Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HRH3
  • Mouse genes Hrh3
  • Rat genes Hrh3
  • Zfish genes hrh3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hrh3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043176	amine binding	Hrh3	IPI	CHEBI:81391	Rat	PMID:10869375|RGD:632981
Molecular Function	GO:1901363	heterocyclic compound binding	Hrh3	IPI	CHEBI:81390|CHEBI:64177|CHEBI:64156|CHEBI:73337|CHEBI:29009	Rat	PMID:10869375|RGD:632981
Molecular Function	GO:0004969	histamine receptor activity	hrh3	IDA		Zfish	PMID:17266939
Molecular Function	GO:0097159	organic cyclic compound binding	Hrh3	IMP		Rat	PMID:11090094|RGD:152985533
Cellular Component	GO:0043209	myelin sheath	Hrh3	IDA		Rat	PMID:1647769|RGD:1626435
Cellular Component	GO:0043005	neuron projection	Hrh3	IDA		Rat	PMID:17027043|RGD:1626422
Cellular Component	GO:0005886	plasma membrane	Hrh3	IDA		Rat	PMID:1647769|RGD:1626435
Biological Process	GO:0007420	brain development	Hrh3	IEP		Rat	PMID:14664812|RGD:1626434
Biological Process	GO:0046058	cAMP metabolic process	Hrh3	IDA		Rat	PMID:11130725|RGD:151708734
Biological Process	GO:0050890	cognition	Hrh3	IMP		Rat	PMID:17327487|RGD:1626419
Biological Process	GO:0042756	drinking behavior	Hrh3	IMP		Rat	PMID:17327487|RGD:1626419
Biological Process	GO:0042755	eating behavior	Hrh3	IMP		Rat	PMID:17189541|RGD:1626405
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	hrh3	IDA		Zfish	PMID:17266939|ZFIN:ZDB-PUB-070212-13
Biological Process	GO:0007612	learning	Hrh3	IMP		Rat	PMID:17327487|RGD:1626419
Biological Process	GO:0007613	memory	Hrh3	IMP		Rat	PMID:15695163|RGD:1626427
Biological Process	GO:0007194	negative regulation of adenylate cyclase activity	Hrh3	IDA		Rat	PMID:10869375|RGD:632981
Biological Process	GO:0045776	negative regulation of blood pressure	Hrh3	IMP		Rat	PMID:9050021|RGD:1626409
Biological Process	GO:0014053	negative regulation of gamma-aminobutyric acid secretion	Hrh3	IMP		Rat	PMID:17350613|RGD:1626417
Biological Process	GO:0014050	negative regulation of glutamate secretion	Hrh3	IMP		Rat	PMID:17027043|RGD:1626422
Biological Process	GO:0014063	negative regulation of serotonin secretion	Hrh3	IMP		Rat	PMID:15470136|RGD:1626430
Biological Process	GO:0090238	positive regulation of arachidonic acid secretion	Hrh3	IDA		Rat	PMID:11130725|RGD:151708734
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Hrh3	IMP		Rat	PMID:17350613|RGD:1626417
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Hrh3	IMP		Rat	PMID:16682020|RGD:1626424
Biological Process	GO:0014061	regulation of norepinephrine secretion	Hrh3	IMP		Rat	PMID:15076218|RGD:1626433
Biological Process	GO:1904321	response to forskolin	Hrh3	IDA		Rat	PMID:11130725|RGD:151708734
Biological Process	GO:0014070	response to organic cyclic compound	Hrh3	IMP		Rat	PMID:16316645|RGD:1626406

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern