Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HYAL1
  • Mouse genes Hyal1
  • Rat genes Hyal1
  • Zfish genes hyal1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hyal1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0052757	chondroitin hydrolase activity	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:22451654
Molecular Function	GO:0050501	hyaluronan synthase activity	HYAL1	IDA		Human	PMID:21829529
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:11296287
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:11944887
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:17170110
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:18390475
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:19478093
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:20473947
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:20572808
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:21695196
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:21699545
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:21829529
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL1	IDA		Human	PMID:9223416
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:26887442
Cellular Component	GO:0005737	cytoplasm	HYAL1	IDA		Human	PMID:21829529
Cellular Component	GO:0031410	cytoplasmic vesicle	HYAL1	IDA		Human	PMID:18390475
Cellular Component	GO:0070062	extracellular exosome	HYAL1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	HYAL1	IDA		Human	PMID:17170110
Cellular Component	GO:0005615	extracellular space	HYAL1	IDA		Human	PMID:21695196
Cellular Component	GO:0005615	extracellular space	HYAL1	IDA		Human	PMID:9223416
Cellular Component	GO:0036117	hyaluranon cable	HYAL1	IDA		Human	PMID:16900089
Cellular Component	GO:0005764	lysosome	HYAL1	IDA		Human	PMID:16600643
Cellular Component	GO:0005764	lysosome	HYAL1	IDA		Human	PMID:20572808
Cellular Component	GO:0005764	lysosome	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:22451654
Cellular Component	GO:0005764	lysosome	Hyal1	IDA		Mouse	PMID:24667601
Biological Process	GO:0051216	cartilage development	HYAL1	IEP		Human	PMID:11944887
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	HYAL1	IDA		Human	PMID:19577615
Biological Process	GO:0071347	cellular response to interleukin-1	HYAL1	IDA		Human	PMID:18390475
Biological Process	GO:0071467	cellular response to pH	HYAL1	IDA		Human	PMID:19478093
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	HYAL1	IDA		Human	PMID:17324121
Biological Process	GO:0071356	cellular response to tumor necrosis factor	HYAL1	IEP		Human	PMID:18390475
Biological Process	GO:0071493	cellular response to UV-B	HYAL1	IDA		Human	PMID:21699545
Biological Process	GO:0030207	chondroitin sulfate catabolic process	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:22451654
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:18772348
Biological Process	GO:0030213	hyaluronan biosynthetic process	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL1	IDA		Human	PMID:11296287
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL1	IDA		Human	PMID:17170110
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL1	IDA		Human	PMID:20473947
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL1	IDA		Human	PMID:21695196
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL1	IDA		Human	PMID:21699545
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:0030214	hyaluronan catabolic process	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:22451654
Biological Process	GO:0030214	hyaluronan catabolic process	Hyal1	IMP	MGI:MGI:2658730	Mouse	PMID:26887442
Biological Process	GO:0030212	hyaluronan metabolic process	HYAL1	IDA		Human	PMID:19478093
Biological Process	GO:0006954	inflammatory response	HYAL1	IDA		Human	PMID:18390475
Biological Process	GO:0030308	negative regulation of cell growth	HYAL1	IDA		Human	PMID:18725949
Biological Process	GO:0045766	positive regulation of angiogenesis	HYAL1	IMP		Human	PMID:20473947
Biological Process	GO:0045766	positive regulation of angiogenesis	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:0045785	positive regulation of cell adhesion	HYAL1	IMP		Human	PMID:20473947
Biological Process	GO:0030307	positive regulation of cell growth	HYAL1	IMP		Human	PMID:20473947
Biological Process	GO:0010634	positive regulation of epithelial cell migration	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:0045927	positive regulation of growth	HYAL1	IDA		Human	PMID:21829529
Biological Process	GO:1900106	positive regulation of hyaluranon cable assembly	HYAL1	IDA		Human	PMID:16900089
Biological Process	GO:0046677	response to antibiotic	HYAL1	IDA		Human	PMID:11944887
Biological Process	GO:0000302	response to reactive oxygen species	HYAL1	IDA		Human	PMID:20554532
Biological Process	GO:0009615	response to virus	HYAL1	IDA		Human	PMID:11296287
Biological Process	GO:0009615	response to virus	Hyal1	IDA		Mouse	MGI:MGI:5315372|PMID:11296287

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern