Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HMGB3
  • Mouse genes Hmgb3
  • Rat genes Hmgb3
  • Zfish genes hmgb3a,hmgb3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hmgb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Hmgb3	IDA		Mouse	MGI:MGI:4367121|PMID:19890330
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:O00560	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:Q02548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HMGB3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	HMGB3	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Hmgb3	IDA		Mouse	MGI:MGI:4367121|PMID:19890330
Cellular Component	GO:0005634	nucleus	Hmgb3	IDA		Mouse	PMID:12714519
Biological Process	GO:0045578	negative regulation of B cell differentiation	Hmgb3	IDA		Mouse	PMID:12714519
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	Hmgb3	IDA		Mouse	PMID:12714519

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern