Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HNRNPA1,HNRNPA1L2
  • Mouse genes Hnrnpa1
  • Rat genes Hnrnpa1
  • Zfish genes hnrnpa1a,hnrnpa1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hnrnpa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	HNRNPA1	EXP		Human	PMID:10323862
Molecular Function	GO:1990814	DNA/DNA annealing activity	Hnrnpa1	IDA		Rat	PMID:1703006|RGD:10045979
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	HNRNPA1	IDA		Human	PMID:23935072
Molecular Function	GO:0035198	miRNA binding	HNRNPA1	IDA		Human	PMID:28431233
Molecular Function	GO:0140693	molecular condensate scaffold activity	HNRNPA1	IDA		Human	PMID:33982369
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Hnrnpa1	IDA		Rat	PMID:11723238|RGD:10045969
Molecular Function	GO:0003730	mRNA 3'-UTR binding	hnrnpa1a	IDA		Zfish	PMID:31227602
Molecular Function	GO:0003729	mRNA binding	Hnrnpa1	IDA		Rat	PMID:23106379|RGD:10045574
Molecular Function	GO:0036002	pre-mRNA binding	HNRNPA1	IDA		Human	PMID:25689357
Molecular Function	GO:0036002	pre-mRNA binding	HNRNPA1	IDA		Human	PMID:28985503
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P07910	Human	PMID:11546873
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P27958:PRO_0000037577	Human	PMID:17229681
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q14141	Human	PMID:17229681
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q07666	Human	PMID:17371836
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q07666	Human	PMID:20186123
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P31942	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P07910	Human	PMID:22446626
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P31942	Human	PMID:22446626
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q07666	Human	PMID:24514149
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q96LT7	Human	PMID:24549040
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q9UHD9	Human	PMID:25616961
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P62937	Human	PMID:25678563
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P22626	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P31942	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P51991	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:Q07666	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:C0HLZ6	Human	PMID:28985503
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P07910	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P22626	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HNRNPA1	IPI	UniProtKB:P51991	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	Hnrnpa1	IPI	RGD:71058	Rat	PMID:16518874|RGD:10054427
Molecular Function	GO:0005515	protein binding	Hnrnpa1	IPI	RGD:628780	Rat	PMID:23159318|RGD:10040996
Molecular Function	GO:0005515	protein binding	Hnrnpa1	IPI	RGD:71058	Rat	PMID:23159318|RGD:10040996
Molecular Function	GO:0019904	protein domain specific binding	HNRNPA1	IPI	UniProtKB:P0DJD4	Human	PMID:10332027
Molecular Function	GO:0019904	protein domain specific binding	HNRNPA1	IPI	UniProtKB:P62995	Human	PMID:10749975
Molecular Function	GO:0003723	RNA binding	HNRNPA1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	HNRNPA1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Hnrnpa1	IDA		Rat	PMID:23159318|RGD:10040996
Molecular Function	GO:0033592	RNA strand annealing activity	Hnrnpa1	IDA		Rat	PMID:1703006|RGD:10045979
Molecular Function	GO:1990825	sequence-specific mRNA binding	Hnrnpa1	IDA		Rat	PMID:11886857|RGD:625404
Molecular Function	GO:0003697	single-stranded DNA binding	HNRNPA1	IDA		Human	PMID:8521471
Molecular Function	GO:0003727	single-stranded RNA binding	Hnrnpa1	IDA		Rat	PMID:7727389|RGD:10045982
Molecular Function	GO:0061752	telomeric repeat-containing RNA binding	HNRNPA1	IDA		Human	PMID:23935072
Molecular Function	GO:0061752	telomeric repeat-containing RNA binding	HNRNPA1	IDA		Human	PMID:24529708
Cellular Component	GO:0071013	catalytic step 2 spliceosome	HNRNPA1	IDA		Human	PMID:11991638
Cellular Component	GO:0005737	cytoplasm	HNRNPA1	IDA		Human	PMID:8521471
Cellular Component	GO:0005829	cytosol	Hnrnpa1	IDA		Rat	PMID:23106379|RGD:10045574
Cellular Component	GO:0070062	extracellular exosome	HNRNPA1	HDA		Human	PMID:20458337
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	HNRNPA1	IDA		Human	PMID:33982369
Cellular Component	GO:0016020	membrane	HNRNPA1	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	HNRNPA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HNRNPA1	IDA		Human	PMID:21984414
Cellular Component	GO:0005654	nucleoplasm	HNRNPA1	IDA		Human	PMID:8521471
Cellular Component	GO:1990826	nucleoplasmic periphery of the nuclear pore complex	Hnrnpa1	IDA		Rat	PMID:10633080|RGD:10045985
Cellular Component	GO:0005634	nucleus	HNRNPA1	IDA		Human	PMID:23935072
Cellular Component	GO:0005634	nucleus	HNRNPA1	IDA		Human	PMID:27694260
Cellular Component	GO:0005634	nucleus	Hnrnpa1	IDA		Mouse	PMID:15615787
Cellular Component	GO:0005634	nucleus	Hnrnpa1	IDA		Rat	PMID:7503735|RGD:10040980
Cellular Component	GO:0032991	protein-containing complex	hnrnpa1b	IPI	ZFIN:ZDB-GENE-051113-276	Zfish	PMID:28076796
Cellular Component	GO:1990904	ribonucleoprotein complex	HNRNPA1	IDA		Human	PMID:17289661
Cellular Component	GO:1990904	ribonucleoprotein complex	HNRNPA1	IDA		Human	PMID:18809582
Cellular Component	GO:1990904	ribonucleoprotein complex	HNRNPA1	IDA		Human	PMID:23935072
Cellular Component	GO:0005681	spliceosomal complex	HNRNPA1	IDA		Human	PMID:25689357
Cellular Component	GO:0005681	spliceosomal complex	HNRNPA1	IDA		Human	PMID:9731529
Cellular Component	GO:0045202	synapse	Hnrnpa1	EXP		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Hnrnpa1	IDA		Mouse	PMID:25211037
Biological Process	GO:0000380	alternative mRNA splicing, via spliceosome	Hnrnpa1	IDA		Mouse	PMID:15798186
Biological Process	GO:1990000	amyloid fibril formation	HNRNPA1	IDA		Human	PMID:33311513
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Hnrnpa1	IEP		Rat	PMID:3062579|RGD:10041005
Biological Process	GO:0042149	cellular response to glucose starvation	HNRNPA1	IMP		Human	PMID:25689357
Biological Process	GO:0071310	cellular response to organic substance	Hnrnpa1	IMP		Rat	PMID:23106379|RGD:10045574
Biological Process	GO:0035865	cellular response to potassium ion	Hnrnpa1	IDA		Rat	PMID:17298175|RGD:10045993
Biological Process	GO:1903936	cellular response to sodium arsenite	HNRNPA1	IDA		Human	PMID:27694260
Biological Process	GO:0051170	import into nucleus	HNRNPA1	IDA		Human	PMID:8521471
Biological Process	GO:0051179	localization	HNRNPA1	EXP		Human	PMID:16901787
Biological Process	GO:0030324	lung development	Hnrnpa1	IEP		Rat	PMID:9457472|RGD:10045983
Biological Process	GO:0008584	male gonad development	Hnrnpa1	IEP		Rat	PMID:10978504|RGD:9685421
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	HNRNPA1	IMP		Human	PMID:23935072
Biological Process	GO:0051168	nuclear export	HNRNPA1	IDA		Human	PMID:8521471
Biological Process	GO:0045760	positive regulation of action potential	Hnrnpa1	IMP		Rat	PMID:15197740|RGD:10045966
Biological Process	GO:0010628	positive regulation of gene expression	Hnrnpa1	IMP		Rat	PMID:23106379|RGD:10045574
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	HNRNPA1	IDA		Human	PMID:23935072
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	HNRNPA1	IMP		Human	PMID:25689357
Biological Process	GO:0043484	regulation of RNA splicing	HNRNPA1	IDA		Human	PMID:28985503
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Hnrnpa1	IEP		Rat	PMID:23106379|RGD:10045574
Biological Process	GO:0008380	RNA splicing	Hnrnpa1	IDA		Mouse	PMID:15798186

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern