Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA10
  • Mouse genes Hoxa10
  • Rat genes Hoxa10,LOC100911668
  • Zfish genes hoxa10b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXA10	IDA		Human	PMID:21471217
Molecular Function	GO:0042826	histone deacetylase binding	HOXA10	IPI	UniProtKB:Q8IXJ6	Human	PMID:15213244
Molecular Function	GO:0005515	protein binding	HOXA10	IPI	UniProtKB:P17947	Human	PMID:18692240
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXA10	IDA		Human	PMID:21471217
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXA10	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	HOXA10	IDA		Human	PMID:15213244
Cellular Component	GO:0005654	nucleoplasm	HOXA10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HOXA10	IDA		Human	PMID:15213244
Cellular Component	GO:0005667	transcription regulator complex	Hoxa10	IDA		Mouse	PMID:9343407
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxa10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxa10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0008584	male gonad development	Hoxa10	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0008584	male gonad development	Hoxa10	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0007275	multicellular organism development	Hoxa10	IDA		Mouse	PMID:11900456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXA10	IDA		Human	PMID:21471217
Biological Process	GO:0030850	prostate gland development	Hoxa10	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxa10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxa10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0010468	regulation of gene expression	Hoxa10	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0010468	regulation of gene expression	Hoxa10	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0043627	response to estrogen	Hoxa10	IEP		Rat	PMID:18653720|RGD:11353969
Biological Process	GO:0033574	response to testosterone	Hoxa10	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0007338	single fertilization	Hoxa10	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0007338	single fertilization	Hoxa10	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0001501	skeletal system development	Hoxa10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxa10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0007283	spermatogenesis	Hoxa10	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0007283	spermatogenesis	Hoxa10	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa10	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa10	IGI	MGI:MGI:96171	Mouse	PMID:23760953

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern