Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hpca

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HPCA
- Mouse genes Hpca
- Rat genes Hpca
- Zfish genes hpca
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hpca

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	HPCA	IDA		Human	PMID:11964161
Molecular Function	GO:0005509	calcium ion binding	HPCA	IDA		Human	PMID:28398555
Molecular Function	GO:0005509	calcium ion binding	Hpca	IDA		Rat	PMID:1543495\|RGD:9686440
Molecular Function	GO:0005509	calcium ion binding	Hpca	IDA		Rat	PMID:8360179\|RGD:12907550
Molecular Function	GO:0042802	identical protein binding	HPCA	IDA		Human	PMID:28398555
Molecular Function	GO:0019900	kinase binding	Hpca	IPI	RGD:2357	Rat	PMID:23142228\|RGD:9686444
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:O15427	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:P0CG20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:P12532	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:P14927	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:P55197-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q03060-25	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q2TAL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q969H8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q9BWX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q9BXJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPCA	IPI	UniProtKB:Q9UBH0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Hpca	IPI	UniProtKB:Q08460	Mouse	MGI:MGI:3852248\|PMID:19423573
Molecular Function	GO:0005515	protein binding	Hpca	IPI	PR:Q3TDX8	Mouse	PMID:14739275
Molecular Function	GO:0005515	protein binding	Hpca	IPI	UniProtKB:P14100	Rat	PMID:16470652\|RGD:8554798
Cellular Component	GO:0030424	axon	Hpca	IDA		Rat	PMID:7789406\|RGD:9686441
Cellular Component	GO:0005737	cytoplasm	HPCA	IDA		Human	PMID:28398555
Cellular Component	GO:0005829	cytosol	Hpca	IDA		Rat	PMID:1543495\|RGD:9686440
Cellular Component	GO:0032839	dendrite cytoplasm	Hpca	IDA		Rat	PMID:8233019\|RGD:9686436
Cellular Component	GO:0032590	dendrite membrane	Hpca	IDA		Rat	PMID:8233019\|RGD:9686436
Cellular Component	GO:0044327	dendritic spine head	Hpca	IDA		Rat	PMID:20704590\|RGD:9686447
Cellular Component	GO:0019898	extrinsic component of membrane	Hpca	IDA		Rat	PMID:1543495\|RGD:9686440
Cellular Component	GO:0019898	extrinsic component of membrane	Hpca	IDA		Rat	PMID:8360179\|RGD:12907550
Cellular Component	GO:0098978	glutamatergic synapse	Hpca	IDA		Rat	PMID:20704590\|RGD:9686447
Cellular Component	GO:0098978	glutamatergic synapse	Hpca	IMP		Rat	PMID:20704590\|RGD:9686447
Cellular Component	GO:0098978	glutamatergic synapse	Hpca	IDA		Rat	PMID:20852624\|RGD:13702412
Cellular Component	GO:0098978	glutamatergic synapse	Hpca	IMP		Rat	PMID:20852624\|RGD:13702412
Cellular Component	GO:0032809	neuronal cell body membrane	Hpca	IDA		Rat	PMID:8233019\|RGD:9686436
Cellular Component	GO:0043204	perikaryon	Hpca	IDA		Rat	PMID:8233019\|RGD:9686436
Cellular Component	GO:0098794	postsynapse	Hpca	IDA		Rat	PMID:20704590\|RGD:9686447
Cellular Component	GO:0098794	postsynapse	Hpca	IMP		Rat	PMID:20704590\|RGD:9686447
Biological Process	GO:0031584	activation of phospholipase D activity	Hpca	IDA		Rat	PMID:11211872\|RGD:9686445
Biological Process	GO:0007420	brain development	Hpca	IEP		Rat	PMID:7955346\|RGD:9686439
Biological Process	GO:0019722	calcium-mediated signaling	Hpca	IEP		Rat	PMID:20704590\|RGD:9686447
Biological Process	GO:0071277	cellular response to calcium ion	HPCA	IMP		Human	PMID:28398555
Biological Process	GO:0071257	cellular response to electrical stimulus	Hpca	IEP		Rat	PMID:20704590\|RGD:9686447
Biological Process	GO:1905232	cellular response to L-glutamate	Hpca	IDA		Rat	PMID:20704590\|RGD:9686447
Biological Process	GO:0048839	inner ear development	Hpca	IDA		Mouse	PMID:21795542
Biological Process	GO:0031283	negative regulation of guanylate cyclase activity	Hpca	IDA		Rat	PMID:15336960\|RGD:9686438
Biological Process	GO:0045762	positive regulation of adenylate cyclase activity	Hpca	IDA		Rat	PMID:15336960\|RGD:9686438
Biological Process	GO:0010518	positive regulation of phospholipase activity	Hpca	IDA		Rat	PMID:11211872\|RGD:9686445
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Hpca	IDA		Rat	PMID:23142228\|RGD:9686444
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hpca	IDA		Rat	PMID:20852624\|RGD:13702412
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hpca	IMP		Rat	PMID:20852624\|RGD:13702412
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	HPCA	IMP		Human	PMID:28398555
Biological Process	GO:1904010	response to Aroclor 1254	Hpca	IEP		Rat	PMID:18602130\|RGD:2303788
Biological Process	GO:1901986	response to ketamine	Hpca	IEP		Rat	PMID:12614903\|RGD:9686446
Biological Process	GO:1902065	response to L-glutamate	Hpca	IEP		Rat	PMID:20704590\|RGD:9686447
Biological Process	GO:0014070	response to organic cyclic compound	Hpca	IEP		Rat	PMID:18602130\|RGD:2303788
Biological Process	GO:0060041	retina development in camera-type eye	Hpca	IEP		Rat	PMID:7789406\|RGD:9686441

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.