Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXD13
  • Mouse genes Hoxd13
  • Rat genes Hoxd13
  • Zfish genes hoxd13a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxd13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Hoxd13	IDA		Mouse	PMID:16672333
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Hoxd13	IDA		Mouse	PMID:27706137
Molecular Function	GO:0003677	DNA binding	HOXD13	IDA		Human	PMID:26581570
Molecular Function	GO:0003677	DNA binding	Hoxd13	IDA		Mouse	PMID:19168674
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXD13	IMP		Human	PMID:24789103
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hoxd13	IDA		Mouse	MGI:MGI:3620476|PMID:16314414
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxd13	IDA		Mouse	MGI:MGI:5795812|PMID:23995701
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxd13	IDA		Mouse	PMID:16314414
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hoxd13	IDA		Mouse	MGI:MGI:3620476|PMID:16314414
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXD13	IDA		Human	PMID:28473536
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	Hoxd13	IDA		Rat	PMID:19925654|RGD:12738235
Cellular Component	GO:0005654	nucleoplasm	HOXD13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hoxd13	IDA		Mouse	PMID:15617687
Cellular Component	GO:0005634	nucleus	Hoxd13	IDA		Rat	PMID:19925654|RGD:12738235
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:8106170
Biological Process	GO:0060602	branch elongation of an epithelium	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:9097018
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxd13	IGI	MGI:MGI:96204	Mouse	PMID:17714700
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxd13	IGI	MGI:MGI:96203	Mouse	PMID:8900279
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxd13	IGI	MGI:MGI:96203	Mouse	PMID:17714700
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxd13	IGI	MGI:MGI:95729	Mouse	PMID:17714700
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxd13	IGI	MGI:MGI:1918115	Mouse	PMID:9342042
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxd13	IGI	MGI:MGI:96204	Mouse	PMID:8900279
Biological Process	GO:0048619	embryonic hindgut morphogenesis	Hoxd13	IMP		Rat	PMID:17161201|RGD:1599527
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxd13	IMP	MGI:MGI:1857397	Mouse	PMID:11850178
Biological Process	GO:0022612	gland morphogenesis	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:9097018
Biological Process	GO:0035108	limb morphogenesis	Hoxd13	IMP	MGI:MGI:1857397	Mouse	PMID:11543619
Biological Process	GO:0035108	limb morphogenesis	Hoxd13	IGI	MGI:MGI:95462	Mouse	PMID:8978698
Biological Process	GO:0030539	male genitalia development	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:8106170
Biological Process	GO:0060571	morphogenesis of an epithelial fold	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:9097018
Biological Process	GO:0007389	pattern specification process	Hoxd13	IGI	MGI:MGI:96204	Mouse	PMID:8900279
Biological Process	GO:0007389	pattern specification process	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:8106170
Biological Process	GO:0007389	pattern specification process	Hoxd13	IMP	MGI:MGI:1857397	Mouse	PMID:11850178
Biological Process	GO:0007389	pattern specification process	Hoxd13	IGI	MGI:MGI:96203	Mouse	PMID:8900279
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXD13	IMP		Human	PMID:24789103
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxd13	IDA		Mouse	PMID:19168674
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxd13	IDA		Mouse	PMID:16314414
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxd13	IDA		Mouse	PMID:16672333
Biological Process	GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	Hoxd13	IGI	MGI:MGI:107730	Mouse	PMID:12668621
Biological Process	GO:0030850	prostate gland development	Hoxd13	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0060687	regulation of branching involved in prostate gland morphogenesis	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:9097018
Biological Process	GO:0042127	regulation of cell population proliferation	Hoxd13	IMP	MGI:MGI:1857397	Mouse	PMID:11850178
Biological Process	GO:0033574	response to testosterone	Hoxd13	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0001501	skeletal system development	Hoxd13	IMP	MGI:MGI:2151805	Mouse	PMID:8620844
Biological Process	GO:0001501	skeletal system development	Hoxd13	IMP	MGI:MGI:1857871	Mouse	PMID:8106170
Biological Process	GO:0006366	transcription by RNA polymerase II	Hoxd13	IDA		Mouse	PMID:16314414

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern