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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hmga1b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hmga1b
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0000987cis-regulatory region sequence-specific DNA bindingHMGA1IDAHumanPMID:9253416
Molecular FunctionGO:0003677DNA bindingHMGA1IDAHumanPMID:11069991
Molecular FunctionGO:0003677DNA bindingHMGA1IDAHumanPMID:15213251
Molecular FunctionGO:0003677DNA bindingHMGA1EXPHumanPMID:22615915
Molecular FunctionGO:0003677DNA bindingHMGA1EXPHumanPMID:9253416
Molecular FunctionGO:0008301DNA binding, bendingHMGA1EXPHumanPMID:22615915
Molecular FunctionGO:0019899enzyme bindingHMGA1IPIUniProtKB:Q96LA8HumanPMID:16157300
Molecular FunctionGO:0003680minor groove of adenine-thymine-rich DNA bindingHMGA1IDAHumanPMID:9253416
Molecular FunctionGO:0060090molecular adaptor activityHMGA1IDAHumanPMID:11069991
Molecular FunctionGO:0140677molecular function activator activityHMGA1IMPHumanPMID:21087998
Molecular FunctionGO:0030374nuclear receptor coactivator activityHMGA1IMPHumanPMID:10428834
Molecular FunctionGO:0042974nuclear retinoic acid receptor bindingHMGA1IDAHumanPMID:10428834
Molecular FunctionGO:0046965nuclear retinoid X receptor bindingHMGA1IDAHumanPMID:10428834
Molecular FunctionGO:0042975peroxisome proliferator activated receptor bindingHMGA1IDAHumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:P19838HumanPMID:10400641
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:O75798HumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:P05412HumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:P13631HumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:P19793HumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:P37231HumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:Q92793HumanPMID:10428834
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:Q9Y5N6HumanPMID:18234858
Molecular FunctionGO:0005515protein bindingHMGA1IPIUniProtKB:Q92793HumanPMID:9809067
Molecular FunctionGO:0003723RNA bindingHMGA1IPIRNAcentral:URS0000734D8F_9606HumanPMID:21087998
Molecular FunctionGO:0003713transcription coactivator activityHMGA1IMPHumanPMID:10428834
Molecular FunctionGO:0003713transcription coactivator activityHMGA1EXPHumanPMID:9253416
Molecular FunctionGO:0001221transcription coregulator bindingHMGA1IDAHumanPMID:10428834
Cellular ComponentGO:0005925focal adhesionHMGA1HDAHumanPMID:21423176
Cellular ComponentGO:0005634nucleusHMGA1HDAHumanPMID:16791210
Cellular ComponentGO:0005634nucleusHMGA1IDAHumanPMID:16901784
Cellular ComponentGO:0035985senescence-associated heterochromatin focusHMGA1IDAHumanPMID:16901784
Biological ProcessGO:0008285negative regulation of cell population proliferationHMGA1IMPHumanPMID:16901784
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionHMGA1IMPHumanPMID:16901784
Biological ProcessGO:0090402oncogene-induced cell senescenceHMGA1IDAHumanPMID:16901784
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionHMGA1IMPHumanPMID:10428834
Biological ProcessGO:0043484regulation of RNA splicinghmga1aIMPZFIN:ZDB-MRPHLNO-141211-4ZfishPMID:25814654

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory