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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hsd3b8

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd3b8
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHSD3B2IDAHumanPMID:1944309
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHSD3B2IMPHumanPMID:25322271
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHsd3b5IDARatPMID:16405651|RGD:1624284
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityHsd3b5IDARatPMID:4392955|RGD:2303525
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityhsd3b2IDAZfishPMID:25974401
Molecular FunctionGO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityhsd3b1IDAZfishPMID:25974401
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q13520HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q7RTY0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q9NUH8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P06396HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P22607HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P27797HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:P36957HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B1IPIUniProtKB:Q8TDX7HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B2IPIUniProtKB:Q53GS7HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingHSD3B2IPIUniProtKB:Q7Z699HumanPMID:32814053
Molecular FunctionGO:0005496steroid bindingHsd3b5IDARatPMID:16405651|RGD:1624284
Molecular FunctionGO:0004769steroid delta-isomerase activityHSD3B2IDAHumanPMID:1944309
Molecular FunctionGO:0004769steroid delta-isomerase activityHSD3B2IMPHumanPMID:25322271
Cellular ComponentGO:0005783endoplasmic reticulumHSD3B1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005783endoplasmic reticulumHSD3B2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005783endoplasmic reticulumHSD3B2IMPHumanPMID:25322271
Cellular ComponentGO:0045171intercellular bridgeHSD3B1IDAHumanGO_REF:0000052
Cellular ComponentGO:0045171intercellular bridgeHSD3B2IDAHumanGO_REF:0000052
Cellular ComponentGO:0043231intracellular membrane-bounded organelleHsd3b5IDARatPMID:8674848|RGD:1624285
Cellular ComponentGO:0005743mitochondrial inner membraneHSD3B1IDAHumanPMID:8274411
Cellular ComponentGO:0005758mitochondrial intermembrane spaceHSD3B1IDAHumanPMID:8274411
Cellular ComponentGO:0005730nucleolusHSD3B1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005730nucleolusHSD3B2IDAHumanGO_REF:0000052
Biological ProcessGO:0006702androgen biosynthetic processHSD3B2IMPHumanPMID:25322271
Biological ProcessGO:0048598embryonic morphogenesishsd3b2IMPZFIN:ZDB-MRPHLNO-060301-5ZfishPMID:25974401
Biological ProcessGO:0043473pigmentationhsd3b1IMPZFIN:ZDB-MRPHLNO-151022-4ZfishPMID:25974401
Biological ProcessGO:0042448progesterone metabolic processHsd3b5IDARatPMID:4392955|RGD:2303525
Biological ProcessGO:0050810regulation of steroid biosynthetic processHsd3b5IDARatPMID:4392955|RGD:2303525
Biological ProcessGO:0006694steroid biosynthetic processHSD3B2IDAHumanPMID:1944309
Biological ProcessGO:0006694steroid biosynthetic processHSD3B2IMPHumanPMID:25322271
Biological ProcessGO:0006694steroid biosynthetic processHsd3b5IDARatPMID:16405651|RGD:1624284
Biological ProcessGO:0006694steroid biosynthetic processhsd3b2IMPZFIN:ZDB-MRPHLNO-060301-5ZfishPMID:16437115

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory