Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HRK
  • Mouse genes Hrk
  • Rat genes Hrk
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hrk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HRK	IPI	UniProtKB:Q07817-1	Human	PMID:14596824
Molecular Function	GO:0005515	protein binding	HRK	IPI	UniProtKB:Q07021	Human	PMID:15031724
Molecular Function	GO:0005515	protein binding	HRK	IPI	UniProtKB:Q07817-1	Human	PMID:15031724
Molecular Function	GO:0005515	protein binding	HRK	IPI	UniProtKB:Q07817-1	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	Hrk	IPI	RGD:2200	Rat	PMID:10075695|RGD:70327
Cellular Component	GO:0005739	mitochondrion	HRK	IDA		Human	PMID:15031724
Biological Process	GO:0006915	apoptotic process	Hrk	IMP		Rat	PMID:10075695|RGD:70327
Biological Process	GO:0051365	cellular response to potassium ion starvation	Hrk	IMP		Rat	PMID:17428807|RGD:2290488
Biological Process	GO:0043065	positive regulation of apoptotic process	HRK	IMP		Human	PMID:15031724
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Hrk	IMP		Rat	PMID:17428807|RGD:2290488
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	HRK	IDA		Human	PMID:21041309
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	HRK	IDA		Human	PMID:21041309

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern