Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HPGDS
  • Mouse genes Hpgds
  • Rat genes Hpgds
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hpgds

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	HPGDS	IDA		Human	PMID:12627223
Molecular Function	GO:0000287	magnesium ion binding	HPGDS	IDA		Human	PMID:12627223
Molecular Function	GO:0004667	prostaglandin-D synthase activity	HPGDS	IDA		Human	PMID:12627223
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Hpgds	IDA		Mouse	PMID:10824118
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:P08582-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:Q96B67	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:Q96GS6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:Q96GS6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:P15018	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:Q13370	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:Q8N1H7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HPGDS	IPI	UniProtKB:Q96B67	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	HPGDS	IPI	UniProtKB:O60760	Human	PMID:12627223
Cellular Component	GO:0005829	cytosol	HPGDS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	HPGDS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HPGDS	IDA		Human	GO_REF:0000052
Biological Process	GO:2000255	negative regulation of male germ cell proliferation	Hpgds	IGI	MGI:MGI:99261	Mouse	PMID:25142465
Biological Process	GO:0006693	prostaglandin metabolic process	HPGDS	IDA		Human	PMID:12627223
Biological Process	GO:0006693	prostaglandin metabolic process	Hpgds	IDA		Mouse	PMID:10824118

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern