Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSPA1L
  • Mouse genes Hspa1l
  • Rat genes Hspa1l
  • Zfish genes hsp70.1,hsp70.2,hsp70.3,hsp70l,hspa1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hspa1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031072	heat shock protein binding	HSPA1L	IPI	UniProtKB:Q8WXX5	Human	PMID:17182002
Molecular Function	GO:0005515	protein binding	HSPA1L	IPI	UniProtKB:O95429	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	HSPA1L	IPI	UniProtKB:O00635	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPA1L	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HSPA1L	IPI	UniProtKB:O60260	Human	PMID:24270810
Molecular Function	GO:0051082	unfolded protein binding	HSPA1L	IDA		Human	PMID:21231916
Cellular Component	GO:0072562	blood microparticle	HSPA1L	HDA		Human	PMID:22516433
Cellular Component	GO:0044297	cell body	Hspa1l	IDA		Mouse	PMID:21880732
Cellular Component	GO:0005829	cytosol	HSPA1L	IDA		Human	PMID:21231916
Cellular Component	GO:0005759	mitochondrial matrix	Hspa1l	IDA		Rat	PMID:17376863|RGD:8554434
Cellular Component	GO:0005739	mitochondrion	Hspa1l	IDA		Rat	PMID:18385140|RGD:7241011
Cellular Component	GO:0002199	zona pellucida receptor complex	Hspa1l	IDA		Mouse	PMID:21880732
Biological Process	GO:0007339	binding of sperm to zona pellucida	Hspa1l	IDA		Mouse	PMID:21880732
Biological Process	GO:0001568	blood vessel development	hsp70l	IMP	ZFIN:ZDB-MRPHLNO-121213-3	Zfish	PMID:23139789
Biological Process	GO:0048593	camera-type eye morphogenesis	hsp70.3	IMP	ZFIN:ZDB-MRPHLNO-050726-2	Zfish	PMID:15832949
Biological Process	GO:0048593	camera-type eye morphogenesis	hsp70.1	IMP	ZFIN:ZDB-MRPHLNO-050726-1	Zfish	PMID:15832949
Biological Process	GO:0060216	definitive hemopoiesis	hsp70l	IMP	ZFIN:ZDB-MRPHLNO-121213-3	Zfish	PMID:24787902
Biological Process	GO:0060216	definitive hemopoiesis	hsp70l	IGI	ZFIN:ZDB-MRPHLNO-121213-3,ZFIN:ZDB-MRPHLNO-160211-6	Zfish	PMID:24787902
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion	HSPA1L	IMP		Human	PMID:24270810
Biological Process	GO:0042026	protein refolding	HSPA1L	IDA		Human	PMID:21231916
Biological Process	GO:0046686	response to cadmium ion	hsp70l	IDA		Zfish	PMID:17706735
Biological Process	GO:0046686	response to cadmium ion	hsp70.1	IEP		Zfish	PMID:16799861
Biological Process	GO:0009408	response to heat	hsp70l	IDA		Zfish	PMID:10751183
Biological Process	GO:0009408	response to heat	hsp70.1	IDA		Zfish	PMID:10751183
Biological Process	GO:0010038	response to metal ion	hsp70l	IDA		Zfish	PMID:26354112
Biological Process	GO:0009410	response to xenobiotic stimulus	hsp70.1	IDA		Zfish	PMID:17497411
Biological Process	GO:0009410	response to xenobiotic stimulus	hsp70.1	IDA		Zfish	PMID:18973944

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern