Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HMBOX1
  • Mouse genes Hmbox1
  • Rat genes Hmbox1
  • Zfish genes hmbox1a,hmbox1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hmbox1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	HMBOX1	IDA		Human	PMID:23685356
Molecular Function	GO:0042802	identical protein binding	HMBOX1	IPI	UniProtKB:Q6NT76	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	HMBOX1	IPI	UniProtKB:Q6NT76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O60832	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P12956	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P13010	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P38432	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NPE3	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NX24	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NY12	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:A0AVT1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:E9PJI5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O43167	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O75553	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O95363	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P08579	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P32969	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P48047	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P51959	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P54646	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P55081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P78356	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q13084	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q13131	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q13895	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q15906	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q3B820	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q5TZK3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q6ZN18-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8N8B7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8NE31	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8TAU3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q92993	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96FJ2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96HR9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96NC0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96NE9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96SQ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9BVV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H213	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H257	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H672	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H7E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H832	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9HAJ7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9HC52	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NX38	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9P0T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9UBU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9Y3B7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9Y3M9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:A0A0S2Z5X4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96FJ2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:A0A384ME17	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:A1A5B0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O00311	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O94829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:O95696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P15622-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P19544-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P25800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P26368-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P32969	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P55081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P62851	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:P63167	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q02548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q07002	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q13573	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q13895	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q15014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q32MN6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q3B820	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q53HL2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q5SQQ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q5T7P8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q68DK2-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q6ZN18-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8IVT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8N7W2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8NHY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q8WUT1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q92914	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q92993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q99633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9C086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H147	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H672-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H788	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9H7E9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9HAQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9HC52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9HCK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NTX9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NVN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9NX38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9P0T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9P2K3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9UBU8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9UGP5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9UIF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMBOX1	IPI	UniProtKB:Q9UJ78-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hmbox1	IPI	UniProtKB:P23475|UniProtKB:P27641	Mouse	MGI:MGI:5500098|PMID:23685356
Molecular Function	GO:0005515	protein binding	Hmbox1	IPI	UniProtKB:Q5SU73|UniProtKB:Q9CQS2|UniProtKB:Q9CRB2|UniProtKB:Q9CY66|UniProtKB:Q9ESX5	Mouse	MGI:MGI:5500098|PMID:23685356
Molecular Function	GO:0044877	protein-containing complex binding	HMBOX1	IPI	ComplexPortal:CPX-1993	Human	PMID:23685356
Molecular Function	GO:0044877	protein-containing complex binding	Hmbox1	IPI	ComplexPortal:CPX-2047	Mouse	MGI:MGI:5500098|PMID:23685356
Molecular Function	GO:0043565	sequence-specific DNA binding	HMBOX1	IDA		Human	PMID:23332764
Molecular Function	GO:0043565	sequence-specific DNA binding	HMBOX1	IDA		Human	PMID:28473536
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HMBOX1	IDA		Human	PMID:28473536
Molecular Function	GO:0042162	telomeric DNA binding	HMBOX1	IDA		Human	PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	HMBOX1	IMP		Human	PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	Hmbox1	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Cellular Component	GO:0005813	centrosome	HMBOX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000781	chromosome, telomeric region	HMBOX1	HDA		Human	PMID:19135898
Cellular Component	GO:0000781	chromosome, telomeric region	HMBOX1	IDA		Human	PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	Hmbox1	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Cellular Component	GO:0005737	cytoplasm	HMBOX1	IDA		Human	PMID:19757162
Cellular Component	GO:0005829	cytosol	HMBOX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	HMBOX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HMBOX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HMBOX1	IDA		Human	PMID:19757162
Cellular Component	GO:0005634	nucleus	Hmbox1	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HMBOX1	IDA		Human	PMID:19757162
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HMBOX1	IDA		Human	PMID:21839858
Biological Process	GO:0035563	positive regulation of chromatin binding	Hmbox1	IMP		Mouse	MGI:MGI:5500098|PMID:23685356
Biological Process	GO:0051973	positive regulation of telomerase activity	HMBOX1	IDA		Human	PMID:23685356
Biological Process	GO:0051973	positive regulation of telomerase activity	HMBOX1	IMP		Human	PMID:23685356
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	HMBOX1	IDA		Human	PMID:23685356
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	HMBOX1	IMP		Human	PMID:23685356
Biological Process	GO:0051972	regulation of telomerase activity	HMBOX1	IDA		Human	PMID:23685356

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern