Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA9
  • Mouse genes Hoxa9
  • Rat genes Hoxa9
  • Zfish genes hoxa9a,hoxa9b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hoxa9	IDA		Mouse	MGI:MGI:3834546|PMID:17327400
Molecular Function	GO:0019899	enzyme binding	HOXA9	IPI	UniProtKB:O14744	Human	PMID:22269951
Molecular Function	GO:0005515	protein binding	HOXA9	IPI	UniProtKB:Q15654	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HOXA9	IPI	UniProtKB:Q15654	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	HOXA9	IPI	UniProtKB:O14744	Human	PMID:22269951
Molecular Function	GO:0005515	protein binding	HOXA9	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hoxa9	IPI	UniProtKB:Q9Z148	Mouse	MGI:MGI:5566549|PMID:24532712
Molecular Function	GO:0005515	protein binding	Hoxa9	IPI	UniProtKB:P41778	Mouse	MGI:MGI:5917381|PMID:22745600
Molecular Function	GO:0005515	protein binding	Hoxa9	IPI	UniProtKB:P41778	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Hoxa9	IPI	PR:Q60954	Mouse	PMID:9343407
Molecular Function	GO:0005515	protein binding	Hoxa9	IPI	PR:P45481	Mouse	PMID:15161102
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hoxa9	IMP		Mouse	MGI:MGI:5822990|PMID:10082572
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXA9	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	HOXA9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HOXA9	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005667	transcription regulator complex	Hoxa9	IDA		Mouse	PMID:9343407
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:17626057
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa9	IGI	MGI:MGI:96199	Mouse	PMID:17626057
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa9	IGI	MGI:MGI:96190	Mouse	PMID:17626057
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:8625797
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa9	IMP	MGI:MGI:2150411	Mouse	PMID:8625797
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa9	IGI	MGI:MGI:96190	Mouse	PMID:9013929
Biological Process	GO:0060216	definitive hemopoiesis	Hoxa9	IGI	MGI:MGI:96185	Mouse	PMID:17761289
Biological Process	GO:0060216	definitive hemopoiesis	Hoxa9	IGI	MGI:MGI:96184	Mouse	PMID:17761289
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:8625797
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa9	IGI	MGI:MGI:96199	Mouse	PMID:17626057
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa9	IGI	MGI:MGI:96190	Mouse	PMID:17626057
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:8625797
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:17626057
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa9	IMP	MGI:MGI:2150411	Mouse	PMID:8625797
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa9	IGI	MGI:MGI:96190	Mouse	PMID:9013929
Biological Process	GO:0042118	endothelial cell activation	HOXA9	IMP		Human	PMID:22269951
Biological Process	GO:0008584	male gonad development	Hoxa9	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0008584	male gonad development	Hoxa9	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0030879	mammary gland development	Hoxa9	IGI	MGI:MGI:96190	Mouse	PMID:9892669
Biological Process	GO:0030879	mammary gland development	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:9892669
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	Hoxa9	IDA		Mouse	MGI:MGI:5447628|PMID:11438208
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa9	IDA		Mouse	MGI:MGI:3834546|PMID:17327400
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxa9	IMP		Mouse	MGI:MGI:3834546|PMID:17327400
Biological Process	GO:0030850	prostate gland development	Hoxa9	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxa9	IGI	MGI:MGI:96210	Mouse	PMID:8625797
Biological Process	GO:0010468	regulation of gene expression	Hoxa9	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0010468	regulation of gene expression	Hoxa9	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0033574	response to testosterone	Hoxa9	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0007338	single fertilization	Hoxa9	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0007338	single fertilization	Hoxa9	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0007283	spermatogenesis	Hoxa9	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0007283	spermatogenesis	Hoxa9	IGI	MGI:MGI:96172	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa9	IGI	MGI:MGI:96171	Mouse	PMID:23760953
Biological Process	GO:0060065	uterus development	Hoxa9	IGI	MGI:MGI:96172	Mouse	PMID:23760953

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern