Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HNMT
  • Mouse genes Hnmt
  • Rat genes Hnmt
  • Zfish genes hnmt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hnmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046539	histamine N-methyltransferase activity	HNMT	IDA		Human	PMID:26206890
Molecular Function	GO:0046539	histamine N-methyltransferase activity	Hnmt	IDA		Rat	PMID:15739896|RGD:152985534
Molecular Function	GO:0046539	histamine N-methyltransferase activity	Hnmt	IDA		Rat	PMID:1639806|RGD:70763
Molecular Function	GO:0008170	N-methyltransferase activity	Hnmt	IDA		Mouse	PMID:11475331
Cellular Component	GO:0005813	centrosome	HNMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	HNMT	IDA		Human	PMID:26206890
Cellular Component	GO:0005829	cytosol	HNMT	IDA		Human	PMID:23505051
Cellular Component	GO:0005829	cytosol	HNMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Hnmt	IDA		Rat	PMID:15739896|RGD:152985534
Cellular Component	GO:0005829	cytosol	Hnmt	IDA		Rat	PMID:6415051|RGD:152985536
Cellular Component	GO:0070062	extracellular exosome	HNMT	HDA		Human	PMID:19056867
Cellular Component	GO:0043005	neuron projection	Hnmt	IDA		Rat	PMID:2717067|RGD:2316836
Cellular Component	GO:0005654	nucleoplasm	HNMT	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	Hnmt	IEP		Rat	PMID:971743|RGD:2316842
Biological Process	GO:0001695	histamine catabolic process	HNMT	IDA		Human	PMID:26206890
Biological Process	GO:0001692	histamine metabolic process	HNMT	IMP		Human	PMID:23505051
Biological Process	GO:0001692	histamine metabolic process	Hnmt	IDA		Rat	PMID:15739896|RGD:152985534
Biological Process	GO:0006972	hyperosmotic response	Hnmt	IEP		Rat	PMID:2429527|RGD:2316838
Biological Process	GO:0032259	methylation	HNMT	IDA		Human	PMID:26206890
Biological Process	GO:0014075	response to amine	Hnmt	IEP		Rat	PMID:3952132|RGD:2316841
Biological Process	GO:0042220	response to cocaine	Hnmt	IEP		Rat	PMID:9231750|RGD:2316833
Biological Process	GO:0051384	response to glucocorticoid	Hnmt	IEP		Rat	PMID:2717067|RGD:2316836
Biological Process	GO:0035902	response to immobilization stress	Hnmt	IEP		Rat	PMID:10203252|RGD:2316832
Biological Process	GO:0070555	response to interleukin-1	Hnmt	IEP		Rat	PMID:8594930|RGD:2316834
Biological Process	GO:0002347	response to tumor cell	Hnmt	IEP		Rat	PMID:3111198|RGD:2316837
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Hnmt	IDA		Rat	PMID:15739896|RGD:152985534

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern