Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOOK3
  • Mouse genes Hook3
  • Rat genes Hook3
  • Zfish genes hook3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hook3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034452	dynactin binding	HOOK3	IDA		Human	PMID:27482052
Molecular Function	GO:0045505	dynein intermediate chain binding	HOOK3	IDA		Human	PMID:27482052
Molecular Function	GO:0045503	dynein light chain binding	HOOK3	IPI	UniProtKB:Q9Y6G9	Human	PMID:27482052
Molecular Function	GO:0042802	identical protein binding	HOOK3	IPI	UniProtKB:Q86VS8	Human	PMID:18799622
Molecular Function	GO:0008017	microtubule binding	HOOK3	IDA		Human	PMID:11238449
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:P21757	Human	PMID:17237231
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q96ED9	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q9H8T0	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q9UJC3	Human	PMID:18799622
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q9UJC3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q9UJC3	Human	PMID:32073997
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:O43310-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:P13646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q96PV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOOK3	IPI	UniProtKB:Q9UJC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hook3	IPI	PR:Q9R0L6	Mouse	PMID:20152126
Molecular Function	GO:0005515	protein binding	Hook3	IPI	UniProtKB:P21757	Rat	PMID:17237231|RGD:8553823
Cellular Component	GO:0034451	centriolar satellite	Hook3	IDA		Mouse	PMID:20152126
Cellular Component	GO:0005813	centrosome	Hook3	IDA		Mouse	PMID:20152126
Cellular Component	GO:0005801	cis-Golgi network	HOOK3	IDA		Human	PMID:11238449
Cellular Component	GO:0005737	cytoplasm	Hook3	IDA		Mouse	PMID:20152126
Cellular Component	GO:0070695	FHF complex	HOOK3	IDA		Human	PMID:18799622
Cellular Component	GO:0070695	FHF complex	HOOK3	IDA		Human	PMID:32073997
Cellular Component	GO:0000242	pericentriolar material	Hook3	IDA		Mouse	MGI:MGI:4457463|PMID:20152126
Biological Process	GO:0031122	cytoplasmic microtubule organization	HOOK3	IMP		Human	PMID:11238449
Biological Process	GO:0045022	early endosome to late endosome transport	HOOK3	IMP		Human	PMID:18799622
Biological Process	GO:0007032	endosome organization	HOOK3	IMP		Human	PMID:18799622
Biological Process	GO:0008333	endosome to lysosome transport	HOOK3	IMP		Human	PMID:18799622
Biological Process	GO:0051645	Golgi localization	HOOK3	IMP		Human	PMID:11238449
Biological Process	GO:0022027	interkinetic nuclear migration	Hook3	IMP		Mouse	PMID:20152126
Biological Process	GO:0007040	lysosome organization	HOOK3	IMP		Human	PMID:18799622
Biological Process	GO:0034454	microtubule anchoring at centrosome	Hook3	IMP		Mouse	PMID:20152126
Biological Process	GO:0050768	negative regulation of neurogenesis	Hook3	IMP		Mouse	MGI:MGI:4457463|PMID:20152126
Biological Process	GO:0097150	neuronal stem cell population maintenance	Hook3	IMP		Mouse	PMID:20152126
Biological Process	GO:0071539	protein localization to centrosome	Hook3	IMP		Mouse	PMID:20152126
Biological Process	GO:1905719	protein localization to perinuclear region of cytoplasm	HOOK3	IMP		Human	PMID:32073997

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern