Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA5
  • Mouse genes Hoxa5
  • Rat genes Hoxa5
  • Zfish genes hoxa5a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	HOXA5	IDA		Human	PMID:8657138
Molecular Function	GO:0003677	DNA binding	Hoxa5	IDA		Mouse	PMID:7911971
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXA5	IDA		Human	PMID:10879542
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HOXA5	IDA		Human	PMID:10879542
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HOXA5	IDA		Human	PMID:16756717
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:Q15672	Human	PMID:15545268
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:P40425	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXA5	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hoxa5	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529|PMID:20599664
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXA5	IDA		Human	PMID:10879542
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXA5	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	HOXA5	IDA		Human	PMID:15545268
Cellular Component	GO:0005634	nucleus	Hoxa5	IDA		Mouse	PMID:8635464
Cellular Component	GO:0005634	nucleus	Hoxa5	IDA		Mouse	PMID:2890554
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa5	IGI	MGI:MGI:96196	Mouse	PMID:17626057
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa5	IMP	MGI:MGI:3723623	Mouse	PMID:17417799
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:7901120
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9603431
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa5	IGI	MGI:MGI:96186	Mouse	PMID:17626057
Biological Process	GO:0060435	bronchiole development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0060536	cartilage morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0016477	cell migration	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:17003488
Biological Process	GO:0060764	cell-cell signaling involved in mammary gland development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:16607641
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa5	IGI	MGI:MGI:96196	Mouse	PMID:17626057
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa5	IGI	MGI:MGI:96186	Mouse	PMID:17626057
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxa5	IMP	MGI:MGI:3723623	Mouse	PMID:17417799
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9603431
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:7901120
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0060574	intestinal epithelial cell maturation	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:10564089
Biological Process	GO:0060481	lobar bronchus epithelium development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0048286	lung alveolus development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:15295088
Biological Process	GO:0048286	lung alveolus development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:17003488
Biological Process	GO:0030324	lung development	Hoxa5	IMP	MGI:MGI:3723623	Mouse	PMID:17417799
Biological Process	GO:0060480	lung goblet cell differentiation	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:17003488
Biological Process	GO:0060484	lung-associated mesenchyme development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0060749	mammary gland alveolus development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:16607641
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:16607641
Biological Process	GO:0060638	mesenchymal-epithelial cell signaling	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:16607641
Biological Process	GO:0002009	morphogenesis of an epithelium	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0035264	multicellular organism growth	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:12815622
Biological Process	GO:0016525	negative regulation of angiogenesis	HOXA5	IMP		Human	PMID:17957028
Biological Process	GO:0016525	negative regulation of angiogenesis	HOXA5	IMP		Human	PMID:23136161
Biological Process	GO:0045647	negative regulation of erythrocyte differentiation	HOXA5	IDA		Human	PMID:10397719
Biological Process	GO:0007389	pattern specification process	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:11900462
Biological Process	GO:0043065	positive regulation of apoptotic process	HOXA5	IDA		Human	PMID:10879542
Biological Process	GO:0010628	positive regulation of gene expression	HOXA5	IDA		Human	PMID:10875927
Biological Process	GO:0045639	positive regulation of myeloid cell differentiation	HOXA5	IDA		Human	PMID:10397719
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXA5	IDA		Human	PMID:10879542
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXA5	IDA		Human	PMID:16756717
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa5	IDA		Mouse	PMID:8635464
Biological Process	GO:0033599	regulation of mammary gland epithelial cell proliferation	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:16607641
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:15295088
Biological Process	GO:0003016	respiratory system process	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0001501	skeletal system development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:11900462
Biological Process	GO:0030878	thyroid gland development	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:12815622
Biological Process	GO:0060535	trachea cartilage morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0060439	trachea morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:9441679
Biological Process	GO:0060439	trachea morphogenesis	Hoxa5	IMP	MGI:MGI:2150397	Mouse	PMID:15295088

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern