Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HTR3B
  • Mouse genes Htr3b
  • Rat genes Htr3b
  • Zfish genes htr3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Htr3b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0022850	serotonin-gated monoatomic cation-selective channel activity	HTR3B	IGI	UniProtKB:P46098	Human	PMID:9950429
Molecular Function	GO:0022850	serotonin-gated monoatomic cation-selective channel activity	Htr3b	IDA		Mouse	PMID:10854267
Cellular Component	GO:0030424	axon	Htr3b	IDA		Rat	PMID:17650111|RGD:2316990
Cellular Component	GO:0009986	cell surface	HTR3B	IDA		Human	PMID:16571125
Cellular Component	GO:0043025	neuronal cell body	Htr3b	IDA		Rat	PMID:17650111|RGD:2316990
Cellular Component	GO:0005886	plasma membrane	Htr3b	IDA		Mouse	PMID:10854267
Cellular Component	GO:1904602	serotonin-activated cation-selective channel complex	HTR3B	IPI		Human	PMID:16116092
Cellular Component	GO:1904602	serotonin-activated cation-selective channel complex	HTR3B	IGI	UniProtKB:P46098	Human	PMID:9950429
Biological Process	GO:0071363	cellular response to growth factor stimulus	Htr3b	IEP		Rat	PMID:10854267|RGD:61635
Biological Process	GO:0098662	inorganic cation transmembrane transport	HTR3B	IDA		Human	PMID:17392525
Biological Process	GO:0032414	positive regulation of ion transmembrane transporter activity	Htr3b	IDA		Rat	PMID:10854267|RGD:61635
Biological Process	GO:0007210	serotonin receptor signaling pathway	HTR3B	IDA		Human	PMID:17392525

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern