Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXC4
  • Mouse genes Hoxc4
  • Rat genes
  • Zfish genes hoxc4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXC4	IDA		Human	PMID:15252056
Molecular Function	GO:0071837	HMG box domain binding	Hoxc4	IPI	UniProtKB:Q04886	Mouse	MGI:MGI:5284787|PMID:16582099
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:O43463	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q9BZ95	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P49761	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P68400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q9NQG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P23284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q16637	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q5SUL5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q86WV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q8N2W9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q8TB36	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC4	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXC4	IDA		Human	PMID:15252056
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXC4	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	HOXC4	IDA		Human	GO_REF:0000052
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc4	IMP	MGI:MGI:1857570	Mouse	PMID:8626021
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc4	IMP	MGI:MGI:2150683	Mouse	PMID:8660891
Biological Process	GO:0051216	cartilage development	Hoxc4	IMP	MGI:MGI:1857570	Mouse	PMID:8626021
Biological Process	GO:0048562	embryonic organ morphogenesis	Hoxc4	IMP	MGI:MGI:2150683	Mouse	PMID:8660891
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXC4	IDA		Human	PMID:15252056
Biological Process	GO:0001501	skeletal system development	Hoxc4	IMP	MGI:MGI:2150683	Mouse	PMID:8660891
Biological Process	GO:0001501	skeletal system development	Hoxc4	IMP	MGI:MGI:1857570	Mouse	PMID:8626021

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern