Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hspa8

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HSPA8
- Mouse genes Hspa8
- Rat genes Hsc70-ps1,Hspa8,LOC680121
- Zfish genes hspa8,hspa8b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hspa8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031686	A1 adenosine receptor binding	Hspa8	IPI	RGD:730818	Rat	PMID:10866672\|RGD:10059330
Molecular Function	GO:0043531	ADP binding	Hspa8	IDA		Rat	PMID:11133993\|RGD:2326097
Molecular Function	GO:0005524	ATP binding	HSPA8	IDA		Human	PMID:23921388
Molecular Function	GO:0005524	ATP binding	Hspa8	IDA		Rat	PMID:11133993\|RGD:2326097
Molecular Function	GO:0016887	ATP hydrolysis activity	Hspa8	IDA		Mouse	PMID:12588994
Molecular Function	GO:0016887	ATP hydrolysis activity	Hspa8	IDA		Rat	PMID:20060297\|RGD:10448947
Molecular Function	GO:0016887	ATP hydrolysis activity	Hspa8	IDA		Rat	PMID:9528774\|RGD:634185
Molecular Function	GO:0140545	ATP-dependent protein disaggregase activity	HSPA8	IDA		Human	PMID:23921388
Molecular Function	GO:0055131	C3HC4-type RING finger domain binding	HSPA8	IPI	UniProtKB:Q6ZRF8	Human	PMID:25281747
Molecular Function	GO:0045296	cadherin binding	HSPA8	HDA		Human	PMID:25468996
Molecular Function	GO:1990833	clathrin-uncoating ATPase activity	Hspa8	IDA		Rat	PMID:8363588\|RGD:10059376
Molecular Function	GO:0019899	enzyme binding	HSPA8	IPI	UniProtKB:Q8WXB1	Human	PMID:23921388
Molecular Function	GO:0019899	enzyme binding	Hspa8	IPI	RGD:2553	Rat	PMID:21958194\|RGD:10059326
Molecular Function	GO:0001664	G protein-coupled receptor binding	HSPA8	IPI	UniProtKB:O15354	Human	PMID:12150907
Molecular Function	GO:0031072	heat shock protein binding	HSPA8	IPI	UniProtKB:Q8WXX5	Human	PMID:17182002
Molecular Function	GO:0031072	heat shock protein binding	HSPA8	IPI	UniProtKB:P25685	Human	PMID:23921388
Molecular Function	GO:0023026	MHC class II protein complex binding	HSPA8	HDA		Human	PMID:20458337
Molecular Function	GO:0042277	peptide binding	Hspa8	IDA		Rat	PMID:8363588\|RGD:10059376
Molecular Function	GO:0001786	phosphatidylserine binding	Hspa8	IDA		Mouse	MGI:MGI:5700294\|PMID:21238931
Molecular Function	GO:1904593	prostaglandin binding	Hspa8	IPI	CHEBI:34159	Rat	PMID:21445266\|RGD:10059429
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99966	Human	PMID:10722728
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O75190	Human	PMID:10954706
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q96M98	Human	PMID:14532270
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O00170	Human	PMID:14557246
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P60709	Human	PMID:15047060
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P00533	Human	PMID:15657067
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99614	Human	PMID:15708368
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P25686-2	Human	PMID:15936278
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P05067	Human	PMID:16049941
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NZL4	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NZL4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UNE7	Human	PMID:16275660
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UNE7	Human	PMID:16293251
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q96EY1-1	Human	PMID:16531398
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P03485	Human	PMID:17022977
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q15428	Human	PMID:17332742
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q5S007	Human	PMID:17400507
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P32121	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P49407	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95801	Human	PMID:18320024
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95816	Human	PMID:18457437
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q8AZK7	Human	PMID:18457437
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P60709	Human	PMID:19338310
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99933	Human	PMID:19800331
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P05412	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q8TDR0	Human	PMID:20391533
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UNE7	Human	PMID:20618441
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NXW2	Human	PMID:21148293
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NXW2	Human	PMID:21150129
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9GZX7	Human	PMID:22085931
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95816	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NQ11	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P34932	Human	PMID:22990239
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P56696	Human	PMID:23431407
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q5S007	Human	PMID:23455607
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P00338	Human	PMID:23523103
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q969S8	Human	PMID:23801752
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UKB3	Human	PMID:24122553
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99IB8:PRO_0000045603	Human	PMID:24136289
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95816	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95817	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99933	Human	PMID:24318877
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O14976	Human	PMID:24510904
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q5S007	Human	PMID:24510904
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9H095	Human	PMID:24787902
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q5S007	Human	PMID:24947832
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O00635	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NZL4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P40692	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P08621	Human	PMID:25719862
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q53FT3	Human	PMID:25760597
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P14598	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P61764	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q96PG8	Human	PMID:26212789
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99933	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q8TEV9	Human	PMID:27103069
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q96LT7	Human	PMID:27103069
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9BPY8	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UNE7	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q8TBM8	Human	PMID:27916661
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NXW2	Human	PMID:27916661
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O14976	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q15428	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NZL4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q5S007	Human	PMID:29519959
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O14976	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95429	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95816	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P34932	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9BQI3	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9NZL4	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UNE7	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O75800	Human	PMID:29601588
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P01308:PRO_0000015820	Human	PMID:29764935
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P01893	Human	PMID:29764935
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P10636	Human	PMID:29764935
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P10636-6	Human	PMID:29764935
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95816	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P34932	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q8TDR0	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9BQI3	Human	PMID:31273097
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O00635	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q8WXX5	Human	PMID:33857403
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q9UL15	Human	PMID:35044787
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q99933	Human	PMID:9305631
Molecular Function	GO:0005515	protein binding	HSPA8	IPI	UniProtKB:Q00613	Human	PMID:9499401
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniProtKB:O41974	Mouse	MGI:MGI:5787727\|PMID:26581985
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniProtKB:Q8CI32	Mouse	MGI:MGI:7311923\|PMID:35044787
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniProtKB:P43883\|UniProtKB:Q9DBG5	Mouse	MGI:MGI:5660678\|PMID:25961502
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniProtKB:O88447	Mouse	MGI:MGI:4431152\|PMID:20111006
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:P39689	Mouse	PMID:12588994
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:Q9JLV1	Mouse	PMID:20060297
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:Q06219	Mouse	PMID:18346207
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:P25322	Mouse	PMID:12588994
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:P29752	Mouse	PMID:14644449
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	MGI:MGI:106504	Mouse	PMID:18346207
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	PR:P30285	Mouse	PMID:12588994
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	RGD:69062	Rat	PMID:10198213\|RGD:2326098
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	RGD:727936	Rat	PMID:12514190\|RGD:1299605
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniProtKB:O70593	Rat	PMID:15708368\|RGD:12050137
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	RGD:2617	Rat	PMID:17877381\|RGD:2302074
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniProtKB:P80067	Rat	PMID:18307834\|RGD:8661625
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	RGD:3694	Rat	PMID:19457116\|RGD:5130974
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	RGD:71058	Rat	PMID:23159318\|RGD:10040996
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	UniprotKB:P00711	Rat	PMID:8806721\|RGD:10059379
Molecular Function	GO:0005515	protein binding	Hspa8	IPI	RGD:621312\|RGD:621599	Rat	PMID:9528774\|RGD:634185
Molecular Function	GO:0051087	protein-folding chaperone binding	HSPA8	IPI	UniProtKB:O95816	Human	PMID:16207813
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	HSPA8	IDA		Human	PMID:11559757
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	HSPA8	IPI	UniProtKB:O95816\|UniProtKB:Q9UNE7	Human	PMID:16207813
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	HSPA8	IDA		Human	PMID:2799391
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	HSPA8	IDA		Human	PMID:36586411
Molecular Function	GO:0003723	RNA binding	HSPA8	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	HSPA8	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Hspa8	IDA		Rat	PMID:23159318\|RGD:10040996
Molecular Function	GO:0005102	signaling receptor binding	Hspa8	IPI	RGD:70488	Rat	PMID:11133993\|RGD:2326097
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HSPA8	IPI	UniProtKB:O60260	Human	PMID:12150907
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HSPA8	IPI	UniProtKB:Q9UNE7	Human	PMID:16207813
Molecular Function	GO:0051082	unfolded protein binding	HSPA8	IDA		Human	PMID:21231916
Molecular Function	GO:0051082	unfolded protein binding	Hspa8	IPI	PR:P30285	Mouse	PMID:12588994
Molecular Function	GO:0051082	unfolded protein binding	Hspa8	IPI	PR:P25322	Mouse	PMID:12588994
Molecular Function	GO:0051082	unfolded protein binding	Hspa8	IMP		Rat	PMID:11133993\|RGD:2326097
Cellular Component	GO:0032279	asymmetric synapse	Hspa8	IDA		Rat	PMID:11230095\|RGD:10059401
Cellular Component	GO:0005776	autophagosome	Hspa8	IDA		Rat	PMID:20392947\|RGD:10059398
Cellular Component	GO:0030424	axon	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0072562	blood microparticle	HSPA8	HDA		Human	PMID:22516433
Cellular Component	GO:0009986	cell surface	Hspa8	IDA		Rat	PMID:8228242\|RGD:10059407
Cellular Component	GO:0005737	cytoplasm	Hspa8	IDA		Mouse	MGI:MGI:5787727\|PMID:26581985
Cellular Component	GO:0005737	cytoplasm	Hspa8	IDA		Rat	PMID:10329212\|RGD:10059424
Cellular Component	GO:0005737	cytoplasm	Hspa8	IDA		Rat	PMID:19457116\|RGD:5130974
Cellular Component	GO:0005829	cytosol	HSPA8	IDA		Human	PMID:21231916
Cellular Component	GO:0005829	cytosol	Hspa8	IDA		Mouse	PMID:16906134
Cellular Component	GO:0005829	cytosol	Hspa8	IDA		Rat	PMID:9987077\|RGD:10059370
Cellular Component	GO:0030425	dendrite	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0043198	dendritic shaft	Hspa8	IDA		Rat	PMID:11230095\|RGD:10059401
Cellular Component	GO:0043197	dendritic spine	Hspa8	IDA		Rat	PMID:11230095\|RGD:10059401
Cellular Component	GO:0070062	extracellular exosome	HSPA8	IDA		Human	PMID:19028452
Cellular Component	GO:0070062	extracellular exosome	HSPA8	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	HSPA8	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	HSPA8	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	HSPA8	IDA		Human	PMID:21235781
Cellular Component	GO:0070062	extracellular exosome	HSPA8	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	HSPA8	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	Hspa8	IDA		Mouse	PMID:19724054
Cellular Component	GO:0070062	extracellular exosome	Hspa8	IDA		Rat	PMID:11133993\|RGD:2326097
Cellular Component	GO:0005615	extracellular space	HSPA8	HDA		Human	PMID:16502470
Cellular Component	GO:0005925	focal adhesion	HSPA8	HDA		Human	PMID:21423176
Cellular Component	GO:0098978	glutamatergic synapse	Hspa8	IDA		Mouse	PMID:28234934
Cellular Component	GO:0098978	glutamatergic synapse	Hspa8	EXP		Mouse	PMID:28234934
Cellular Component	GO:0098978	glutamatergic synapse	Hspa8	IDA		Mouse	PMID:21209184
Cellular Component	GO:0098978	glutamatergic synapse	Hspa8	IDA		Rat	PMID:11230095\|RGD:10059401
Cellular Component	GO:0098978	glutamatergic synapse	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0098690	glycinergic synapse	Hspa8	IDA		Mouse	PMID:21209184
Cellular Component	GO:0098690	glycinergic synapse	Hspa8	EXP		Rat	PMID:21209184\|RGD:13702189
Cellular Component	GO:0098690	glycinergic synapse	Hspa8	IDA		Rat	PMID:21209184\|RGD:13702189
Cellular Component	GO:0098690	glycinergic synapse	Hspa8	IMP		Rat	PMID:21209184\|RGD:13702189
Cellular Component	GO:0005882	intermediate filament	Hspa8	IDA		Rat	PMID:7721954\|RGD:10059404
Cellular Component	GO:0005622	intracellular anatomical structure	Hspa8	IDA		Mouse	PMID:9122205
Cellular Component	GO:0005770	late endosome	Hspa8	IDA		Mouse	MGI:MGI:5700294\|PMID:21238931
Cellular Component	GO:1990836	lysosomal matrix	Hspa8	IDA		Rat	PMID:18644871\|RGD:10412301
Cellular Component	GO:1990836	lysosomal matrix	Hspa8	IDA		Rat	PMID:9038169\|RGD:10059368
Cellular Component	GO:0005765	lysosomal membrane	HSPA8	IDA		Human	PMID:11559757
Cellular Component	GO:0005765	lysosomal membrane	Hspa8	IDA		Rat	PMID:18644871\|RGD:10412301
Cellular Component	GO:0005765	lysosomal membrane	Hspa8	IDA		Rat	PMID:9038169\|RGD:10059368
Cellular Component	GO:0005764	lysosome	Hspa8	IDA		Rat	PMID:23880665\|RGD:10059327
Cellular Component	GO:0016020	membrane	HSPA8	HDA		Human	PMID:19946888
Cellular Component	GO:0045121	membrane raft	Hspa8	IDA		Rat	PMID:15948182\|RGD:1624239
Cellular Component	GO:1990124	messenger ribonucleoprotein complex	Hspa8	IDA		Rat	PMID:20596529\|RGD:10043155
Cellular Component	GO:0005874	microtubule	Hspa8	IDA		Rat	PMID:2527848\|RGD:10059393
Cellular Component	GO:0043209	myelin sheath	Hspa8	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0043005	neuron projection	Hspa8	IDA		Rat	PMID:19457116\|RGD:5130974
Cellular Component	GO:0044309	neuron spine	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0043025	neuronal cell body	Hspa8	IDA		Rat	PMID:19457116\|RGD:5130974
Cellular Component	GO:0043025	neuronal cell body	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0005634	nucleus	HSPA8	IDA		Human	PMID:20176811
Cellular Component	GO:0005634	nucleus	Hspa8	IDA		Rat	PMID:10329212\|RGD:10059424
Cellular Component	GO:0005634	nucleus	Hspa8	IDA		Rat	PMID:23159318\|RGD:10040996
Cellular Component	GO:0043204	perikaryon	Hspa8	IDA		Rat	PMID:11230095\|RGD:10059401
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Hspa8	IDA		Mouse	PMID:14627652
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Hspa8	IDA		Rat	PMID:10549657\|RGD:10059381
Cellular Component	GO:0001917	photoreceptor inner segment	Hspa8	IDA		Rat	PMID:10549657\|RGD:10059381
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Hspa8	IDA		Mouse	PMID:24616664
Cellular Component	GO:0098794	postsynapse	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0099524	postsynaptic cytosol	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0014069	postsynaptic density	Hspa8	IDA		Rat	PMID:11230095\|RGD:10059401
Cellular Component	GO:0014069	postsynaptic density	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0099634	postsynaptic specialization membrane	Hspa8	IDA		Mouse	PMID:21209184
Cellular Component	GO:0098793	presynapse	Hspa8	IDA		Mouse	PMID:24616664
Cellular Component	GO:0098793	presynapse	Hspa8	IPI		Mouse	PMID:21151134
Cellular Component	GO:0098793	presynapse	Hspa8	IDA		Mouse	PMID:21151134
Cellular Component	GO:0098793	presynapse	Hspa8	IEP		Mouse	PMID:21151134
Cellular Component	GO:0098793	presynapse	Hspa8	IMP		Mouse	PMID:21151134
Cellular Component	GO:0098793	presynapse	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0099523	presynaptic cytosol	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Cellular Component	GO:0101031	protein folding chaperone complex	HSPA8	IPI	UniProtKB:O95816,UniProtKB:Q9UNE7	Human	PMID:16207813
Cellular Component	GO:0032991	protein-containing complex	Hspa8	IDA		Rat	PMID:10198213\|RGD:2326098
Cellular Component	GO:0032991	protein-containing complex	Hspa8	IDA		Rat	PMID:9528774\|RGD:634185
Cellular Component	GO:0000974	Prp19 complex	HSPA8	IPI		Human	PMID:20176811
Cellular Component	GO:0000974	Prp19 complex	HSPA8	IDA		Human	PMID:20176811
Cellular Component	GO:1990904	ribonucleoprotein complex	HSPA8	IDA		Human	PMID:17289661
Cellular Component	GO:0005681	spliceosomal complex	HSPA8	IPI		Human	PMID:20176811
Cellular Component	GO:0008021	synaptic vesicle	Hspa8	IDA		Rat	PMID:19457116\|RGD:5130974
Cellular Component	GO:0043195	terminal bouton	Hspa8	HDA		Rat	PMID:24876496\|RGD:10047219
Cellular Component	GO:0043195	terminal bouton	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325
Biological Process	GO:0007568	aging	Hspa8	IEP		Rat	PMID:10898246\|RGD:10059362
Biological Process	GO:0046034	ATP metabolic process	HSPA8	IDA		Human	PMID:23921388
Biological Process	GO:0008088	axo-dendritic transport	Hspa8	IEP		Rat	PMID:11933046\|RGD:10059372
Biological Process	GO:0071276	cellular response to cadmium ion	Hspa8	IEP		Rat	PMID:9736451\|RGD:10059378
Biological Process	GO:0034605	cellular response to heat	Hspa8	IEP		Rat	PMID:8955942\|RGD:10059375
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Hspa8	IEP		Rat	PMID:10329212\|RGD:10059424
Biological Process	GO:0021549	cerebellum development	Hspa8	IEP		Rat	PMID:9764759\|RGD:10059383
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	Hspa8	IGI	MGI:MGI:1931874	Mouse	PMID:14644449
Biological Process	GO:0061684	chaperone-mediated autophagy	Hspa8	IGI	UniProtKB:P17046-1	Rat	PMID:18644871\|RGD:10412301
Biological Process	GO:0061684	chaperone-mediated autophagy	Hspa8	IDA		Rat	PMID:18644871\|RGD:10412301
Biological Process	GO:1904764	chaperone-mediated autophagy translocation complex disassembly	Hspa8	IDA		Rat	PMID:18644871\|RGD:10412301
Biological Process	GO:0061077	chaperone-mediated protein folding	Hspa8	IDA		Mouse	PMID:21151134
Biological Process	GO:0061077	chaperone-mediated protein folding	Hspa8	IEP		Mouse	PMID:21151134
Biological Process	GO:0061077	chaperone-mediated protein folding	Hspa8	IPI		Mouse	PMID:21151134
Biological Process	GO:0061077	chaperone-mediated protein folding	Hspa8	IMP		Mouse	PMID:21151134
Biological Process	GO:0061077	chaperone-mediated protein folding	Hspa8	IDA		Rat	PMID:11133993\|RGD:2326097
Biological Process	GO:0072318	clathrin coat disassembly	Hspa8	IGI	MGI:MGI:2442153	Mouse	PMID:20160091
Biological Process	GO:0072318	clathrin coat disassembly	Hspa8	IGI	MGI:MGI:1919935	Mouse	PMID:20160091
Biological Process	GO:0072318	clathrin coat disassembly	Hspa8	IDA		Rat	PMID:8363588\|RGD:10059376
Biological Process	GO:0044849	estrous cycle	Hspa8	IEP		Rat	PMID:9990085\|RGD:10059328
Biological Process	GO:0031101	fin regeneration	hspa8	IEP		Zfish	PMID:22278371
Biological Process	GO:0030900	forebrain development	Hspa8	IEP		Rat	PMID:9878698\|RGD:10059325
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Hspa8	IEP		Rat	PMID:10198213\|RGD:2326098
Biological Process	GO:0001822	kidney development	Hspa8	IEP		Rat	PMID:9764759\|RGD:10059383
Biological Process	GO:0061738	late endosomal microautophagy	Hspa8	IMP		Mouse	MGI:MGI:5700294\|PMID:21238931
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Hspa8	EXP		Rat	PMID:21209184\|RGD:13702189
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Hspa8	IDA		Rat	PMID:21209184\|RGD:13702189
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Hspa8	IMP		Rat	PMID:21209184\|RGD:13702189
Biological Process	GO:0044788	modulation by host of viral process	Hspa8	IMP		Mouse	MGI:MGI:5787727\|PMID:26581985
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Hspa8	IMP		Rat	PMID:21958194\|RGD:10059326
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HSPA8	IDA		Human	PMID:10722728
Biological Process	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	HSPA8	IDA		Human	PMID:36586411
Biological Process	GO:1902904	negative regulation of supramolecular fiber organization	HSPA8	IDA		Human	PMID:23921388
Biological Process	GO:0044829	positive regulation by host of viral genome replication	Hspa8	IMP		Mouse	MGI:MGI:5787727\|PMID:26581985
Biological Process	GO:0043085	positive regulation of catalytic activity	Hspa8	IMP		Rat	PMID:21958194\|RGD:10059326
Biological Process	GO:0010628	positive regulation of gene expression	Hspa8	IMP		Rat	PMID:8734434\|RGD:10059392
Biological Process	GO:0097214	positive regulation of lysosomal membrane permeability	Hspa8	IMP		Rat	PMID:9038169\|RGD:10059368
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	Hspa8	IMP		Mouse	PMID:23636947
Biological Process	GO:0050766	positive regulation of phagocytosis	Hspa8	IMP		Rat	PMID:9886410\|RGD:10059405
Biological Process	GO:1904592	positive regulation of protein refolding	Hspa8	IDA		Rat	PMID:11360998\|RGD:10059391
Biological Process	GO:0045862	positive regulation of proteolysis	Hspa8	IDA		Rat	PMID:9987077\|RGD:10059370
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	hspa8	IMP	ZFIN:ZDB-MRPHLNO-070405-1,ZFIN:ZDB-MRPHLNO-140604-2	Zfish	PMID:24466061
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	Hspa8	IMP		Rat	PMID:8871636\|RGD:10059395
Biological Process	GO:0046777	protein autophosphorylation	Hspa8	IDA		Rat	PMID:8420978\|RGD:10059377
Biological Process	GO:0006457	protein folding	Hspa8	IDA		Mouse	PMID:12588994
Biological Process	GO:0006606	protein import into nucleus	Hspa8	IMP		Rat	PMID:8892974\|RGD:10059380
Biological Process	GO:1902946	protein localization to early endosome	hspa8	IMP	ZFIN:ZDB-MRPHLNO-070405-1,ZFIN:ZDB-MRPHLNO-140604-2	Zfish	PMID:24466061
Biological Process	GO:0042026	protein refolding	HSPA8	IDA		Human	PMID:21231916
Biological Process	GO:0042026	protein refolding	HSPA8	IDA		Human	PMID:25719862
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	HSPA8	IDA		Human	PMID:11559757
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	HSPA8	IMP		Human	PMID:26212789
Biological Process	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	HSPA8	IDA		Human	PMID:36586411
Biological Process	GO:0044743	protein transmembrane import into intracellular organelle	Hspa8	IEP		Rat	PMID:9038169\|RGD:10059368
Biological Process	GO:0032984	protein-containing complex disassembly	Hspa8	IMP		Rat	PMID:18644871\|RGD:10412301
Biological Process	GO:0051726	regulation of cell cycle	Hspa8	IDA		Mouse	PMID:12588994
Biological Process	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	hspa8	IMP	ZFIN:ZDB-MRPHLNO-070405-1,ZFIN:ZDB-MRPHLNO-140604-2	Zfish	PMID:24466061
Biological Process	GO:0099175	regulation of postsynapse organization	Hspa8	IDA		Mouse	PMID:28234934
Biological Process	GO:0099175	regulation of postsynapse organization	Hspa8	EXP		Mouse	PMID:28234934
Biological Process	GO:0061635	regulation of protein complex stability	Hspa8	IDA		Rat	PMID:18644871\|RGD:10412301
Biological Process	GO:0031647	regulation of protein stability	HSPA8	IMP		Human	PMID:26212789
Biological Process	GO:0014823	response to activity	Hspa8	IEP		Rat	PMID:10606824\|RGD:10059364
Biological Process	GO:0032355	response to estradiol	Hspa8	IEP		Rat	PMID:9990085\|RGD:10059328
Biological Process	GO:0045471	response to ethanol	Hspa8	IEP		Rat	PMID:12170112\|RGD:10059403
Biological Process	GO:0009408	response to heat	Hspa8	IEP		Rat	PMID:11842045\|RGD:10059374
Biological Process	GO:0010045	response to nickel cation	Hspa8	IEP		Rat	PMID:15736156\|RGD:10059324
Biological Process	GO:1990834	response to odorant	Hspa8	IEP		Rat	PMID:11268007\|RGD:10059397
Biological Process	GO:0032570	response to progesterone	Hspa8	IEP		Rat	PMID:9990085\|RGD:10059328
Biological Process	GO:0042594	response to starvation	Hspa8	IEP		Rat	PMID:9038169\|RGD:10059368
Biological Process	GO:0009410	response to xenobiotic stimulus	Hspa8	IEP		Rat	PMID:10425221\|RGD:10059382
Biological Process	GO:0007608	sensory perception of smell	Hspa8	IEP		Rat	PMID:11268007\|RGD:10059397
Biological Process	GO:0007519	skeletal muscle tissue development	Hspa8	IEP		Rat	PMID:12909603\|RGD:10059373
Biological Process	GO:1990832	slow axonal transport	Hspa8	IEP		Rat	PMID:11933046\|RGD:10059372
Biological Process	GO:0016191	synaptic vesicle uncoating	Hspa8	IDA		Rat	PMID:9878698\|RGD:10059325

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.