Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HS6ST1
  • Mouse genes Hs6st1
  • Rat genes Hs6st1
  • Zfish genes hs6st1a,hs6st1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hs6st1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017095	heparan sulfate 6-O-sulfotransferase activity	Hs6st1	IDA		Mouse	PMID:15226404
Molecular Function	GO:0017095	heparan sulfate 6-O-sulfotransferase activity	Hs6st1	IDA		Mouse	PMID:12611590
Molecular Function	GO:0017095	heparan sulfate 6-O-sulfotransferase activity	Hs6st1	IDA		Mouse	PMID:10644753
Molecular Function	GO:0017095	heparan sulfate 6-O-sulfotransferase activity	hs6st1a	IMP	ZFIN:ZDB-MRPHLNO-050906-8	Zfish	PMID:16009360
Molecular Function	GO:0017095	heparan sulfate 6-O-sulfotransferase activity	hs6st1a	IMP	ZFIN:ZDB-MRPHLNO-050906-7	Zfish	PMID:16009360
Molecular Function	GO:0005515	protein binding	HS6ST1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HS6ST1	IPI	UniProtKB:Q15323	Human	PMID:32296183
Cellular Component	GO:0005794	Golgi apparatus	Hs6st1	IDA		Mouse	PMID:24326668
Cellular Component	GO:0005794	Golgi apparatus	Hs6st1	IDA		Mouse	PMID:15226404
Biological Process	GO:0001525	angiogenesis	Hs6st1	IMP	MGI:MGI:3715259	Mouse	PMID:17405882
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Hs6st1	IDA		Mouse	PMID:12611590
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Hs6st1	IDA		Mouse	PMID:15226404
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Hs6st1	IMP		Mouse	PMID:30377379
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Hs6st1	IMP	MGI:MGI:3715259	Mouse	PMID:17405882
Biological Process	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	Hs6st1	IDA		Mouse	PMID:10644753
Biological Process	GO:0060716	labyrinthine layer blood vessel development	Hs6st1	IMP	MGI:MGI:3715259	Mouse	PMID:17405882
Biological Process	GO:0048286	lung alveolus development	Hs6st1	IMP	MGI:MGI:3715259	Mouse	PMID:17405882
Biological Process	GO:0048666	neuron development	HS6ST1	IMP		Human	PMID:21700882

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern