Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXC13
  • Mouse genes Hoxc13
  • Rat genes Hoxc13
  • Zfish genes hoxc13a,hoxc13b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxc13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Hoxc13	IDA		Mouse	PMID:21191399
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hoxc13	IDA		Mouse	PMID:21191399
Molecular Function	GO:0003700	DNA-binding transcription factor activity	HOXC13	IDA		Human	PMID:27506447
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HOXC13	IPI	UniProtKB:P17947	Human	PMID:27506447
Molecular Function	GO:0005515	protein binding	HOXC13	IPI	UniProtKB:P32519	Human	PMID:18692240
Molecular Function	GO:0005515	protein binding	HOXC13	IPI	UniProtKB:O95644	Human	PMID:25609649
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXC13	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	HOXC13	IMP		Human	PMID:27506447
Cellular Component	GO:0005634	nucleus	Hoxc13	IDA		Mouse	PMID:21191399
Biological Process	GO:0009653	anatomical structure morphogenesis	Hoxc13	IMP	MGI:MGI:1926422	Mouse	PMID:9420327
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc13	IMP	MGI:MGI:1926422	Mouse	PMID:9420327
Biological Process	GO:0031101	fin regeneration	hoxc13a	IMP	ZFIN:ZDB-MRPHLNO-041208-3	Zfish	PMID:17437127
Biological Process	GO:0031101	fin regeneration	hoxc13a	IMP	ZFIN:ZDB-MRPHLNO-070730-3	Zfish	PMID:17437127
Biological Process	GO:0031101	fin regeneration	hoxc13b	IMP	ZFIN:ZDB-MRPHLNO-041208-2	Zfish	PMID:17437127
Biological Process	GO:0031101	fin regeneration	hoxc13b	IMP	ZFIN:ZDB-MRPHLNO-041208-1	Zfish	PMID:17437127
Biological Process	GO:0001942	hair follicle development	Hoxc13	IMP	MGI:MGI:1926422	Mouse	PMID:9420327
Biological Process	GO:0001942	hair follicle development	Hoxc13	IMP	MGI:MGI:1926422	Mouse	PMID:21191399
Biological Process	GO:0035878	nail development	Hoxc13	IMP	MGI:MGI:1926422	Mouse	PMID:21191399
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HOXC13	IDA		Human	PMID:27506447
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HOXC13	IGI	UniProtKB:P17947	Human	PMID:27506447
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxc13	IDA		Mouse	PMID:21191399
Biological Process	GO:0043587	tongue morphogenesis	Hoxc13	IMP	MGI:MGI:1926422	Mouse	PMID:9420327

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern