Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOOK2
  • Mouse genes Hook2
  • Rat genes Hook2
  • Zfish genes hook2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hook2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	HOOK2	IPI	UniProtKB:Q96ED9	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q15311	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q8N5R6	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9H8T0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q7Z7A1	Human	PMID:17140400
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q86VS8	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9H8T0	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9UJC3	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q6PJT7	Human	PMID:19273536
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:O43463	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q7Z3B3	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9H8T0	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:O43463	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q08E77	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q2TBE0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q53FD0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q7Z3B3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q96IX9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9BXS5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9UII6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9H8T0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q15311	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9UJC3	Human	PMID:32073997
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q5W0V3	Human	PMID:34882091
Molecular Function	GO:0005515	protein binding	HOOK2	IPI	UniProtKB:Q9H8T0	Human	PMID:34882091
Molecular Function	GO:0005515	protein binding	Hook2	IPI	UniProtKB:Q9D5S7	Mouse	MGI:MGI:5645720|PMID:25781171
Cellular Component	GO:0005813	centrosome	HOOK2	IDA		Human	PMID:17140400
Cellular Component	GO:0005813	centrosome	hook2	IDA		Zfish	PMID:30674580
Cellular Component	GO:0005829	cytosol	HOOK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070695	FHF complex	HOOK2	IDA		Human	PMID:18799622
Cellular Component	GO:0070695	FHF complex	HOOK2	IDA		Human	PMID:32073997
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	HOOK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005802	trans-Golgi network	HOOK2	IDA		Human	PMID:32073997
Biological Process	GO:0045022	early endosome to late endosome transport	HOOK2	IMP		Human	PMID:18799622
Biological Process	GO:0007032	endosome organization	HOOK2	IMP		Human	PMID:18799622
Biological Process	GO:0008333	endosome to lysosome transport	HOOK2	IMP		Human	PMID:18799622
Biological Process	GO:0007040	lysosome organization	HOOK2	IMP		Human	PMID:18799622
Biological Process	GO:1905719	protein localization to perinuclear region of cytoplasm	HOOK2	IMP		Human	PMID:32073997

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern