Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIPK3
  • Mouse genes Hipk3
  • Rat genes Hipk3
  • Zfish genes hipk3a,hipk3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hipk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Hipk3	IPI	UniProtKB:O88904|UniProtKB:P25446	Mouse	MGI:MGI:1913166|PMID:11034606
Molecular Function	GO:0005515	protein binding	Hipk3	IPI	UniProtKB:P25446	Mouse	MGI:MGI:1913166|PMID:11034606
Molecular Function	GO:0004672	protein kinase activity	HIPK3	IDA		Human	PMID:14766760
Molecular Function	GO:0004674	protein serine/threonine kinase activity	HIPK3	IDA		Human	PMID:10919273
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Hipk3	IDA		Mouse	MGI:MGI:1913166|PMID:11034606
Cellular Component	GO:0005737	cytoplasm	Hipk3	IDA		Mouse	MGI:MGI:1913166|PMID:11034606
Cellular Component	GO:0005829	cytosol	HIPK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	HIPK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	HIPK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016605	PML body	Hipk3	IDA		Mouse	MGI:MGI:1913166|PMID:11034606
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	hipk3a	IDA		Zfish	PMID:18618001
Biological Process	GO:0009299	mRNA transcription	HIPK3	IDA		Human	PMID:17210646
Biological Process	GO:0043066	negative regulation of apoptotic process	HIPK3	IMP		Human	PMID:14766760
Biological Process	GO:0043508	negative regulation of JUN kinase activity	Hipk3	IMP		Mouse	MGI:MGI:1913166|PMID:11034606
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Hipk3	IDA		Mouse	MGI:MGI:1913166|PMID:11034606
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Hipk3	IDA		Mouse	MGI:MGI:1913166|PMID:11034606
Biological Process	GO:0006468	protein phosphorylation	HIPK3	IDA		Human	PMID:14766760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern