Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HRH1
  • Mouse genes Hrh1
  • Rat genes Hrh1
  • Zfish genes hrh1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hrh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051381	histamine binding	Hrh1	IMP		Rat	PMID:7678492|RGD:728732
Molecular Function	GO:0004969	histamine receptor activity	hrh1	IDA		Zfish	PMID:17266939
Cellular Component	GO:0005829	cytosol	HRH1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	HRH1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007268	chemical synaptic transmission	Hrh1	IDA		Rat	PMID:12419527|RGD:727463
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	hrh1	IDA		Zfish	PMID:17266939|ZFIN:ZDB-PUB-070212-13
Biological Process	GO:0007613	memory	Hrh1	IMP	MGI:MGI:2182945	Mouse	PMID:17145090
Biological Process	GO:0010894	negative regulation of steroid biosynthetic process	Hrh1	IMP		Rat	PMID:15917347|RGD:2316921
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Hrh1	IDA		Rat	PMID:12419527|RGD:727463
Biological Process	GO:0045907	positive regulation of vasoconstriction	Hrh1	IMP		Rat	PMID:17169617|RGD:1642309
Biological Process	GO:0048167	regulation of synaptic plasticity	Hrh1	IMP	MGI:MGI:2182945	Mouse	PMID:17145090
Biological Process	GO:0009629	response to gravity	Hrh1	IEP		Rat	PMID:18607976|RGD:2316917
Biological Process	GO:0008542	visual learning	Hrh1	IMP	MGI:MGI:2182945	Mouse	PMID:17145090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern