Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOOK1
  • Mouse genes Hook1
  • Rat genes Hook1
  • Zfish genes hook1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hook1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Hook1	IDA		Mouse	PMID:14668490
Molecular Function	GO:0042802	identical protein binding	HOOK1	IPI	UniProtKB:Q9UJC3	Human	PMID:18799622
Molecular Function	GO:0042802	identical protein binding	HOOK1	IPI	UniProtKB:Q9UJC3	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	HOOK1	IPI	UniProtKB:Q9UJC3	Human	PMID:32296183
Molecular Function	GO:0008017	microtubule binding	Hook1	IDA		Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P51149|UniProtKB:P51151|UniProtKB:P62491	Human	PMID:15471887
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q13286	Human	PMID:15471887
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q99459	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q86VS8	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q96ED9	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9H8T0	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:A8K8V0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:O75604	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P11802	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P25791	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q8N0S2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9H8T0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9P0N9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P11802	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q86VS8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P35613	Human	PMID:29423001
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q99459	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P11802	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9P0N9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9UBB9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:O00189|UniProtKB:Q86VS8|UniProtKB:Q8N612|UniProtKB:Q96ED9|UniProtKB:Q9H8T0	Human	PMID:32073997
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P11802	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P13682	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P25791-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P51504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q2TBE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q3B820	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q5TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q7Z3I7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q86SG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q86VS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q96H86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q99459	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9H8T0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9P0N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9UBB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q9UFB7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:O75376	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOOK1	IPI	UniProtKB:Q00535	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hook1	IPI	UniProtKB:Q80ZU5	Mouse	MGI:MGI:5897495|PMID:28283191
Molecular Function	GO:0005515	protein binding	Hook1	IPI	UniProtKB:P18572	Mouse	MGI:MGI:6356214|PMID:29423001
Molecular Function	GO:0005515	protein binding	Hook1	IPI	UniProtKB:Q3V0F0	Mouse	MGI:MGI:3830438|PMID:19091768
Molecular Function	GO:0005515	protein binding	Hook1	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Hook1	IPI	PR:G5E8K5	Mouse	PMID:15823567
Molecular Function	GO:0005515	protein binding	Hook1	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0005515	protein binding	Hook1	IPI	UniProtKB:B5DFJ4	Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0042803	protein homodimerization activity	HOOK1	IDA		Human	PMID:32073997
Cellular Component	GO:0005737	cytoplasm	HOOK1	IDA		Human	PMID:15471887
Cellular Component	GO:0070695	FHF complex	HOOK1	IDA		Human	PMID:18799622
Cellular Component	GO:0070695	FHF complex	HOOK1	IDA		Human	PMID:32073997
Cellular Component	GO:0015630	microtubule cytoskeleton	Hook1	IDA		Mouse	PMID:12075009
Biological Process	GO:0031122	cytoplasmic microtubule organization	Hook1	IMP	MGI:MGI:1856652	Mouse	PMID:16540102
Biological Process	GO:0045022	early endosome to late endosome transport	HOOK1	IMP		Human	PMID:18799622
Biological Process	GO:0007032	endosome organization	HOOK1	IMP		Human	PMID:18799622
Biological Process	GO:0008333	endosome to lysosome transport	HOOK1	IMP		Human	PMID:18799622
Biological Process	GO:0007030	Golgi organization	Hook1	IMP	MGI:MGI:1856652	Mouse	PMID:16540102
Biological Process	GO:0007040	lysosome organization	HOOK1	IMP		Human	PMID:18799622
Biological Process	GO:1905198	manchette assembly	Hook1	IMP	MGI:MGI:1856652	Mouse	PMID:9674995
Biological Process	GO:1905198	manchette assembly	Hook1	IMP	MGI:MGI:1856652	Mouse	PMID:16540102
Biological Process	GO:1905719	protein localization to perinuclear region of cytoplasm	HOOK1	IMP		Human	PMID:32073997
Biological Process	GO:0007286	spermatid development	Hook1	IMP	MGI:MGI:1856652	Mouse	PMID:12075009

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern