Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HPD
  • Mouse genes Hpd
  • Rat genes Hpd
  • Zfish genes hpda,hpdb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hpd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	HPD	IDA		Human	PMID:1339442
Molecular Function	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	HPD	IDA		Human	PMID:31537781
Molecular Function	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	Hpd	IDA		Rat	PMID:12867153|RGD:632936
Molecular Function	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	Hpd	IDA		Rat	PMID:15301540|RGD:151356621
Molecular Function	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	Hpd	IDA		Rat	PMID:8814303|RGD:8554707
Molecular Function	GO:0005506	iron ion binding	Hpd	IDA		Rat	PMID:15301540|RGD:151356621
Molecular Function	GO:0005515	protein binding	Hpd	IPI	PR:Q924X7	Mouse	PMID:31537781
Molecular Function	GO:0005515	protein binding	Hpd	IPI	PR:Q8VBW8	Mouse	PMID:31537781
Molecular Function	GO:0042803	protein homodimerization activity	HPD	IDA		Human	PMID:1339442
Molecular Function	GO:0042803	protein homodimerization activity	Hpd	IDA		Rat	PMID:15301540|RGD:151356621
Cellular Component	GO:0005783	endoplasmic reticulum	Hpd	IDA		Rat	PMID:12867153|RGD:632936
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Hpd	IDA		Rat	PMID:12867153|RGD:632936
Cellular Component	GO:0070062	extracellular exosome	HPD	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	Hpd	IDA		Rat	PMID:12867153|RGD:632936
Cellular Component	GO:0000139	Golgi membrane	Hpd	IDA		Rat	PMID:12867153|RGD:632936
Biological Process	GO:0006572	tyrosine catabolic process	HPD	IDA		Human	PMID:31537781
Biological Process	GO:0006572	tyrosine catabolic process	Hpd	IDA		Rat	PMID:8814303|RGD:8554707

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern