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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hsd3b3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd3b3
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHSD3B2IDAHumanPMID:1944309
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHSD3B2IMPHumanPMID:25322271
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHsd3b2IDARatPMID:1985917|RGD:632871
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityhsd3b2IDAZfishPMID:25974401
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityhsd3b1IDAZfishPMID:25974401
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q13520HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q7RTY0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q9NUH8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P06396HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P22607HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P27797HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P36957HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q8TDX7HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B2IPIUniProtKB:Q53GS7HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B2IPIUniProtKB:Q7Z699HumanPMID:32814053
Molecular FunctionGO:0004769steroid delta-isomerase activityHSD3B2IDAHumanPMID:1944309
Molecular FunctionGO:0004769steroid delta-isomerase activityHSD3B2IMPHumanPMID:25322271
Molecular FunctionGO:0004769steroid delta-isomerase activityHsd3b2IDARatPMID:1985917|RGD:632871
Cellular ComponentGO:0005783endoplasmic reticulumHSD3B1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005783endoplasmic reticulumHSD3B2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005783endoplasmic reticulumHSD3B2IMPHumanPMID:25322271
Cellular ComponentGO:0045171intercellular bridgeHSD3B1IDAHumanGO_REF:0000052
Cellular ComponentGO:0045171intercellular bridgeHSD3B2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005743mitochondrial inner membraneHSD3B1IDAHumanPMID:8274411
Cellular ComponentGO:0005743mitochondrial inner membraneHsd3b3HDAMousePMID:12865426
Cellular ComponentGO:0005758mitochondrial intermembrane spaceHSD3B1IDAHumanPMID:8274411
Cellular ComponentGO:0005730nucleolusHSD3B1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005730nucleolusHSD3B2IDAHumanGO_REF:0000052
Biological ProcessGO:0006702androgen biosynthetic processHSD3B2IMPHumanPMID:25322271
Biological ProcessGO:0006702androgen biosynthetic processHsd3b2IDARatPMID:1985917|RGD:632871
Biological ProcessGO:0006700C21-steroid hormone biosynthetic processHsd3b2IDARatPMID:1985917|RGD:632871
Biological ProcessGO:0048598embryonic morphogenesishsd3b2IMPZFIN:ZDB-MRPHLNO-060301-5ZfishPMID:25974401
Biological ProcessGO:0021766hippocampus developmentHsd3b2IEPRatPMID:21047951|RGD:4145527
Biological ProcessGO:0033327Leydig cell differentiationHsd3b2IEPRatPMID:18502897|RGD:4781870
Biological ProcessGO:0034757negative regulation of iron ion transportHsd3b2IMPRatPMID:16116051|RGD:1599701
Biological ProcessGO:0043473pigmentationhsd3b1IMPZFIN:ZDB-MRPHLNO-151022-4ZfishPMID:25974401
Biological ProcessGO:0046686response to cadmium ionHsd3b2IEPRatPMID:18972398|RGD:4890965
Biological ProcessGO:0051412response to corticosteroneHsd3b2IEPRatPMID:8027581|RGD:4889559
Biological ProcessGO:0034698response to gonadotropinHsd3b2IEPRatPMID:16139340|RGD:4145663
Biological ProcessGO:0010288response to lead ionHsd3b2IEPRatPMID:18972398|RGD:4890965
Biological ProcessGO:0006694steroid biosynthetic processHSD3B2IDAHumanPMID:1944309
Biological ProcessGO:0006694steroid biosynthetic processHSD3B2IMPHumanPMID:25322271
Biological ProcessGO:0006694steroid biosynthetic processhsd3b2IMPZFIN:ZDB-MRPHLNO-060301-5ZfishPMID:16437115

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory