Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIPK1
  • Mouse genes Hipk1
  • Rat genes Hipk1
  • Zfish genes hipk1a,hipk1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hipk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HIPK1	IPI	UniProtKB:P04637	Human	PMID:12702766
Molecular Function	GO:0005515	protein binding	HIPK1	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HIPK1	IPI	UniProtKB:Q13643	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Hipk1	IPI	UniProtKB:O35613|UniProtKB:Q9UER7	Mouse	MGI:MGI:2449749|PMID:12529400
Molecular Function	GO:0005515	protein binding	Hipk1	IPI	UniProtKB:Q9ERH7	Mouse	MGI:MGI:1913166|PMID:11034606
Molecular Function	GO:0005515	protein binding	Hipk1	IPI	PR:P23804	Mouse	PMID:22173032
Cellular Component	GO:0005813	centrosome	HIPK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	HIPK1	IDA		Human	PMID:15701637
Cellular Component	GO:0005737	cytoplasm	HIPK1	IDA		Human	PMID:28289210
Cellular Component	GO:0005737	cytoplasm	Hipk1	IDA		Mouse	MGI:MGI:4818711|PMID:20579985
Cellular Component	GO:0005737	cytoplasm	Hipk1	IDA		Mouse	PMID:12529400
Cellular Component	GO:0005829	cytosol	HIPK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	Hipk1	IDA		Mouse	PMID:12529400
Cellular Component	GO:0005654	nucleoplasm	HIPK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HIPK1	IDA		Human	PMID:15701637
Cellular Component	GO:0005634	nucleus	HIPK1	IDA		Human	PMID:28289210
Cellular Component	GO:0016605	PML body	Hipk1	IDA		Mouse	PMID:12529400
Biological Process	GO:0034333	adherens junction assembly	Hipk1	IMP		Mouse	MGI:MGI:5494340|PMID:23565059
Biological Process	GO:0009952	anterior/posterior pattern specification	Hipk1	IGI	MGI:MGI:1314872	Mouse	PMID:16537918
Biological Process	GO:0008283	cell population proliferation	Hipk1	IGI	MGI:MGI:1314872	Mouse	PMID:16537918
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	Hipk1	IMP		Mouse	MGI:MGI:4818711|PMID:20579985
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	Hipk1	IMP		Mouse	MGI:MGI:4818711|PMID:20579985
Biological Process	GO:0072577	endothelial cell apoptotic process	HIPK1	IDA		Human	PMID:15701637
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	HIPK1	IDA		Human	PMID:15701637
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Hipk1	IGI	MGI:MGI:1314872	Mouse	PMID:16537918
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Hipk1	IGI	MGI:MGI:98834	Mouse	PMID:16537918
Biological Process	GO:0061072	iris morphogenesis	Hipk1	IMP		Mouse	MGI:MGI:4818711|PMID:20579985
Biological Process	GO:0060235	lens induction in camera-type eye	Hipk1	IMP		Mouse	MGI:MGI:4818711|PMID:20579985
Biological Process	GO:0030182	neuron differentiation	Hipk1	IMP		Mouse	MGI:MGI:4818711|PMID:20579985
Biological Process	GO:0008284	positive regulation of cell population proliferation	Hipk1	IGI	MGI:MGI:1314872	Mouse	PMID:16537918
Biological Process	GO:0006468	protein phosphorylation	HIPK1	IDA		Human	PMID:24559171
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	HIPK1	IDA		Human	PMID:15701637
Biological Process	GO:0010842	retina layer formation	Hipk1	IMP		Mouse	MGI:MGI:4818711|PMID:20579985
Biological Process	GO:0007224	smoothened signaling pathway	Hipk1	IGI	MGI:MGI:1314872	Mouse	PMID:16537918

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern