Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HK3
  • Mouse genes Hk3
  • Rat genes Hk3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Hk3	IPI	RGD:737496	Rat	PMID:11068878|RGD:2302674
Molecular Function	GO:0008865	fructokinase activity	Hk3	IDA		Rat	PMID:5871820|RGD:14695073
Molecular Function	GO:0004340	glucokinase activity	Hk3	IDA		Rat	PMID:5871820|RGD:14695073
Molecular Function	GO:0004396	hexokinase activity	HK3	IDA		Human	PMID:8717435
Molecular Function	GO:0004396	hexokinase activity	Hk3	IDA		Rat	PMID:15138155|RGD:1582633
Molecular Function	GO:0042562	hormone binding	Hk3	IPI	RGD:69123	Rat	PMID:11068878|RGD:2302674
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:P48643	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:P60891	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:Q86V38	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HK3	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hk3	IPI	RGD:1345254|RGD:69043|RGD:1347626	Rat	PMID:11068878|RGD:2302674
Cellular Component	GO:0005739	mitochondrion	Hk3	HDA		Mouse	PMID:18614015
Cellular Component	GO:0032991	protein-containing complex	Hk3	IDA		Rat	PMID:11068878|RGD:2302674
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	Hk3	IDA		Rat	PMID:5871820|RGD:14695073
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	Hk3	IDA		Rat	PMID:5871820|RGD:14695073
Biological Process	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death	Hk3	IDA		Rat	PMID:21072205|RGD:10047370

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern