Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA11
  • Mouse genes Hoxa11
  • Rat genes Hoxa11
  • Zfish genes hoxa11a,hoxa11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Hoxa11	IPI	UniProtKB:Q62232	Mouse	MGI:MGI:5442222|PMID:22902740
Molecular Function	GO:0005515	protein binding	Hoxa11	IPI	UniProtKB:O88513	Mouse	MGI:MGI:3038045|PMID:14973489
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXA11	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	HOXA11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Hoxa11	IDA		Mouse	MGI:MGI:3768605|PMID:17785448
Cellular Component	GO:0032993	protein-DNA complex	Hoxa11	IDA		Mouse	MGI:MGI:3768605|PMID:17785448
Cellular Component	GO:0005667	transcription regulator complex	Hoxa11	IDA		Mouse	PMID:9343407
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:12869760
Biological Process	GO:0060348	bone development	Hoxa11	IMP	MGI:MGI:2135973	Mouse	PMID:7789268
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:11493536
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0048468	cell development	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0002063	chondrocyte development	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0002062	chondrocyte differentiation	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0048589	developmental growth	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0009953	dorsal/ventral pattern formation	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:11493536
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:12869760
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:22916278
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:20978074
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:20978074
Biological Process	GO:0008584	male gonad development	Hoxa11	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0008584	male gonad development	Hoxa11	IMP	MGI:MGI:2135973	Mouse	PMID:7789268
Biological Process	GO:0008584	male gonad development	Hoxa11	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0007501	mesodermal cell fate specification	Hoxa11	IDA		Mouse	MGI:MGI:3768605|PMID:17785448
Biological Process	GO:0001656	metanephros development	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:12050119
Biological Process	GO:0001656	metanephros development	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:12050119
Biological Process	GO:0007275	multicellular organism development	Hoxa11	IDA		Mouse	PMID:11900456
Biological Process	GO:0001759	organ induction	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:12050119
Biological Process	GO:0001759	organ induction	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:12050119
Biological Process	GO:1902761	positive regulation of chondrocyte development	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:14668414
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Hoxa11	IDA		Mouse	MGI:MGI:3768605|PMID:17785448
Biological Process	GO:0030850	prostate gland development	Hoxa11	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:12869760
Biological Process	GO:0032330	regulation of chondrocyte differentiation	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:22916278
Biological Process	GO:0010468	regulation of gene expression	Hoxa11	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0010468	regulation of gene expression	Hoxa11	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0043627	response to estrogen	Hoxa11	IEP		Rat	PMID:18653720|RGD:11353969
Biological Process	GO:0033574	response to testosterone	Hoxa11	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0007338	single fertilization	Hoxa11	IMP	MGI:MGI:2135973	Mouse	PMID:7789268
Biological Process	GO:0007338	single fertilization	Hoxa11	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0007338	single fertilization	Hoxa11	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0001501	skeletal system development	Hoxa11	IGI	MGI:MGI:96193	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxa11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxa11	IMP	MGI:MGI:1934269	Mouse	PMID:7596412
Biological Process	GO:0007283	spermatogenesis	Hoxa11	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0007283	spermatogenesis	Hoxa11	IMP	MGI:MGI:2135973	Mouse	PMID:7789268
Biological Process	GO:0007283	spermatogenesis	Hoxa11	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa11	IGI	MGI:MGI:96180	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa11	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa11	IMP	MGI:MGI:2135973	Mouse	PMID:7789268

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern