Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA7
  • Mouse genes Hoxa7
  • Rat genes Hoxa7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Hoxa7	IDA		Mouse	PMID:8264592
Molecular Function	GO:0003677	DNA binding	Hoxa7	IDA		Mouse	PMID:7911971
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXA7	IDA		Human	PMID:11435435
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxa7	IDA		Mouse	PMID:7911971
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HOXA7	IPI	UniProtKB:P40425	Human	PMID:18973687
Molecular Function	GO:0005515	protein binding	HOXA7	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXA7	IDA		Human	PMID:11435435
Molecular Function	GO:0043565	sequence-specific DNA binding	HOXA7	IDA		Human	PMID:11435435
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXA7	IDA		Human	PMID:28473536
Cellular Component	GO:0031965	nuclear membrane	HOXA7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXA7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hoxa7	IDA		Mouse	PMID:8264592
Biological Process	GO:0001525	angiogenesis	HOXA7	IEP		Human	PMID:17972163
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa7	IGI	MGI:MGI:96188	Mouse	PMID:9784603
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxa7	IGI	MGI:MGI:96188	Mouse	PMID:9784603
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	HOXA7	IDA		Human	PMID:14704364
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HOXA7	IDA		Human	PMID:11435435
Biological Process	GO:0045617	negative regulation of keratinocyte differentiation	HOXA7	IDA		Human	PMID:11435435
Biological Process	GO:0002686	negative regulation of leukocyte migration	HOXA7	IDA		Human	PMID:14704364
Biological Process	GO:0045656	negative regulation of monocyte differentiation	HOXA7	IDA		Human	PMID:14704364
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HOXA7	IDA		Human	PMID:11435435
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HOXA7	IDA		Human	PMID:14704364
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hoxa7	IDA		Mouse	PMID:8649375
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXA7	IDA		Human	PMID:11435435
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa7	IDA		Mouse	PMID:8264592
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa7	IDA		Mouse	PMID:7911971
Biological Process	GO:0048863	stem cell differentiation	Hoxa7	IDA		Mouse	PMID:19796622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern