Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HMCES
  • Mouse genes Hmces
  • Rat genes Hmces
  • Zfish genes hmces
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hmces

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HMCES	IPI	UniProtKB:P12004	Human	PMID:30554877
Molecular Function	GO:0003697	single-stranded DNA binding	HMCES	IDA		Human	PMID:30554877
Molecular Function	GO:0003697	single-stranded DNA binding	HMCES	IDA		Human	PMID:31235913
Molecular Function	GO:0003697	single-stranded DNA binding	Hmces	IDA		Mouse	MGI:MGI:6393148|PMID:31806351
Cellular Component	GO:0005657	replication fork	HMCES	IDA		Human	PMID:30554877
Biological Process	GO:0006974	DNA damage response	HMCES	IDA		Human	PMID:30554877
Biological Process	GO:0006974	DNA damage response	HMCES	IDA		Human	PMID:31235913
Biological Process	GO:0097681	double-strand break repair via alternative nonhomologous end joining	Hmces	IDA		Mouse	MGI:MGI:6393148|PMID:31806351
Biological Process	GO:0045830	positive regulation of isotype switching	Hmces	IDA		Mouse	MGI:MGI:6393148|PMID:31806351
Biological Process	GO:0018142	protein-DNA covalent cross-linking	HMCES	IDA		Human	PMID:30554877
Biological Process	GO:0018142	protein-DNA covalent cross-linking	HMCES	IDA		Human	PMID:31235913

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern