Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXD3
  • Mouse genes Hoxd3
  • Rat genes Hoxd3
  • Zfish genes hoxd3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXD3	IDA		Human	PMID:14610084
Molecular Function	GO:0005515	protein binding	HOXD3	IPI	UniProtKB:P09022	Human	PMID:23088713
Molecular Function	GO:0005515	protein binding	HOXD3	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXD3	IPI	UniProtKB:Q86VF2-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXD3	IPI	UniProtKB:Q8NI38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXD3	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXD3	IDA		Human	PMID:7913891
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXD3	IDA		Human	PMID:28473536
Cellular Component	GO:0016235	aggresome	HOXD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	HOXD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXD3	IDA		Human	GO_REF:0000052
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd3	IMP	MGI:MGI:1857959	Mouse	PMID:7913519
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd3	IGI	MGI:MGI:96175	Mouse	PMID:9441667
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd3	IGI	MGI:MGI:96175	Mouse	PMID:7913519
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd3	IMP	MGI:MGI:1857959	Mouse	PMID:7910549
Biological Process	GO:0051216	cartilage development	Hoxd3	IGI	MGI:MGI:96175	Mouse	PMID:9441667
Biological Process	GO:0051216	cartilage development	Hoxd3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0007160	cell-matrix adhesion	HOXD3	IDA		Human	PMID:7742539
Biological Process	GO:0006351	DNA-templated transcription	HOXD3	IMP		Human	PMID:12836255
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxd3	IMP	MGI:MGI:1857959	Mouse	PMID:7913519
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxd3	IGI	MGI:MGI:96175	Mouse	PMID:7913519
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxd3	IMP	MGI:MGI:1857959	Mouse	PMID:7910549
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	Hoxd3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	Hoxd3	IGI	MGI:MGI:96175	Mouse	PMID:9441667
Biological Process	GO:0007219	Notch signaling pathway	HOXD3	IMP		Human	PMID:12836255
Biological Process	GO:0010628	positive regulation of gene expression	HOXD3	IMP		Human	PMID:12836255
Biological Process	GO:0045666	positive regulation of neuron differentiation	Hoxd3	IGI	MGI:MGI:96174	Mouse	PMID:18164701
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXD3	IDA		Human	PMID:14610084
Biological Process	GO:0030878	thyroid gland development	Hoxd3	IGI	MGI:MGI:96175	Mouse	PMID:9520319

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern