Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIVEP1
  • Mouse genes Hivep1
  • Rat genes Hivep1
  • Zfish genes hivep1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hivep1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Hivep1	IDA		Mouse	PMID:15778499
Molecular Function	GO:0003677	DNA binding	Hivep1	IDA		Rat	PMID:1901405|RGD:1299569
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Hivep1	IDA		Mouse	MGI:MGI:3584225|PMID:15778499
Molecular Function	GO:0071837	HMG box domain binding	Hivep1	IPI	UniProtKB:O55170	Mouse	MGI:MGI:5284787|PMID:16582099
Molecular Function	GO:0005515	protein binding	HIVEP1	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	HIVEP1	IPI	UniProtKB:Q969X6	Human	PMID:19732766
Molecular Function	GO:0005515	protein binding	HIVEP1	IPI	UniProtKB:O00555	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	HIVEP1	IPI	UniProtKB:P54253	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	Hivep1	IPI	UniProtKB:P63085	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hivep1	IDA		Mouse	MGI:MGI:3584225|PMID:15778499
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Hivep1	IDA		Mouse	PMID:10825206
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HIVEP1	IDA		Human	PMID:2106471
Cellular Component	GO:0005829	cytosol	HIVEP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	HIVEP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	HIVEP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HIVEP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HIVEP1	IDA		Human	PMID:19732766
Cellular Component	GO:0005634	nucleus	Hivep1	IDA		Mouse	PMID:15778499
Biological Process	GO:0030509	BMP signaling pathway	HIVEP1	IDA		Human	PMID:17008448
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hivep1	IDA		Mouse	PMID:15778499
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HIVEP1	IDA		Human	PMID:17008448
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hivep1	IDA		Mouse	MGI:MGI:3584225|PMID:15778499
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hivep1	IDA		Mouse	PMID:10825206
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hivep1	IGI	MGI:MGI:98371	Mouse	PMID:10825206
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HIVEP1	IDA		Human	PMID:17008448

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern