Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HNRNPL
  • Mouse genes Hnrnpl
  • Rat genes Fblim1,Hnrnpl
  • Zfish genes hnrnpl,hnrnpl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hnrnpl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Hnrnpl	IDA		Rat	PMID:15798208|RGD:9854643
Molecular Function	GO:1990715	mRNA CDS binding	Hnrnpl	IDA		Rat	PMID:16980303|RGD:10058976
Molecular Function	GO:0097157	pre-mRNA intronic binding	HNRNPL	IDA		Human	PMID:25623890
Molecular Function	GO:0005515	protein binding	HNRNPL	IPI	UniProtKB:P27695	Human	PMID:11809897
Molecular Function	GO:0005515	protein binding	HNRNPL	IPI	UniProtKB:Q8WVV9	Human	PMID:18669861
Molecular Function	GO:0005515	protein binding	HNRNPL	IPI	UniProtKB:P22626	Human	PMID:23976881
Molecular Function	GO:0005515	protein binding	HNRNPL	IPI	UniProtKB:P40337	Human	PMID:23976881
Molecular Function	GO:0005515	protein binding	HNRNPL	IPI	UniProtKB:P61978	Human	PMID:33174841
Molecular Function	GO:0005515	protein binding	HNRNPL	IPI	UniProtKB:Q17R98	Human	PMID:33174841
Molecular Function	GO:0005515	protein binding	Hnrnpl	IPI	PR:Q61990	Mouse	PMID:8871564
Molecular Function	GO:0005515	protein binding	Hnrnpl	IPI	RGD:1308649	Rat	PMID:18161049|RGD:9999434
Molecular Function	GO:0003723	RNA binding	HNRNPL	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	HNRNPL	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Hnrnpl	IDA		Mouse	PMID:27315481
Molecular Function	GO:0000976	transcription cis-regulatory region binding	HNRNPL	IDA		Human	PMID:11809897
Cellular Component	GO:0000785	chromatin	HNRNPL	IDA		Human	PMID:33174841
Cellular Component	GO:0005737	cytoplasm	HNRNPL	IDA		Human	PMID:33174841
Cellular Component	GO:0005737	cytoplasm	Hnrnpl	IDA		Rat	PMID:15798208|RGD:9854643
Cellular Component	GO:0005829	cytosol	Hnrnpl	IDA		Rat	PMID:10441480|RGD:9999432
Cellular Component	GO:0070062	extracellular exosome	HNRNPL	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	HNRNPL	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	HNRNPL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HNRNPL	IDA		Human	PMID:2687284
Cellular Component	GO:0005634	nucleus	HNRNPL	IDA		Human	PMID:15798186
Cellular Component	GO:0005634	nucleus	HNRNPL	IDA		Human	PMID:33174841
Cellular Component	GO:0005634	nucleus	Hnrnpl	IDA		Rat	PMID:19273590|RGD:9999430
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Hnrnpl	IDA		Rat	PMID:18161049|RGD:9999434
Cellular Component	GO:0045120	pronucleus	Hnrnpl	IDA		Mouse	PMID:7768196
Cellular Component	GO:1990904	ribonucleoprotein complex	HNRNPL	IDA		Human	PMID:17289661
Cellular Component	GO:1990904	ribonucleoprotein complex	HNRNPL	IDA		Human	PMID:2687284
Cellular Component	GO:1990904	ribonucleoprotein complex	HNRNPL	IDA		Human	PMID:33174841
Cellular Component	GO:0035770	ribonucleoprotein granule	HNRNPL	IDA		Human	PMID:17289661
Cellular Component	GO:0045202	synapse	Hnrnpl	EXP		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Hnrnpl	IDA		Mouse	PMID:25211037
Biological Process	GO:0034198	cellular response to amino acid starvation	Hnrnpl	IDA		Rat	PMID:19273590|RGD:9999430
Biological Process	GO:0007623	circadian rhythm	Hnrnpl	IEP		Rat	PMID:15798208|RGD:9854643
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HNRNPL	IMP		Human	PMID:33174841
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	Hnrnpl	IMP		Rat	PMID:22570490|RGD:9999428
Biological Process	GO:1902416	positive regulation of mRNA binding	Hnrnpl	IMP		Rat	PMID:19273590|RGD:9999430
Biological Process	GO:0045727	positive regulation of translation	Hnrnpl	IMP		Rat	PMID:19273590|RGD:9999430
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	HNRNPL	IMP		Human	PMID:25623890
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Hnrnpl	IMP		Mouse	MGI:MGI:5441689|PMID:22523384
Biological Process	GO:0048742	regulation of skeletal muscle fiber development	hnrnpl2	IMP	ZFIN:ZDB-MRPHLNO-220315-1	Zfish	PMID:33651408
Biological Process	GO:0048742	regulation of skeletal muscle fiber development	hnrnpl2	IMP	ZFIN:ZDB-MRPHLNO-220315-2	Zfish	PMID:33651408
Biological Process	GO:1901652	response to peptide	Hnrnpl	IEP		Rat	PMID:12576095|RGD:632932

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern