Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSP90B1,HSP90B2P
  • Mouse genes Hsp90b1
  • Rat genes Hsp90b1
  • Zfish genes hsp90b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsp90b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	HSP90B1	IDA		Human	PMID:15082773
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:Q9NZJ5	Human	PMID:11907036
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:P03157	Human	PMID:11958450
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:P01009	Human	PMID:15845869
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:Q13438	Human	PMID:18264092
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:Q86XA0	Human	PMID:23349634
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:P04626	Human	PMID:23995768
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:P11021	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:P11021	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSP90B1	IPI	UniProtKB:Q00597	Human	PMID:9596688
Molecular Function	GO:0005515	protein binding	Hsp90b1	IPI	UniProtKB:Q9D8I1	Mouse	MGI:MGI:4866969|PMID:21093319
Molecular Function	GO:0005515	protein binding	Hsp90b1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0019903	protein phosphatase binding	HSP90B1	IDA		Human	PMID:19000834
Molecular Function	GO:0003723	RNA binding	HSP90B1	IDA		Human	PMID:11958450
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HSP90B1	HDA		Human	PMID:23658023
Cellular Component	GO:0005829	cytosol	HSP90B1	IDA		Human	PMID:9596688
Cellular Component	GO:0005783	endoplasmic reticulum	HSP90B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	HSP90B1	IDA		Human	PMID:17344063
Cellular Component	GO:0005783	endoplasmic reticulum	HSP90B1	IDA		Human	PMID:30188326
Cellular Component	GO:0005783	endoplasmic reticulum	Hsp90b1	IDA		Mouse	PMID:12135983
Cellular Component	GO:0005783	endoplasmic reticulum	Hsp90b1	IDA		Mouse	PMID:10444069
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	Hsp90b1	IDA		Mouse	MGI:MGI:5613481|PMID:12475965
Cellular Component	GO:0005788	endoplasmic reticulum lumen	HSP90B1	IDA		Human	PMID:10497210
Cellular Component	GO:0005789	endoplasmic reticulum membrane	HSP90B1	IDA		Human	PMID:10497210
Cellular Component	GO:0070062	extracellular exosome	HSP90B1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	HSP90B1	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	HSP90B1	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	HSP90B1	HDA		Human	PMID:19946888
Cellular Component	GO:0030496	midbody	HSP90B1	IDA		Human	PMID:15166316
Cellular Component	GO:0005634	nucleus	HSP90B1	HDA		Human	PMID:21630459
Cellular Component	GO:0048471	perinuclear region of cytoplasm	HSP90B1	IDA		Human	PMID:10497210
Cellular Component	GO:0032991	protein-containing complex	HSP90B1	IDA		Human	PMID:23349634
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Hsp90b1	IDA		Rat	PMID:22665516|RGD:8553430
Cellular Component	GO:0097524	sperm plasma membrane	Hsp90b1	IDA		Mouse	PMID:15252132
Biological Process	GO:0031247	actin rod assembly	HSP90B1	IDA		Human	PMID:19000834
Biological Process	GO:0071318	cellular response to ATP	HSP90B1	IDA		Human	PMID:19000834
Biological Process	GO:0071287	cellular response to manganese ion	Hsp90b1	IEP		Rat	PMID:23934647|RGD:10047151
Biological Process	GO:0050830	defense response to Gram-positive bacterium	hsp90b1	IMP	ZFIN:ZDB-MRPHLNO-171012-2	Zfish	PMID:28039206
Biological Process	GO:0043066	negative regulation of apoptotic process	HSP90B1	IMP		Human	PMID:10497210
Biological Process	GO:0043066	negative regulation of apoptotic process	HSP90B1	IMP		Human	PMID:15192333
Biological Process	GO:0035889	otolith tethering	hsp90b1	IMP		Zfish	PMID:14499652
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	HSP90B1	IDA		Human	PMID:19000834
Biological Process	GO:0001666	response to hypoxia	HSP90B1	IDA		Human	PMID:15620698
Biological Process	GO:0001666	response to hypoxia	hsp90b1	IDA		Zfish	PMID:25814654
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	HSP90B1	IMP		Human	PMID:25660456
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	HSP90B1	IMP		Human	PMID:18264092

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern