Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HRH2
  • Mouse genes Hrh2
  • Rat genes Hrh2
  • Zfish genes hrh2a,hrh2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hrh2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1901363	heterocyclic compound binding	Hrh2	IDA		Rat	PMID:1313563|RGD:9685527
Molecular Function	GO:0004969	histamine receptor activity	Hrh2	IDA		Rat	PMID:1313563|RGD:9685527
Molecular Function	GO:0004969	histamine receptor activity	hrh2a	IDA		Zfish	PMID:17266939
Cellular Component	GO:0016020	membrane	Hrh2	IDA		Rat	PMID:1313563|RGD:9685527
Biological Process	GO:0071420	cellular response to histamine	Hrh2	IEP		Rat	PMID:1313563|RGD:9685527
Biological Process	GO:0048565	digestive tract development	Hrh2	IMP	MGI:MGI:3607154	Mouse	PMID:15476751
Biological Process	GO:0048565	digestive tract development	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:10862789
Biological Process	GO:0003382	epithelial cell morphogenesis	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:10862789
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	hrh2a	IDA		Zfish	PMID:17266939|ZFIN:ZDB-PUB-070212-13
Biological Process	GO:0001696	gastric acid secretion	Hrh2	IGI	MGI:MGI:99479	Mouse	PMID:15476751
Biological Process	GO:0001698	gastrin-induced gastric acid secretion	Hrh2	IMP	MGI:MGI:3607154	Mouse	PMID:15476751
Biological Process	GO:0001698	gastrin-induced gastric acid secretion	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:10862789
Biological Process	GO:0048732	gland development	Hrh2	IMP	MGI:MGI:3607154	Mouse	PMID:15476751
Biological Process	GO:0001697	histamine-induced gastric acid secretion	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:10862789
Biological Process	GO:0001697	histamine-induced gastric acid secretion	Hrh2	IMP	MGI:MGI:3607154	Mouse	PMID:15476751
Biological Process	GO:0007613	memory	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:17145090
Biological Process	GO:1900139	negative regulation of arachidonic acid secretion	Hrh2	IDA		Rat	PMID:1313563|RGD:9685527
Biological Process	GO:0048167	regulation of synaptic plasticity	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:17145090
Biological Process	GO:1901998	toxin transport	Hrh2	IMP		Mouse	PMID:23716698
Biological Process	GO:0008542	visual learning	Hrh2	IMP	MGI:MGI:2182949	Mouse	PMID:17145090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern