Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HP,HPR
  • Mouse genes Hp
  • Rat genes Hp
  • Zfish genes hp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030492	hemoglobin binding	HP	IDA		Human	PMID:19740759
Molecular Function	GO:0030492	hemoglobin binding	Hp	IDA		Rat	PMID:6279649|RGD:1626398
Molecular Function	GO:0042802	identical protein binding	Hp	IPI	RGD:2825	Rat	PMID:6863267|RGD:1626396
Molecular Function	GO:0005515	protein binding	HP	IPI	UniProtKB:P02647	Human	PMID:19758344
Molecular Function	GO:0005515	protein binding	HP	IPI	UniProtKB:P02649	Human	PMID:19758344
Molecular Function	GO:0005515	protein binding	HP	IPI	UniProtKB:Q9Y282	Human	PMID:31142615
Cellular Component	GO:0072562	blood microparticle	HP	HDA		Human	PMID:22516433
Cellular Component	GO:0072562	blood microparticle	HPR	HDA		Human	PMID:22516433
Cellular Component	GO:0072562	blood microparticle	Hp	IDA		Rat	PMID:22014850|RGD:5688769
Cellular Component	GO:0005783	endoplasmic reticulum	Hp	IDA		Rat	PMID:6863267|RGD:1626396
Cellular Component	GO:0070062	extracellular exosome	HP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	HP	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	HPR	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	HP	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	HP	IDA		Human	PMID:19433579
Cellular Component	GO:0005615	extracellular space	HP	IDA		Human	PMID:21805676
Cellular Component	GO:0005615	extracellular space	HP	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	HP	IDA		Human	PMID:25645918
Cellular Component	GO:0005615	extracellular space	Hp	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Hp	IDA		Rat	PMID:17161237|RGD:1626339
Cellular Component	GO:0005794	Golgi apparatus	Hp	IDA		Rat	PMID:6863267|RGD:1626396
Cellular Component	GO:0031838	haptoglobin-hemoglobin complex	HP	IDA		Human	PMID:19740759
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	HPR	IDA		Human	PMID:16682745
Biological Process	GO:0002526	acute inflammatory response	Hp	IEP		Rat	PMID:12669191|RGD:1626376
Biological Process	GO:0007568	aging	Hp	IEP		Rat	PMID:25140128|RGD:11041801
Biological Process	GO:0031100	animal organ regeneration	Hp	IEP		Rat	PMID:12379430|RGD:1626377
Biological Process	GO:0001889	liver development	Hp	IDA		Rat	PMID:16172914|RGD:1625368
Biological Process	GO:2000296	negative regulation of hydrogen peroxide catabolic process	HP	IDA		Human	PMID:19740759
Biological Process	GO:0051354	negative regulation of oxidoreductase activity	HP	IDA		Human	PMID:19740759
Biological Process	GO:0007219	Notch signaling pathway	Hp	IDA		Mouse	PMID:23117660
Biological Process	GO:0010942	positive regulation of cell death	HP	IDA		Human	PMID:19740759
Biological Process	GO:0009617	response to bacterium	Hp	IEP		Mouse	PMID:23012479
Biological Process	GO:0033590	response to cobalamin	Hp	IEP		Rat	PMID:12769818|RGD:1643101
Biological Process	GO:0051602	response to electrical stimulus	Hp	IEP		Rat	PMID:9435654|RGD:1626394
Biological Process	GO:0051384	response to glucocorticoid	Hp	IEP		Rat	PMID:9749840|RGD:1626392
Biological Process	GO:0060416	response to growth hormone	Hp	IEP		Rat	PMID:16127721|RGD:1626369
Biological Process	GO:0009408	response to heat	Hp	IEP		Rat	PMID:10783913|RGD:1626383
Biological Process	GO:0042542	response to hydrogen peroxide	HP	IDA		Human	PMID:19740759
Biological Process	GO:0001666	response to hypoxia	Hp	IEP		Rat	PMID:3094379|RGD:1626356
Biological Process	GO:0033591	response to L-ascorbic acid	Hp	IEP		Rat	PMID:9566989|RGD:1643102
Biological Process	GO:0010288	response to lead ion	Hp	IEP		Rat	PMID:9082656|RGD:1626395
Biological Process	GO:0032496	response to lipopolysaccharide	Hp	IEP		Rat	PMID:16968543|RGD:1626367
Biological Process	GO:0032026	response to magnesium ion	Hp	IEP		Rat	PMID:11300617|RGD:1626379
Biological Process	GO:0014070	response to organic cyclic compound	Hp	IEP		Rat	PMID:15856910|RGD:1626372
Biological Process	GO:0010033	response to organic substance	Hp	IEP		Rat	PMID:14757319|RGD:1626373
Biological Process	GO:0042594	response to starvation	Hp	IEP		Rat	PMID:19053136|RGD:11041864
Biological Process	GO:0010165	response to X-ray	Hp	IEP		Rat	PMID:12379430|RGD:1626377
Biological Process	GO:0009410	response to xenobiotic stimulus	Hp	IEP		Rat	PMID:15899029|RGD:1626370
Biological Process	GO:0007283	spermatogenesis	Hp	IEP		Rat	PMID:9432136|RGD:1626393

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern