Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOMER2
  • Mouse genes Homer2
  • Rat genes Homer2
  • Zfish genes homer2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Homer2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Homer2	IDA		Mouse	PMID:10493740
Molecular Function	GO:0035256	G protein-coupled glutamate receptor binding	Homer2	IPI	UniProtKB:P31424	Rat	PMID:15758184|RGD:8554618
Molecular Function	GO:0035254	glutamate receptor binding	Homer2	IPI	RGD:2742|RGD:2746	Rat	PMID:9727012|RGD:632975
Molecular Function	GO:0042802	identical protein binding	Homer2	IPI	RGD:620705	Rat	PMID:9727012|RGD:632975
Molecular Function	GO:0005515	protein binding	HOMER2	IPI	UniProtKB:O95644|UniProtKB:Q13469|UniProtKB:Q14934	Human	PMID:18218901
Molecular Function	GO:0005515	protein binding	HOMER2	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOMER2	IPI	UniProtKB:Q9H4P4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Homer2	IPI	PR:P97772	Mouse	PMID:9808458
Molecular Function	GO:0005515	protein binding	Homer2	IPI	PR:P97772	Mouse	PMID:10493740
Molecular Function	GO:0005515	protein binding	Homer2	IPI	RGD:1309471	Rat	PMID:15944415|RGD:2302220
Molecular Function	GO:0005515	protein binding	Homer2	IPI	UniProtKB:Q6WQJ1	Rat	PMID:17584991|RGD:25671399
Molecular Function	GO:0019904	protein domain specific binding	Homer2	IMP		Rat	PMID:15944415|RGD:2302220
Molecular Function	GO:0044877	protein-containing complex binding	Homer2	IPI	RGD:628725	Rat	PMID:9727012|RGD:632975
Molecular Function	GO:0030160	synaptic receptor adaptor activity	Homer2	IDA		Mouse	PMID:10493740
Cellular Component	GO:0045177	apical part of cell	Homer2	IDA		Mouse	PMID:12860966
Cellular Component	GO:0005737	cytoplasm	HOMER2	IDA		Human	PMID:25816005
Cellular Component	GO:0005737	cytoplasm	Homer2	IMP	MGI:MGI:3526530	Mouse	PMID:10493740
Cellular Component	GO:0005829	cytosol	HOMER2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Homer2	IDA		Rat	PMID:15944415|RGD:2302220
Cellular Component	GO:0098978	glutamatergic synapse	Homer2	IDA		Mouse	PMID:24530450
Cellular Component	GO:0043229	intracellular organelle	Homer2	IDA		Rat	PMID:17584991|RGD:25671399
Cellular Component	GO:0043025	neuronal cell body	Homer2	IDA		Rat	PMID:15944415|RGD:2302220
Cellular Component	GO:0005886	plasma membrane	Homer2	IDA		Rat	PMID:17584991|RGD:25671399
Cellular Component	GO:0014069	postsynaptic density	Homer2	IDA		Mouse	PMID:24530450
Cellular Component	GO:0032426	stereocilium tip	Homer2	IDA		Mouse	MGI:MGI:5688813|PMID:25816005
Biological Process	GO:0048148	behavioral response to cocaine	Homer2	IMP	MGI:MGI:3526530	Mouse	PMID:15294147
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	Homer2	IMP	MGI:MGI:3526530	Mouse	PMID:12860966
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	HOMER2	IMP		Human	PMID:18218901
Biological Process	GO:0032703	negative regulation of interleukin-2 production	HOMER2	IMP		Human	PMID:18218901
Biological Process	GO:0021628	olfactory nerve formation	homer2	IMP	ZFIN:ZDB-MRPHLNO-140417-4	Zfish	PMID:24427155
Biological Process	GO:0071699	olfactory placode morphogenesis	homer2	IMP	ZFIN:ZDB-MRPHLNO-140417-4	Zfish	PMID:24427155
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Homer2	IDA		Mouse	PMID:12860966
Biological Process	GO:0007605	sensory perception of sound	HOMER2	IMP		Human	PMID:25816005
Biological Process	GO:0007605	sensory perception of sound	Homer2	IMP		Mouse	MGI:MGI:5688813|PMID:25816005

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern