Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hoxb5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HOXB5
- Mouse genes Hoxb5
- Rat genes Hoxb5
- Zfish genes hoxb5a,hoxb5b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxb5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Hoxb5	IDA		Mouse	PMID:12897140
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hoxb5	IDA		Mouse	MGI:MGI:2670246\|PMID:12897140
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxb5	IDA		Mouse	PMID:12897140
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P43364-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P56545-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q13363-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:A2RRN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:A6NC98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:O95751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P40424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P40425	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P43364	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P54257	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P60371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:P67870	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q13137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q495M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q5T6S3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q5VU43-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q6NX45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q8IYF3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q8NI38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q92845	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q96ED9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q96RU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9BUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9BYD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9BYU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9GZV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9H0C1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9H707	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9HBT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9NQZ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9NWX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9NYA3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9Y2T1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXB5	IPI	UniProtKB:Q9Y4D7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hoxb5	IPI	UniProtKB:O35317	Mouse	MGI:MGI:4455093\|PMID:20211142
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hoxb5	IDA		Mouse	MGI:MGI:2670246\|PMID:12897140
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXB5	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	HOXB5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	HOXB5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXB5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hoxb5	IDA		Mouse	PMID:10579975
Cellular Component	GO:0005634	nucleus	Hoxb5	IDA		Mouse	PMID:1353982
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96177	Mouse	PMID:17626057
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96187	Mouse	PMID:7828847
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96188	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96183	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96190	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IMP	MGI:MGI:2151484	Mouse	PMID:7828847
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96196	Mouse	PMID:17626057
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96182	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96189	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96187	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96184	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb5	IGI	MGI:MGI:96185	Mouse	PMID:10885747
Biological Process	GO:0007420	brain development	hoxb5b	IMP		Zfish	PMID:11440248
Biological Process	GO:0007420	brain development	hoxb5a	IMP		Zfish	PMID:11440248
Biological Process	GO:0010002	cardioblast differentiation	hoxb5b	IMP	ZFIN:ZDB-MRPHLNO-090908-4	Zfish	PMID:19081079
Biological Process	GO:0001708	cell fate specification	hoxb5b	IMP		Zfish	PMID:11440248
Biological Process	GO:0001708	cell fate specification	hoxb5a	IMP		Zfish	PMID:11440248
Biological Process	GO:0048706	embryonic skeletal system development	Hoxb5	IGI	MGI:MGI:96177	Mouse	PMID:17626057
Biological Process	GO:0048706	embryonic skeletal system development	Hoxb5	IGI	MGI:MGI:96196	Mouse	PMID:17626057
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96189	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96184	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96190	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96183	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96182	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96185	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IMP		Mouse	PMID:7828847
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96187	Mouse	PMID:7828847
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96187	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb5	IGI	MGI:MGI:96188	Mouse	PMID:10885747
Biological Process	GO:0045446	endothelial cell differentiation	Hoxb5	IDA		Mouse	PMID:12897140
Biological Process	GO:0007507	heart development	hoxb5b	IGI	ZFIN:ZDB-MRPHLNO-090908-4,ZFIN:ZDB-MRPHLNO-131018-1	Zfish	PMID:23990796
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxb5	IDA		Mouse	MGI:MGI:2670246\|PMID:12897140
Biological Process	GO:0006355	regulation of DNA-templated transcription	Hoxb5	IDA		Mouse	PMID:12897140

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.