Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA13
  • Mouse genes Hoxa13
  • Rat genes Hoxa13
  • Zfish genes hoxa13a,hoxa13b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Hoxa13	IDA		Mouse	PMID:27706137
Molecular Function	GO:0003677	DNA binding	Hoxa13	IDA		Mouse	PMID:19168674
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hoxa13	IDA		Mouse	PMID:27706137
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxa13	IDA		Mouse	PMID:16314414
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	hoxa13b	IDA		Zfish	PMID:19222565
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	hoxa13a	IDA		Zfish	PMID:19222565
Molecular Function	GO:0005515	protein binding	Hoxa13	IPI	UniProtKB:P97454	Mouse	MGI:MGI:3589511|PMID:16087734
Molecular Function	GO:0005515	protein binding	Hoxa13	IPI	PR:Q60954-2	Mouse	PMID:15617687
Molecular Function	GO:0005515	protein binding	Hoxa13	IPI	PR:Q60954-1	Mouse	PMID:15617687
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hoxa13	IMP		Mouse	MGI:MGI:5572825|PMID:15342482
Molecular Function	GO:0043565	sequence-specific DNA binding	HOXA13	IDA		Human	PMID:23332764
Molecular Function	GO:0043565	sequence-specific DNA binding	HOXA13	IMP		Human	PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXA13	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Hoxa13	IDA		Mouse	PMID:18483557
Cellular Component	GO:0005694	chromosome	HOXA13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045111	intermediate filament cytoskeleton	HOXA13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXA13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hoxa13	IDA		Mouse	PMID:15733672
Cellular Component	GO:0005634	nucleus	Hoxa13	IDA		Mouse	PMID:15617687
Biological Process	GO:0009653	anatomical structure morphogenesis	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0009887	animal organ morphogenesis	Hoxa13	IMP	MGI:MGI:1857336	Mouse	PMID:10210434
Biological Process	GO:0048844	artery morphogenesis	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0060442	branching involved in prostate gland morphogenesis	Hoxa13	IMP	MGI:MGI:1857336	Mouse	PMID:10210434
Biological Process	GO:0006351	DNA-templated transcription	hoxa13b	IDA		Zfish	PMID:19222565|ZFIN:ZDB-PUB-090227-5
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Hoxa13	IMP	MGI:MGI:2150506	Mouse	PMID:15733672
Biological Process	GO:0048619	embryonic hindgut morphogenesis	Hoxa13	IMP		Rat	PMID:17161201|RGD:1599527
Biological Process	GO:0060847	endothelial cell fate specification	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0001886	endothelial cell morphogenesis	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0033333	fin development	hoxa13b	IMP	ZFIN:ZDB-GENO-191231-13	Zfish	PMID:27533041
Biological Process	GO:0033333	fin development	hoxa13b	IGI	ZFIN:ZDB-GENE-990415-5	Zfish	PMID:27533041
Biological Process	GO:0033333	fin development	hoxa13b	IGI	ZFIN:ZDB-GENE-980526-365,ZFIN:ZDB-GENE-990415-119	Zfish	PMID:27533041
Biological Process	GO:0033333	fin development	hoxa13a	IGI	ZFIN:ZDB-GENE-980526-365	Zfish	PMID:27533041
Biological Process	GO:0033333	fin development	hoxa13a	IGI	ZFIN:ZDB-GENE-980526-365,ZFIN:ZDB-GENE-990415-119	Zfish	PMID:27533041
Biological Process	GO:0033333	fin development	hoxa13a	IMP	ZFIN:ZDB-GENO-191231-12	Zfish	PMID:27533041
Biological Process	GO:0048839	inner ear development	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0030539	male genitalia development	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0097152	mesenchymal cell apoptotic process	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0140014	mitotic nuclear division	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	hoxa13b	IDA		Zfish	PMID:19222565
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	hoxa13a	IDA		Zfish	PMID:19222565
Biological Process	GO:2001055	positive regulation of mesenchymal cell apoptotic process	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa13	IDA		Mouse	MGI:MGI:5902679|PMID:21829694
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa13	IDA		Mouse	PMID:16314414
Biological Process	GO:0030850	prostate gland development	Hoxa13	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0030510	regulation of BMP signaling pathway	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:12783783
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	hoxa13b	IDA		Zfish	PMID:19222565|ZFIN:ZDB-PUB-090227-5
Biological Process	GO:0033574	response to testosterone	Hoxa13	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0001894	tissue homeostasis	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0006366	transcription by RNA polymerase II	Hoxa13	IDA		Mouse	PMID:16314414
Biological Process	GO:0001570	vasculogenesis	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557
Biological Process	GO:0003281	ventricular septum development	Hoxa13	IMP	MGI:MGI:2152356	Mouse	PMID:18483557

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern