Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HPS6
  • Mouse genes Hps6
  • Rat genes Hps6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hps6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	HPS6	IPI	UniProtKB:P57729	Human	PMID:22511774
Molecular Function	GO:0030742	GTP-dependent protein binding	HPS6	IPI	UniProtKB:Q13637	Human	PMID:22511774
Molecular Function	GO:0005515	protein binding	HPS6	IPI	UniProtKB:Q14203	Human	PMID:25189619
Molecular Function	GO:0005515	protein binding	HPS6	IPI	UniProtKB:Q969F9	Human	PMID:25189619
Molecular Function	GO:0005515	protein binding	HPS6	IPI	UniProtKB:Q9UPZ3	Human	PMID:25189619
Molecular Function	GO:0005515	protein binding	Hps6	IPI	UniProtKB:O08788	Mouse	MGI:MGI:5805360|PMID:25189619
Molecular Function	GO:0005515	protein binding	Hps6	IPI	PR:P59438	Mouse	PMID:12548288
Molecular Function	GO:0031267	small GTPase binding	HPS6	IPI	UniProtKB:P57729	Human	PMID:22511774
Molecular Function	GO:0031267	small GTPase binding	HPS6	IPI	UniProtKB:Q13637	Human	PMID:22511774
Cellular Component	GO:0031084	BLOC-2 complex	HPS6	IPI		Human	PMID:15030569
Cellular Component	GO:0031084	BLOC-2 complex	HPS6	IPI	UniProtKB:Q969F9	Human	PMID:15030569
Cellular Component	GO:0031084	BLOC-2 complex	HPS6	IPI	UniProtKB:Q9UPZ3	Human	PMID:15030569
Cellular Component	GO:0005765	lysosomal membrane	HPS6	IDA		Human	PMID:25189619
Cellular Component	GO:0016020	membrane	HPS6	HDA		Human	PMID:19946888
Biological Process	GO:0007596	blood coagulation	Hps6	IMP	MGI:MGI:1856544	Mouse	PMID:6696991
Biological Process	GO:0032418	lysosome localization	HPS6	IMP		Human	PMID:25189619
Biological Process	GO:0032418	lysosome localization	Hps6	IMP		Mouse	MGI:MGI:5805360|PMID:25189619
Biological Process	GO:0006996	organelle organization	Hps6	IMP	MGI:MGI:1856544	Mouse	PMID:12548288
Biological Process	GO:0043473	pigmentation	Hps6	IMP	MGI:MGI:1856544	Mouse	PMID:15265785
Biological Process	GO:0043473	pigmentation	Hps6	IMP	MGI:MGI:1856544	Mouse	PMID:2379821
Biological Process	GO:0043473	pigmentation	Hps6	IMP	MGI:MGI:1856544	Mouse	PMID:17247639
Biological Process	GO:0043473	pigmentation	Hps6	IMP	MGI:MGI:1856147	Mouse	PMID:2379821
Biological Process	GO:0072657	protein localization to membrane	HPS6	IMP		Human	PMID:22511774

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern