496-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P22307-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P34949-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P35222	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P36406	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P36639-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P42773	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P47804-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:P54274-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q06547-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q09028	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q13573	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q13901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q14032	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q15382	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q15393	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q15742-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q16609	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q3SXR2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q49A26-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q53FD0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q5JTY5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q5W111-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q6N063-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q86US8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8IWT0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8IYG6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8IZU1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8N0X7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8N4N3-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8N5U6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8N5Z5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8NA23-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8NCQ7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8NDH3-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8WUD1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q8WZ55	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q96A09	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q96BD6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q96EW2-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q96KS9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q96MA6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q99732	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9BPU6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9BZQ2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9H0Y0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9H2C1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9NQ88	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9NSI6-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9P1Q0-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9P2T0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9UK76	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9UKG9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9Y303-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9Y614	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HIP1	IPI	UniProtKB:Q9NWB7	Human	PMID:9140394
Molecular Function	GO:0005515	protein binding	Hip1	IPI	UniProtKB:P23818	Mouse	MGI:MGI:2667266|PMID:12839988
Molecular Function	GO:0005515	protein binding	Hip1	IPI	UniProtKB:P35436|UniProtKB:Q01097	Mouse	MGI:MGI:3703280|PMID:17329427
Molecular Function	GO:0046982	protein heterodimerization activity	HIP1	IPI	UniProtKB:Q9JKY5	Human	PMID:15533940
Molecular Function	GO:0042803	protein homodimerization activity	HIP1	IDA		Human	PMID:15533940
Molecular Function	GO:0042803	protein homodimerization activity	HIP1	IDA		Human	PMID:18790740
Cellular Component	GO:0030136	clathrin-coated vesicle	HIP1	IDA		Human	PMID:11517213
Cellular Component	GO:0030136	clathrin-coated vesicle	Hip1	IDA		Rat	PMID:11889126|RGD:708337
Cellular Component	GO:0005737	cytoplasm	HIP1	IDA		Human	PMID:11604514
Cellular Component	GO:0098978	glutamatergic synapse	Hip1	IDA		Mouse	PMID:12839988
Cellular Component	GO:0098978	glutamatergic synapse	Hip1	IPI		Mouse	PMID:12839988
Cellular Component	GO:0098978	glutamatergic synapse	Hip1	IMP		Mouse	PMID:12839988
Cellular Component	GO:0098978	glutamatergic synapse	Hip1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0005794	Golgi apparatus	HIP1	IDA		Human	PMID:11788820
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	HIP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Hip1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0098794	postsynapse	Hip1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0045211	postsynaptic membrane	Hip1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0098793	presynapse	HIP1	IDA		Human	PMID:20074057
Cellular Component	GO:0098793	presynapse	Hip1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0042734	presynaptic membrane	Hip1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Hip1	IDA		Mouse	PMID:17928447
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Hip1	IMP		Mouse	PMID:17928447
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	HIP1	IDA		Human	PMID:11788820
Biological Process	GO:0006915	apoptotic process	HIP1	IDA		Human	PMID:11788820
Biological Process	GO:0097190	apoptotic signaling pathway	HIP1	IDA		Human	PMID:11007801
Biological Process	GO:0043009	chordate embryonic development	hip1	IMP	ZFIN:ZDB-MRPHLNO-100428-4	Zfish	PMID:20146355
Biological Process	GO:0043009	chordate embryonic development	hip1	IMP	ZFIN:ZDB-MRPHLNO-100428-3	Zfish	PMID:20146355
Biological Process	GO:0048268	clathrin coat assembly	HIP1	IDA		Human	PMID:11577110
Biological Process	GO:0048268	clathrin coat assembly	HIP1	IDA		Human	PMID:11889126
Biological Process	GO:0048268	clathrin coat assembly	Hip1	IDA		Rat	PMID:11889126|RGD:708337
Biological Process	GO:0006897	endocytosis	Hip1	IDA		Mouse	MGI:MGI:2153333|PMID:11604514
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	HIP1	IMP		Human	PMID:14732715
Biological Process	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	HIP1	IMP		Human	PMID:14732715
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	HIP1	IMP		Human	PMID:11532990
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	HIP1	IMP		Human	PMID:11577110
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	Hip1	IMP		Mouse	MGI:MGI:2154594|PMID:11577110
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Hip1	IDA		Mouse	PMID:17928447
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Hip1	IMP		Mouse	PMID:17928447
Biological Process	GO:0050821	protein stabilization	HIP1	IDA		Human	PMID:14732715
Biological Process	GO:0042981	regulation of apoptotic process	HIP1	IDA		Human	PMID:11788820
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hip1	IMP		Mouse	PMID:12839988
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hip1	IDA		Mouse	PMID:12839988
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hip1	IPI		Mouse	PMID:12839988
Biological Process	GO:0001878	response to yeast	hip1	IDA		Zfish	PMID:23947337

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern